CYTOCHROME P450 1A2

Investigational

Approval Year

Substance Class	Protein
Protein Type	ENZYME
Protein Sub Type	CYTOCHROME P450
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	VK4SQL11C0
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CYP1A2

Preferred Name

English

CYTOCHROME P450 1A2

Common Name

English

CYTOCHROME P450-P3

Common Name

English

CYTOCHROME P(3)450

Common Name

English

HUMAN CYTOCHROME P450 1A2

Common Name

English

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Code System

Code

Type

Description

CAS

165885-24-5

PRIMARY

UNIPROT

P05177

PRIMARY

FDA UNII

VK4SQL11C0

PRIMARY

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Subunit 0

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Details


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INHIBITOR -> METABOLIC ENZYME

Qualification:

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Amount:

[2 to 10] MICROMOLAR (average)


					34AP3BBP9T

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SUBSTRATE -> METABOLIC ENZYME

Interaction Type:

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SULFORAPHANE

INHIBITOR -> METABOLIC ENZYME

Comments:

Inhibits both CYP2E1 and CYP1A2-mediated genotoxicity therefore is relevant to human isoforms of these enzymes and may contribute to a chemopreventative activity of brocolli and related species.

Amount: