Details
Stereochemistry | ACHIRAL |
Molecular Formula | C10H8 |
Molecular Weight | 128.1705 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
C1=CC2=C(C=C1)C=CC=C2
InChI
InChIKey=UFWIBTONFRDIAS-UHFFFAOYSA-N
InChI=1S/C10H8/c1-2-6-10-8-4-3-7-9(10)5-1/h1-8H
Molecular Formula | C10H8 |
Molecular Weight | 128.1705 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
DescriptionCurator's Comment: description was created based on several sources, including:
DOI: 10.1007/978-0-387-30160-0_7643
http://npic.orst.edu/factsheets/naphgen.html
http://www.cdc.gov/niosh/npg/npgd0439.html
Curator's Comment: description was created based on several sources, including:
DOI: 10.1007/978-0-387-30160-0_7643
http://npic.orst.edu/factsheets/naphgen.html
http://www.cdc.gov/niosh/npg/npgd0439.html
Naphthalene is a crystalline aromatic hydrocarbon usually obtained by distillation of coal tar. Once used as a moth repellent, it is now important as a reactant in the production of phthalic anhydride, which in turn is used for making plasticizers, alkyd resins, and polyester resins. Other fumigant uses of naphthalene include use in soil as a fumigant pesticide, and in attic spaces to repel animals. In the past, naphthalene was administered orally to kill parasitic worms in livestock. In humans, exposure to large amounts of naphthalene may damage or destroy red blood cells. Humans, particularly children, have developed this condition after ingesting mothballs or deodorant blocks containing naphthalene. Some of the symptoms of naphthalene poisoning are fatigue, lack of appetite, restlessness, and pale skin. Exposure to large amounts of naphthalene may also cause nausea, vomiting, diarrhea, blood in the urine, and jaundice (yellow coloration of the skin).
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: map00980 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8240407 |
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Target ID: GO:0030330 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10802220 |
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Target ID: GO:0034440 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10802220 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Primary | EQUIOPATHICS WRM CLEAR Approved UseIndicated for the treatment of worm infestations |
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Palliative | ALLERGIES Approved UseUses for relief of allergy symptoms affecting the mucous membranes and skin |
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Palliative | NAPHTHALINUM Approved UseNaphtalinum helps in coryza and hay fever. |
PubMed
Title | Date | PubMed |
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Hydrocarbon deposition and soil microflora as affected by highway traffic. | 2001 |
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Characterization of the protective effects of melatonin and related indoles against alpha-naphthylisothiocyanate-induced liver injury in rats. | 2001 |
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Synthesis and pharmacology of site specific cocaine abuse treatment agents: a new synthetic methodology for methylphenidate analogs based on the Blaise reaction. | 2001 Apr |
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Occurrence and potential adverse effects of semivolatile organic compounds in streambed sediment, United States, 1992-1995. | 2001 Apr |
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A polyrotaxane series containing alpha-cyclodextrin and naphthalene-modified alpha-cyclodextrin as a light-harvesting antenna system. | 2001 Apr 1 |
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Development of new urea-functionalized silica stationary phases. Characterization and chromatographic performance. | 2001 Apr 13 |
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Complete prediction of the 1H NMR spectrum of organic molecules by DFT calculations of chemical shifts and spin-spin coupling constants. | 2001 Apr 17 |
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Solid-state structures of group 1 and group 2 metal 1,5-naphthalenedisulfonates: systematic investigation of lamellar three-dimensional networks constructed by metal arenedisulfonate. | 2001 Aug |
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Efficient polycyclic aromatic hydrocarbons dihydroxylation in direct micellar systems. | 2001 Aug 5 |
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DDT, PAH and PCB in sediments from the intertidal zone of the Bohai Sea and the Yellow Sea. | 2001 Feb |
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The effect of different oil spill remediation techniques on petroleum hydrocarbon elimination in Australian bass (Macquaria novemaculeata). | 2001 Feb |
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Preliminary characterisation of esterase and platelet-activating factor (PAF)-acetylhydrolase activities from cat flea (Ctenocephalides felis) salivary glands. | 2001 Feb |
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Metabolic capabilities of CYP2F2 with various pulmonary toxicants and its relative abundance in mouse lung subcompartments. | 2001 Feb |
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Observations on the preferential biodegradation of selected components of polyaromatic hydrocarbon mixtures. | 2001 Feb |
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Crystal structure of the 100 kDa arsenite oxidase from Alcaligenes faecalis in two crystal forms at 1.64 A and 2.03 A. | 2001 Feb 7 |
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[The toxicity variation of organic extracts in drinking water treatment processes]. | 2001 Jan |
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Absolute configuration of N-[(-)-2-(7-methoxy-1,2,3,3-tetrahydro-1-naphthyl)ethyl]cyclopropylcarboxamide, a highly potent and selective melatonin analogue. | 2001 Jan |
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The physical basis of nucleic acid base stacking in water. | 2001 Jan |
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Biochemical activities of trimetoquinol analogs at human beta(1)- and beta(3)-adrenergic receptors. | 2001 Jan |
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Application of a mechanistic desorption-biodegradation model to describe the behavior of polycyclic aromatic hydrocarbons in peat soil aggregates. | 2001 Jan |
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Structural and conformational properties of (Z)-beta-(1-naphthyl)- dehydroalanine residue. | 2001 Jan |
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Single turnover chemistry and regulation of O2 activation by the oxygenase component of naphthalene 1,2-dioxygenase. | 2001 Jan 19 |
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Structural basis for enantiomer binding and separation of a common beta-blocker: crystal structure of cellobiohydrolase Cel7A with bound (S)-propranolol at 1.9 A resolution. | 2001 Jan 5 |
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[Bacteria--degraders of polycyclic aromatic hydrocarbons, isolated from soil and bottom sediments in salt-mining areas]. | 2001 Jan-Feb |
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Synthesis and in vitro antifungal activity of 1-amino-3,4-dialkylnaphthalene-2-carbonitriles and their analogues. | 2001 Jul |
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Biodegradation of non-desorbable naphthalene in soils. | 2001 Jul 1 |
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Highly potent growth hormone secretagogues: hybrids of NN703 and ipamorelin. | 2001 Jul 23 |
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Active site characteristics of CYP4B1 probed with aromatic ligands. | 2001 Jul 24 |
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Synthesis of potential aldose reductase inhibitors based on minimal pharmacophore requirements. | 2001 Jun |
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Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion. | 2001 Jun |
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Inhaled naphthalene causes dose dependent Clara cell cytotoxicity in mice but not in rats. | 2001 Jun 1 |
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A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes. | 2001 Jun 15 |
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2-Amino-6-arylsulfonylbenzonitriles as non-nucleoside reverse transcriptase inhibitors of HIV-1. | 2001 Jun 7 |
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Characterization of volatile organic compounds in smoke at experimental fires. | 2001 Jun 8 |
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Prior exposure to aged and diluted sidestream cigarette smoke impairs bronchiolar injury and repair. | 2001 Mar |
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Influence of dispersants on the bioavailability and trophic transfer of petroleum hydrocarbons to larval topsmelt (Atherinops affinis). | 2001 Mar |
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The use of a solid adsorber resin for enrichment of bacteria with toxic substrates and to identify metabolites: degradation of naphthalene, O-, and m-xylene by sulfate-reducing bacteria. | 2001 Mar 1 |
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Laboratory spectra of cold gas phase polycyclic aromatic hydrocarbon cations, and their possible relation to the diffuse interstellar bands. | 2001 Mar 15 |
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The pi complexation of alkali and alkaline earth ions by the use of meso-octaalkylporphyrinogen and aromatic hydrocarbons. | 2001 Mar 16 |
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Solvent sublation for waste minimization in a process water stream - a pilot-scale study. | 2001 Mar 19 |
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Percutaneous absorption and skin irritation of JP-8 (jet fuel). | 2001 Mar 21 |
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Synthesis, aggregation, and binding behavior of synthetic amphiphilic receptors. | 2001 Mar 9 |
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In vitro studies of the penetration of adhesive resins into artificial caries-like lesions. | 2001 Mar-Apr |
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Mass/heat transfer in dimpled two-pass coolant passages with rotation. | 2001 May |
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Determination of photophysical rate constants for the non-protected fluid room temperature phosphorescence of several naphthalene derivatives. | 2001 May |
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Efficiency of naphthalene and salicylate degradation by a recombinant Pseudomonas putida mutant strain defective in glucose metabolism. | 2001 May |
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High-rate 3-methylcatechol production in Pseudomonas putida strains by means of a novel expression system. | 2001 May |
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Ambient air quality at the site of a former manufactured gas plant. | 2001 May |
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Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations. | 2001 May |
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Determination of trace levels of manganese in various biological and environmental samples by atomic absorption spectrometry after solid-liquid extraction and preconcentration with the ion pair formed by the nitroso-S anion and the tetradecyldimethylbenzylammonium cation. | 2001 May-Jun |
Substance Class |
Chemical
Created
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admin
on
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Fri Dec 16 21:43:42 UTC 2022
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Record UNII |
2166IN72UN
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Record Status |
Validated (UNII)
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Record Version |
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NCI_THESAURUS |
C45188
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EPA PESTICIDE CODE |
55801
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2166IN72UN
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DTXSID8020913
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2166IN72UN
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SUB128902
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C29839
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184
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M7725
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37565
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931
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1311149
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1457083
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91-20-3
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NAPHTHALENE
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202-049-5
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C031721
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naphthalene
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