Details
Stereochemistry | ACHIRAL |
Molecular Formula | C10H8 |
Molecular Weight | 128.1705 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
C1=CC2=C(C=C1)C=CC=C2
InChI
InChIKey=UFWIBTONFRDIAS-UHFFFAOYSA-N
InChI=1S/C10H8/c1-2-6-10-8-4-3-7-9(10)5-1/h1-8H
Molecular Formula | C10H8 |
Molecular Weight | 128.1705 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
DescriptionCurator's Comment: description was created based on several sources, including:
DOI: 10.1007/978-0-387-30160-0_7643
http://npic.orst.edu/factsheets/naphgen.html
http://www.cdc.gov/niosh/npg/npgd0439.html
Curator's Comment: description was created based on several sources, including:
DOI: 10.1007/978-0-387-30160-0_7643
http://npic.orst.edu/factsheets/naphgen.html
http://www.cdc.gov/niosh/npg/npgd0439.html
Naphthalene is a crystalline aromatic hydrocarbon usually obtained by distillation of coal tar. Once used as a moth repellent, it is now important as a reactant in the production of phthalic anhydride, which in turn is used for making plasticizers, alkyd resins, and polyester resins. Other fumigant uses of naphthalene include use in soil as a fumigant pesticide, and in attic spaces to repel animals. In the past, naphthalene was administered orally to kill parasitic worms in livestock. In humans, exposure to large amounts of naphthalene may damage or destroy red blood cells. Humans, particularly children, have developed this condition after ingesting mothballs or deodorant blocks containing naphthalene. Some of the symptoms of naphthalene poisoning are fatigue, lack of appetite, restlessness, and pale skin. Exposure to large amounts of naphthalene may also cause nausea, vomiting, diarrhea, blood in the urine, and jaundice (yellow coloration of the skin).
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: map00980 Sources: https://www.ncbi.nlm.nih.gov/pubmed/8240407 |
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Target ID: GO:0030330 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10802220 |
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Target ID: GO:0034440 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10802220 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Primary | EQUIOPATHICS WRM CLEAR Approved UseIndicated for the treatment of worm infestations |
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Palliative | ALLERGIES Approved UseUses for relief of allergy symptoms affecting the mucous membranes and skin |
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Palliative | NAPHTHALINUM Approved UseNaphtalinum helps in coryza and hay fever. |
PubMed
Title | Date | PubMed |
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Characterization of the protective effects of melatonin and related indoles against alpha-naphthylisothiocyanate-induced liver injury in rats. | 2001 |
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A study of light-induced proton transfer from gas phase (radical) cations to reference bases. Bracketing of proton transfer from excited ions and associated reaction kinetics. | 2001 Apr |
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Solid-state structures of group 1 and group 2 metal 1,5-naphthalenedisulfonates: systematic investigation of lamellar three-dimensional networks constructed by metal arenedisulfonate. | 2001 Aug |
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Efficient polycyclic aromatic hydrocarbons dihydroxylation in direct micellar systems. | 2001 Aug 5 |
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Uptake of polycyclic aromatic hydrocarbon compounds by the gills of the bivalve mollusk Elliptio complanata. | 2001 Feb |
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The effect of different oil spill remediation techniques on petroleum hydrocarbon elimination in Australian bass (Macquaria novemaculeata). | 2001 Feb |
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Preliminary characterisation of esterase and platelet-activating factor (PAF)-acetylhydrolase activities from cat flea (Ctenocephalides felis) salivary glands. | 2001 Feb |
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Metabolic capabilities of CYP2F2 with various pulmonary toxicants and its relative abundance in mouse lung subcompartments. | 2001 Feb |
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Synthesis, analysis and rearrangement of novel unnatural glucosinolates. | 2001 Feb 15 |
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Percutaneous permeation and skin irritation of JP-8+100 jet fuel in a porcine model. | 2001 Feb 28 |
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Steric and electronic ligand perturbations in catalysis: asymmetric allylic substitution reactions using C2-symmetrical phosphorus-chiral (bi)ferrocenyl donors. | 2001 Feb 9 |
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Absolute configuration of N-[(-)-2-(7-methoxy-1,2,3,3-tetrahydro-1-naphthyl)ethyl]cyclopropylcarboxamide, a highly potent and selective melatonin analogue. | 2001 Jan |
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The physical basis of nucleic acid base stacking in water. | 2001 Jan |
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Determination of the pesticide naptalam and its degradation products by positive and negative ion mass spectrometry. | 2001 Jan 2 |
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Oxidative coupling of O-silyl and O-alkyl enethers: application of the novel annulation sequence to the synthesis of fluorinated naphthaldehydes and naphthyl ketones. | 2001 Jan 26 |
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Synthesis and in vitro antifungal activity of 1-amino-3,4-dialkylnaphthalene-2-carbonitriles and their analogues. | 2001 Jul |
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No enhancement in bioconcentration of organic contaminants by low levels of DOM. | 2001 Jul |
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Effectiveness of an anaerobic granular activated carbon fluidized-bed bioreactor to treat soil wash fluids: a proposed strategy for remediating PCP/PAH contaminated soils. | 2001 Jul |
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Biodegradation of carbaryl by a Micrococcus species. | 2001 Jul |
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Highly potent growth hormone secretagogues: hybrids of NN703 and ipamorelin. | 2001 Jul 23 |
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Mutagenicity of electrophilic N-acyloxy-N-alkoxyamides. | 2001 Jul 25 |
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Determination of absolute configuration using vibrational circular dichroism spectroscopy: the chiral sulfoxide 1-(2-methylnaphthyl) methyl sulfoxide. | 2001 Jun 1 |
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Microcosms-experiments to assess the potential for natural attenuation of contaminated groundwater. | 2001 Mar |
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Influence of dispersants on the bioavailability and trophic transfer of petroleum hydrocarbons to larval topsmelt (Atherinops affinis). | 2001 Mar |
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Numerical simulation of the infrared emission of interstellar dust. | 2001 Mar 15 |
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A simple (14)C-respirometric method for assessing microbial catabolic potential and contaminant bioavailability. | 2001 Mar 15 |
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Pyrolysis-capillary gas chromatography-mass spectrometry for the determination of polyvinyl chloride traces in solid environmental samples. | 2001 Mar 16 |
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Percutaneous absorption and skin irritation of JP-8 (jet fuel). | 2001 Mar 21 |
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Determination of photophysical rate constants for the non-protected fluid room temperature phosphorescence of several naphthalene derivatives. | 2001 May |
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High-rate 3-methylcatechol production in Pseudomonas putida strains by means of a novel expression system. | 2001 May |
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Constitutive and inducible hydroxylase activities involved in the degradation of naphthalene by Cunninghamella elegans. | 2001 May |
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Convergent synthesis of potent peptide inhibitors of the Grb2-SH2 domain by palladium catalyzed coupling of a terminal alkyne. | 2001 May 7 |
Substance Class |
Chemical
Created
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on
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Record UNII |
2166IN72UN
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Record Status |
Validated (UNII)
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NCI_THESAURUS |
C45188
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EPA PESTICIDE CODE |
55801
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2166IN72UN
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DTXSID8020913
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2166IN72UN
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SUB128902
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C29839
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184
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m7725
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37565
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931
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1457083
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91-20-3
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NAPHTHALENE
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202-049-5
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C031721
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naphthalene
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100000174863
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