Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C10H8O |
| Molecular Weight | 144.1699 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=CC=C2C=CC=CC2=C1
InChI
InChIKey=JWAZRIHNYRIHIV-UHFFFAOYSA-N
InChI=1S/C10H8O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7,11H
| Molecular Formula | C10H8O |
| Molecular Weight | 144.1699 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
Overview
| CYP3A4 | CYP2C9 | CYP2D6 | hERG |
|---|---|---|---|
OverviewOther
| Other Inhibitor | Other Substrate | Other Inducer |
|---|---|---|
Drug as perpetrator​
| Target | Modality | Activity | Metabolite | Clinical evidence |
|---|---|---|---|---|
| yes [IC50 17 uM] | ||||
| yes |
Drug as victim
| Target | Modality | Activity | Metabolite | Clinical evidence |
|---|---|---|---|---|
| yes | ||||
| yes |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Evaluation of diazotized 4-amino-3,5-dinitrobenzoic acid (ADBA) as a new derivatizing reagent. | 2001 Sep |
|
| Comparison of advanced processes on the oxidation of acid orange 7 dye. | 2002 Aug |
|
| Modeling of the Acid Orange 7 anaerobic biodegradation. | 2003 |
|
| Identification and purification of sulfotransferases for 20-hydroxysteroid from the larval fat body of a fleshfly, Sarcophaga peregrina. | 2003 Aug |
|
| Use of chiral zwitterionic surfactants for enantiomeric resolutions by capillary electrophoresis. | 2003 Aug |
|
| Predictive value of comparative molecular field analysis modelling of naphthalene inhibition of human CYP2A6 and mouse CYP2A5 enzymes. | 2003 Aug |
|
| Altered expression of sulfotransferases, glucuronosyltransferases and mrp transporters in FVB/mrp1-/- mice. | 2003 Dec |
|
| Study of tropaeolin degradation by iron--proposition of a reaction mechanism. | 2003 Dec |
|
| Dissolution-aggregation behavior of water-soluble nanographites and their adsorptive characteristics for 2-naphthol in aqueous solutions. | 2003 Dec 1 |
|
| Reaction between naphthols and dimethyl acetylenedicarboxylate in the presence of phosphites. Synthesis of stable oxa-2 lambda 5-phosphaphenanthrenes, and benzochromene derivatives. | 2003 Feb 7 |
|
| Enantioselective oxidative biaryl coupling reactions catalyzed by 1,5-diazadecalin metal complexes: efficient formation of chiral functionalized BINOL derivatives. | 2003 Jul 11 |
|
| Effect-directed identification of oxygen and sulfur heterocycles as major polycyclic aromatic cytochrome P4501A-inducers in a contaminated sediment. | 2003 Jul 15 |
|
| Synthesis and evaluation of esters and carbamates to identify critical functional groups for esterase-specific metabolism. | 2003 Jul 31 |
|
| DNA damage in T- and B-lymphocytes and granulocytes in emission inspection and incineration workers exposed to polycyclic aromatic hydrocarbons. | 2003 Jul 8 |
|
| The application of HPLC-F and GC-MS to the analysis of selected hydroxy polycyclic hydrocarbons in two certified fish bile reference materials. | 2003 Jun |
|
| Boron-doped diamond microelectrodes for use in capillary electrophoresis with electrochemical detection. | 2003 Jun 1 |
|
| Carboxylations of alkali metal phenoxides with carbon dioxide. | 2003 Mar 7 |
|
| Effects of genetic polymorphisms in metabolic enzymes on the relationships between 8-hydroxydeoxyguanosine levels in human leukocytes and urinary 1-hydroxypyrene and 2-naphthol concentrations. | 2003 May |
|
| Electrophilic substitution of C60F18 into phenols: HF elimination between OH and a 1,3-shifted fluorine giving benzofurano[2',3':10,26]hexadecafluro[60]fullerene and derivatives. | 2003 May 21 |
|
| Measurement of pesticides and other toxicants in amniotic fluid as a potential biomarker of prenatal exposure: a validation study. | 2003 Nov |
|
| Urinary biomarkers of exposure to jet fuel (JP-8). | 2003 Nov |
|
| Pyran derivatives. Part XXI. Antiproliferative and cytotoxic properties of novel N-substituted 4-aminocoumarins, their benzo-fused derivatives, and some related 2-aminochromones. | 2003 Nov |
|
| Cytotoxic isolates of Helicobacter pylori from peptic ulcer diseases decrease K+-dependent ATPase activity in HeLa cells. | 2003 Nov 6 |
|
| Naphthalene--an environmental and occupational toxicant. | 2003 Oct |
|
| Synthesis of alpha-amino acids via asymmetric phase transfer-catalyzed alkylation of achiral nickel(II) complexes of glycine-derived Schiff bases. | 2003 Oct 22 |
|
| Arginine residues in the active site of human phenol sulfotransferase (SULT1A1). | 2003 Sep 19 |
|
| Photocatalytic degradation of wastewater pollutants: titanium dioxide mediated degradation of methyl orange and beta-naphthol orange. | 2003 Sep-Oct |
|
| Discoloration and mineralization of non-biodegradable azo dye Orange II by copper-doped TiO2 nanocatalysts. | 2004 |
|
| Effect of reverse micelles on the Rose Bengal-sensitized photo-oxidation of 1- and 2-hydroxynaphthalenes. | 2004 |
|
| Adsorption and biodegradation of azo dye in biofilm processes. | 2004 |
|
| Binary competitive adsorption of naphthalene compounds onto an aminated hypercrosslinked macroporous polymeric adsorbent. | 2004 |
|
| Albumin adducts of naphthalene metabolites as biomarkers of exposure to polycyclic aromatic hydrocarbons. | 2004 Jan |
|
| Urinary hydroxy-metabolites of naphthalene, phenanthrene and pyrene as markers of exposure to diesel exhaust. | 2004 Jan |
|
| Novel bentonite clay-based Fe-nanocomposite as a heterogeneous catalyst for photo-Fenton discoloration and mineralization of Orange II. | 2004 Jan 1 |
|
| 7-Hydroxynaphthalen-1-yl-urea and -amide antagonists of human vanilloid receptor 1. | 2004 Jan 19 |
|
| Effect of pH on adsolubilization of single and binary organic solutes into a cationic hydrocarbon surfactant adsorbed layer on silica. | 2004 Jul 15 |
|
| Urinary biomarkers in charcoal workers exposed to wood smoke in Bahia State, Brazil. | 2004 Jun |
|
| Treatment of orange II azo-dye by electrocoagulation (EC) technique in a continuous flow cell using sacrificial iron electrodes. | 2004 Jun 18 |
|
| Molecular imprinting made easy. | 2004 Jun 30 |
|
| Ruthenium-catalyzed cyclization of epoxide with a tethered alkyne: formation of ketene intermediates via oxygen transfer from epoxides to terminal alkynes. | 2004 Jun 9 |
|
| Simultaneous determination of 1- and 2-naphthol in human urine using on-line clean-up column-switching liquid chromatography-fluorescence detection. | 2004 Mar 5 |
|
| Naphthalene and its biomarkers as measures of occupational exposure to polycyclic aromatic hydrocarbons. | 2004 May |
|
| Influence of phenylalanines 77 and 138 on the stereospecificity of aryl sulfotransferase IV. | 2004 May |
|
| Application of ionic liquid halide nucleophilicity for the cleavage of ethers: a green protocol for the regeneration of phenols from ethers. | 2004 May 14 |
|
| Enantioselective O- and N-nitroso aldol synthesis of tin enolates. Isolation of three BINAP-silver complexes and their role in regio- and enantioselectivity. | 2004 May 5 |
|
| Differential pulse polarographic determination of lead in standard alloys and biological samples after separation and preconcentration with PAN. | 2004 May-Jun |
|
| Decolorization of orange II by catalytic oxidation using iron (III) phthalocyanine-tetrasulfonic acid. | 2004 Oct 18 |
|
| Synthesis and coordinating ability of an anionic cobaltabisdicarbollide ligand geometrically analogous to BINAP. | 2004 Oct 25 |
|
| Stress regulation of sulfotransferases in male rat liver. | 2004 Oct 8 |
|
| Controlling the regiospecific oxidation of aromatics via active site engineering of toluene para-monooxygenase of Ralstonia pickettii PKO1. | 2005 Jan 7 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Jul 05 22:50:17 UTC 2023
by
admin
on
Wed Jul 05 22:50:17 UTC 2023
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| Record UNII |
P2Z71CIK5H
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| Record Status |
Validated (UNII)
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| Record Version |
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| Classification Tree | Code System | Code | ||
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EPA PESTICIDE CODE |
10301
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NCI_THESAURUS |
C250
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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DTXSID5027061
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PRIMARY | |||
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135-19-3
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C81517
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M7739
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2-NAPHTHOL
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100000153158
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2044
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10432
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3370
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CHEMBL14126
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P2Z71CIK5H
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C028405
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SUB127015
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6812
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205-182-7
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8663
Created by
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| Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT | |||
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SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> METABOLITE |
IN VITRO
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
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