DAPSONE HYDROXYLAMINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H12N2O3S
Molecular Weight	264.3
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DAPSONE HYDROXYLAMINE

Structure Search

SMILES

NC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(NO)C=C2

InChI

InChIKey=IYDSJDWESCGRKW-UHFFFAOYSA-N

InChI=1S/C12H12N2O3S/c13-9-1-5-11(6-2-9)18(16,17)12-7-3-10(14-15)4-8-12/h1-8,14-15H,13H2

HIDE SMILES / InChI

Molecular Formula	C12H12N2O3S
Molecular Weight	264.3
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

PubMed

Title	Date	PubMed
Formation and uptake of arylhydroxylamine-haptenated proteins in human dendritic cells.	2007 Apr	17220235

Substance Class	Chemical Created by `admin` on `Sat Dec 16 11:05:17 UTC 2023` Edited by `admin` on `Sat Dec 16 11:05:17 UTC 2023`
Record UNII	GS5815Z51W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DAPSONE HYDROXYLAMINE

Common Name

English

BENZENAMINE, 4-((4-AMINOPHENYL)SULFONYL)-N-HYDROXY-

Systematic Name

English

NSC-742234

Code

English

N-HYDROXY-4,4'-SULFONYLDI(ANILINE)

Systematic Name

English

N-HYDROXYDAPSONE

Common Name

English

4-(HYDROXYAMINO)-4'-AMINODIPHENYL SULFONE

Systematic Name

English

Code System Code Type Description

NSC

742234

Created by admin on Sat Dec 16 11:05:17 UTC 2023 , Edited by admin on Sat Dec 16 11:05:17 UTC 2023

PRIMARY

EPA CompTox

DTXSID30186361

Created by admin on Sat Dec 16 11:05:17 UTC 2023 , Edited by admin on Sat Dec 16 11:05:17 UTC 2023

PRIMARY

FDA UNII

GS5815Z51W

Created by admin on Sat Dec 16 11:05:17 UTC 2023 , Edited by admin on Sat Dec 16 11:05:17 UTC 2023

PRIMARY

PUBCHEM

65387

Created by admin on Sat Dec 16 11:05:17 UTC 2023 , Edited by admin on Sat Dec 16 11:05:17 UTC 2023

PRIMARY

CAS

32695-27-5

Created by admin on Sat Dec 16 11:05:17 UTC 2023 , Edited by admin on Sat Dec 16 11:05:17 UTC 2023

PRIMARY

Related Record Type Details


					8W5C518302

DAPSONE

METABOLITE -> PARENT

Comments:

We have also shown recently that greater than 90% of dapsone hydroxylation in human liver microsomes is undertaken by cytochrome P4503A4

Qualification:

URINE

Amount:


					8W5C518302

DAPSONE

PARENT -> METABOLITE TOXIC

Comments:

Metabolite known for methaemoglobin formation in man.

Amount: