Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C10H8O |
| Molecular Weight | 144.1699 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=CC=C2C=CC=CC2=C1
InChI
InChIKey=JWAZRIHNYRIHIV-UHFFFAOYSA-N
InChI=1S/C10H8O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11H
| Molecular Formula | C10H8O |
| Molecular Weight | 144.1699 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
Overview
| CYP3A4 | CYP2C9 | CYP2D6 | hERG |
|---|---|---|---|
OverviewOther
| Other Inhibitor | Other Substrate | Other Inducer |
|---|---|---|
Drug as perpetrator​
| Target | Modality | Activity | Metabolite | Clinical evidence |
|---|---|---|---|---|
| yes [IC50 17 uM] | ||||
| yes |
Drug as victim
| Target | Modality | Activity | Metabolite | Clinical evidence |
|---|---|---|---|---|
| yes | ||||
| yes |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Urinary 1-hydroxypyrene and 2-naphthol concentrations in male Koreans. | 2001 Jan |
|
| Determining the binding capability of the mouse major urinary proteins using 2-naphthol as a fluorescent probe. | 2001 May 1 |
|
| [Treatment of 2-naphtholwastewater using air oxidation and ion exchange]. | 2001 Nov |
|
| The rational design of novel chiral oxovanadium(IV) complexes for highly enantioselective oxidative coupling of 2-naphthols. | 2002 Apr 21 |
|
| Azo-dyes photocatalytic degradation in aqueous suspension of TiO2 under solar irradiation. | 2002 Dec |
|
| Electronic determinants of photoacidity in cyanonaphthols. | 2002 Feb 13 |
|
| Synthesis and antimicrobial activity of some 1,3,4-oxadiazole derivatives. | 2002 Jul |
|
| Catalytic asymmetric oxidative couplings of 2-naphthols by tridentate N-ketopinidene-based vanadyl dicarboxylates. | 2002 Jul 25 |
|
| Correlation of urinary 1-hydroxypyrene and 2-naphthol with total suspended particulates in ambient air in municipal middle-school students in Korea. | 2002 Jul-Aug |
|
| Waste-free chemistry of diazonium salts and benign separation of coupling products in solid salt reactions. | 2002 Mar 15 |
|
| Simultaneous analysis of naphthols, phenanthrols, and 1-hydroxypyrene in urine as biomarkers of polycyclic aromatic hydrocarbon exposure: intraindividual variance in the urinary metabolite excretion profiles caused by intervention with beta-naphthoflavone induction in the rat. | 2003 Apr |
|
| Novel poly (vinyl chloride) matrix membrane electrodes for the determination of phenolic pollutants in waste water. | 2003 Apr |
|
| Highly enantioselective quinoline synthesis via ene-type cyclization of 1,7-enynes catalyzed by a cationic BINAP-palladium(II) complex. | 2003 Apr 23 |
|
| Altered expression of sulfotransferases, glucuronosyltransferases and mrp transporters in FVB/mrp1-/- mice. | 2003 Dec |
|
| Study of tropaeolin degradation by iron--proposition of a reaction mechanism. | 2003 Dec |
|
| Biodegradation during contaminant transport in porous media: 6. Impact of sorption on coupled degradation-transport behavior. | 2003 Mar |
|
| Human gastrointestinal sulfotransferases: identification and distribution. | 2003 Mar 15 |
|
| Fluorescent quenching of the 2-naphthoxide anion by aliphatic and aromatic halides. Mechanism and consequences of electron transfer reactions. | 2003 Mar 21 |
|
| Oxidative degradation of azo dyes by manganese peroxidase under optimized conditions. | 2003 Mar-Apr |
|
| Electrophilic substitution of C60F18 into phenols: HF elimination between OH and a 1,3-shifted fluorine giving benzofurano[2',3':10,26]hexadecafluro[60]fullerene and derivatives. | 2003 May 21 |
|
| Measurement of pesticides and other toxicants in amniotic fluid as a potential biomarker of prenatal exposure: a validation study. | 2003 Nov |
|
| Synthesis of alpha-amino acids via asymmetric phase transfer-catalyzed alkylation of achiral nickel(II) complexes of glycine-derived Schiff bases. | 2003 Oct 22 |
|
| Discoloration and mineralization of non-biodegradable azo dye Orange II by copper-doped TiO2 nanocatalysts. | 2004 |
|
| Effect of reverse micelles on the Rose Bengal-sensitized photo-oxidation of 1- and 2-hydroxynaphthalenes. | 2004 |
|
| Novel bentonite clay-based Fe-nanocomposite as a heterogeneous catalyst for photo-Fenton discoloration and mineralization of Orange II. | 2004 Jan 1 |
|
| 7-Hydroxynaphthalen-1-yl-urea and -amide antagonists of human vanilloid receptor 1. | 2004 Jan 19 |
|
| Simultaneous determination of 1- and 2-naphthol in human urine using on-line clean-up column-switching liquid chromatography-fluorescence detection. | 2004 Mar 5 |
|
| Influence of phenylalanines 77 and 138 on the stereospecificity of aryl sulfotransferase IV. | 2004 May |
|
| Decolorization of orange II by catalytic oxidation using iron (III) phthalocyanine-tetrasulfonic acid. | 2004 Oct 18 |
|
| Controlling the regiospecific oxidation of aromatics via active site engineering of toluene para-monooxygenase of Ralstonia pickettii PKO1. | 2005 Jan 7 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:19:24 GMT 2023
by
admin
on
Fri Dec 15 15:19:24 GMT 2023
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| Record UNII |
P2Z71CIK5H
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| Record Status |
Validated (UNII)
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| Record Version |
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| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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EPA PESTICIDE CODE |
10301
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NCI_THESAURUS |
C250
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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DTXSID5027061
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PRIMARY | |||
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135-19-3
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PRIMARY | |||
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C81517
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m7739
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PRIMARY | Merck Index | ||
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2-NAPHTHOL
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PRIMARY | |||
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100000153158
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2044
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10432
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3370
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CHEMBL14126
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P2Z71CIK5H
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C028405
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SUB127015
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6812
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205-182-7
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8663
Created by
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| Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT | |||
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SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> METABOLITE |
IN VITRO
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
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