U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C12H12N2O2S
Molecular Weight 248.301
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DAPSONE

SMILES

NC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(N)C=C2

InChI

InChIKey=MQJKPEGWNLWLTK-UHFFFAOYSA-N
InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2

HIDE SMILES / InChI

Molecular Formula C12H12N2O2S
Molecular Weight 248.301
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Substance Class Chemical
Created
by admin
on Tue Mar 06 11:21:07 UTC 2018
Edited
by admin
on Tue Mar 06 11:21:07 UTC 2018
Record UNII
8W5C518302
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DAPSONE
EP   HSDB   INN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
USAN   INN  
Official Name English
DAPSONE [VANDF]
Common Name English
ACZONE
Brand Name English
DAPSONE [WHO-IP]
Common Name English
NSC-6091
Code English
DAPSONE [INN]
Common Name English
DAPSONE [USP]
Common Name English
4,4'-SULFONYLDIANILINE
Systematic Name English
DAPSONE [HSDB]
Common Name English
SULPHADIONE
Common Name English
DAPSONE [MART.]
Common Name English
NOVOPHONE
Common Name English
DAPSONUM [WHO-IP LATIN]
Common Name English
DAPSONE [EP]
Common Name English
J04BA02
Code English
DIAPHENYLSULFONE [JAN]
Common Name English
DIAPHENYLSULFONE
JAN  
Common Name English
BENZENAMINE, 4,4'-SULFONYLBIS-
Systematic Name English
DAPSONE [ORANGE BOOK]
Common Name English
DAPSONE [WHO-DD]
Common Name English
DAPSONE [MI]
Common Name English
DAPSONE [USP-RS]
Common Name English
NSC-6091D
Code English
DAPSONE [USAN]
Common Name English
SERVIDAPSON
Common Name English
Classification Tree Code System Code
NDF-RT N0000008053
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
WHO-VATC QD10AX05
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
WHO-ESSENTIAL MEDICINES LIST 6.2.3
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
WHO-ATC J04BA02
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
WHO-VATC QJ04BA02
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
WHO-ATC D10AX05
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
NDF-RT N0000175881
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
NDF-RT N0000008053
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
EPA PESTICIDE CODE 690107
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
LIVERTOX 264
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
Code System Code Type Description
HSDB
80-08-0
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY
MESH
D003622
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY
PUBCHEM
2955
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY SWITZERF
EVMPD
SUB06909MIG
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY
ChEMBL
CHEMBL1043
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY
CAS
80-08-0
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY
LactMed
80-08-0
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY
RXCUI
3108
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY RxNorm
ECHA (EC/EINECS)
201-248-4
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY
MERCK INDEX
M4092
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY Merck Index
INN
1676
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
DAPSONE
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY Description: A white or creamy white, crystalline powder; odourless. Solubility: Soluble in 7000 parts of water and in 30 parts of ethanol (~750 g/l) TS; soluble in acetone R.Category: Antileprotic. Storage: Dapsone should be kept in a tightly closed container, protected from light. Additional information: Even in the absence of light, Dapsone is gradually degraded on exposure to a humid atmosphere, thedecomposition being faster at higher temperatures.
WIKIPEDIA
DAPSONE
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY
DRUG BANK
DB00250
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY
NCI_THESAURUS
C415
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY
EPA CompTox
80-08-0
Created by admin on Tue Mar 06 11:21:07 UTC 2018 , Edited by admin on Tue Mar 06 11:21:07 UTC 2018
PRIMARY
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We have also shown recently that greater than 90% of dapsone hydroxylation in human liver microsomes is undertaken by cytochrome P4503A4
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Metabolite known for methaemoglobin formation in man.
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