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Details

Stereochemistry ACHIRAL
Molecular Formula C12H12N2O3S
Molecular Weight 264.3
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DAPSONE HYDROXYLAMINE

SMILES

NC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(NO)C=C2

InChI

InChIKey=IYDSJDWESCGRKW-UHFFFAOYSA-N
InChI=1S/C12H12N2O3S/c13-9-1-5-11(6-2-9)18(16,17)12-7-3-10(14-15)4-8-12/h1-8,14-15H,13H2

HIDE SMILES / InChI

Molecular Formula C12H12N2O3S
Molecular Weight 264.3
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Reduction of sulfamethoxazole and dapsone hydroxylamines by a microsomal enzyme system purified from pig liver and pig and human liver microsomes.
2005 May 27
Lipids versus proteins as major targets of pro-oxidant, direct-acting hemolytic agents.
2005 Nov
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:05:17 GMT 2023
Edited
by admin
on Sat Dec 16 11:05:17 GMT 2023
Record UNII
GS5815Z51W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DAPSONE HYDROXYLAMINE
Common Name English
BENZENAMINE, 4-((4-AMINOPHENYL)SULFONYL)-N-HYDROXY-
Systematic Name English
NSC-742234
Code English
N-HYDROXY-4,4'-SULFONYLDI(ANILINE)
Systematic Name English
N-HYDROXYDAPSONE
Common Name English
4-(HYDROXYAMINO)-4'-AMINODIPHENYL SULFONE
Systematic Name English
Code System Code Type Description
NSC
742234
Created by admin on Sat Dec 16 11:05:17 GMT 2023 , Edited by admin on Sat Dec 16 11:05:17 GMT 2023
PRIMARY
EPA CompTox
DTXSID30186361
Created by admin on Sat Dec 16 11:05:17 GMT 2023 , Edited by admin on Sat Dec 16 11:05:17 GMT 2023
PRIMARY
FDA UNII
GS5815Z51W
Created by admin on Sat Dec 16 11:05:17 GMT 2023 , Edited by admin on Sat Dec 16 11:05:17 GMT 2023
PRIMARY
PUBCHEM
65387
Created by admin on Sat Dec 16 11:05:17 GMT 2023 , Edited by admin on Sat Dec 16 11:05:17 GMT 2023
PRIMARY
CAS
32695-27-5
Created by admin on Sat Dec 16 11:05:17 GMT 2023 , Edited by admin on Sat Dec 16 11:05:17 GMT 2023
PRIMARY
Related Record Type Details
METABOLITE -> PARENT
We have also shown recently that greater than 90% of dapsone hydroxylation in human liver microsomes is undertaken by cytochrome P4503A4
URINE
PARENT -> METABOLITE TOXIC
Metabolite known for methaemoglobin formation in man.