Details
Stereochemistry | ACHIRAL |
Molecular Formula | C9H12NO5PS |
Molecular Weight | 277.234 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COP(=S)(OC)OC1=CC(C)=C(C=C1)[N+]([O-])=O
InChI
InChIKey=ZNOLGFHPUIJIMJ-UHFFFAOYSA-N
InChI=1S/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3
Molecular Formula | C9H12NO5PS |
Molecular Weight | 277.234 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
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Studies on the present status of insecticides resistance on mosquitoes using the diagnostic dosages in El-Fayium Governorate, a spot area of malaria in Egypt. | 2001 Apr |
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Negative correlations between resistance to three organophosphate insecticides and productivity within a natural population of Drosophila melanogaster (Diptera: Drosophilidae). | 2002 Dec |
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Long-term effectiveness of grain protectants and structural treatments against Liposcelis decolor (Pearman) (Psocoptera: Liposcelididae), a pest of stored products. | 2002 Dec |
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Multilevel effects of sublethal fenitrothion exposure in Chironomus riparius Mg. (Diptera, Chironomidae) larvae. | 2002 Dec |
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Use of chronic tests with Daphnia magna for examination of diluted river water. | 2002 Nov |
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Activated transformations of organophosphorus insecticides in the case of non-AChE inhibitory oxons. | 2002 Nov |
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Validation of an SPME method, using PDMS, PA, PDMS-DVB, and CW-DVB SPME fiber coatings, for analysis of organophosphorus insecticides in natural waters. | 2002 Nov |
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Genetic basis of cross-resistance to three organophosphate insecticides in Drosophila melanogaster (Diptera: Drosophilidae). | 2002 Oct |
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Cadmium-fenitrothion interaction in the spider Pardosa lugubris and the fruit fly Drosophila melanogaster. | 2002 Oct |
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Interaction of organophosphate pesticides and related compounds with the androgen receptor. | 2003 Apr |
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The multidrug resistance-associated protein 1 transports methoxychlor and protects the seminiferous epithelium from injury. | 2003 Apr 30 |
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Determination of organophosphorus aromatic nitro insecticides and p-nitrophenol by microbial-cell respiratory activity. | 2003 Aug 1 |
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Metabolism of fenitrothion and conjugation of 3-methyl-4-nitrophenol in tomato plant (Lycopersicon esculentum). | 2003 Aug 13 |
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Study of the mechanism of Flavobacterium sp. for hydrolyzing organophosphate pesticides. | 2003 Dec |
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Contribution of metabolites to mutagenicity during anaerobic biodegradation of fenitrothion. | 2003 Jan |
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SBSE-GC-ECD/FPD in the analysis of pesticide residues in Passiflora alata Dryander herbal teas. | 2003 Jan 1 |
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Fast supercritical fluid extraction and high-resolution gas chromatography with electron-capture and flame photometric detection for multiresidue screening of organochlorine and organophosphorus pesticides in Brazil's medicinal plants. | 2003 Jan 24 |
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Biodisposition and biochemical effects of a new phosphoramidate series in rat tissues. | 2003 Jun |
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Insecticide susceptibility tests of Anopheles minimus s.l., Aedes aegypti, Aedes albopictus, and Culex quinquefasciatus in northern Thailand. | 2003 Mar |
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Resistance of Aedes aegypti to organophosphates in several municipalities in the State of Rio de Janeiro and Espírito Santo, Brazil. | 2003 Mar |
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Effect of the combined treatment of insecticides and an attractant for the control of Phloeotribus scarabaeoides, a pest of Olea europea. | 2003 Mar |
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Rapid multiresidue determination of organochlorine and organophosphorus compounds in human serum by solid-phase extraction and gas chromatography coupled to tandem mass spectrometry. | 2003 May |
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Distribution of multiple pesticide residues in apple segments after home processing. | 2003 Nov |
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Determination of impurities in pesticides and their degradation products formed during the wine-making process by solid-phase extraction and gas chromatography with detection by electron impact mass spectrometry. I. Vinclozoline, procymidone and fenitrothion. | 2004 |
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Fenitrothion-induced structural and functional perturbations in the yolk lipoproteins of the shrimp Macrobrachium borellii. | 2004 Apr |
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Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. | 2004 Apr |
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Investigation of acute toxicity of fenitrothion on peppered corydoras (Corydoras paleatus) (Jenyns, 1842). | 2004 Aug |
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Acceleration of nucleophilic attack on an organophosphorothioate neurotoxin, fenitrothion, by reactive counterion cationic micelles. Regioselectivity as a probe of substrate orientation within the micelle. | 2004 Aug 3 |
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Cu(II)-Mediated decomposition of phosphorothionate P=S pesticides. Billion-fold acceleration of the methanolysis of fenitrothion promoted by a simple Cu(II)-ligand system. | 2004 Aug 7 |
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Changes in the hemodynamic state of patients with acute lethal organophosphate poisoning. | 2004 Feb |
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Changes in leucine transport activity in Chironomus riparius larvae after short-term exposure to potassium dichromate and fenitrothion. | 2004 Feb |
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Field-incurred fenitrothion residues in kakis: comparison of individual fruits, composite samples, and peeled and cooked fruits. | 2004 Feb 25 |
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Effects of sublethal fenitrothion ingestion on cholinesterase inhibition, standard metabolism, thermal preference, and prey-capture ability in the Australian central bearded dragon (Pogona vitticeps, Agamidae). | 2004 Jan |
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[Monitoring of the insecticidal resistance of main malaria vectors in Uzbekistan]. | 2004 Jan-Mar |
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The effect of plasmapheresis on plasma cholinesterase levels in a patient with organophosphate poisoning. | 2004 Jul |
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Late administration of pralidoxime in organophosphate (fenitrothion) poisoning. | 2004 Jul |
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Determination of organophosphorus pesticides using membrane-assisted solvent extraction combined with large volume injection-gas chromatography-mass spectrometric detection. | 2004 Jun 25 |
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Biodegradation and bioaccumulation of fenitrothion in rat liver. | 2004 Mar |
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Effect of potassium dichromate and fenitrothion on hemoglobins of Chironomus riparius Mg. (Diptera, Chironomidae) larvae: potential biomarker of environmental monitoring. | 2004 Mar |
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Estimation of estrogenic and antiestrogenic activities of selected pesticides by MCF-7 cell proliferation assay. | 2004 May |
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Ranking of chemical substances based on the Japanese Pollutant Release and Transfer Register using partial order theory and random linear extensions. | 2004 May |
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Influence of the application of sewage sludge on the degradation of pesticides in the soil. | 2004 Nov |
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Photocatalytic removal of fenitrothion in pure and natural waters by photo-Fenton reaction. | 2004 Nov |
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Fenitrothion-induced changes in lipids of rats. | 2004 Nov |
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Density-independent population projection trajectories of chromosome-substituted lines resistant and susceptible to organophosphate insecticides in Drosophila melanogaster. | 2004 Nov 24 |
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Resistance and synergistic effects of insecticides in Bactrocera dorsalis (Diptera: Tephritidae) in Taiwan. | 2004 Oct |
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Zn2+-catalyzed methanolysis of phosphate triesters: a process for catalytic degradation of the organophosphorus pesticides paraoxon and fenitrothion. | 2004 Oct 18 |
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Anogenital distance in human male and female newborns: a descriptive, cross-sectional study. | 2004 Sep 13 |
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Evaluation of a compact bench top immunoassay analyzer for automatic and near continuous monitoring of a sample for environmental contaminants. | 2004 Sep 15 |
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Lack of evidence for endocrine disrupting effects in rats exposed to fenitrothion in utero and from weaning to maturation. | 2005 Jan 5 |
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 16 17:53:54 UTC 2022
by
admin
on
Fri Dec 16 17:53:54 UTC 2022
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Record UNII |
W8M4X3Y7ZY
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Record Status |
Validated (UNII)
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Record Version |
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Name | Type | Language | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Systematic Name | English | ||
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Systematic Name | English | ||
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Common Name | English |
Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C471
Created by
admin on Fri Dec 16 17:53:54 UTC 2022 , Edited by admin on Fri Dec 16 17:53:54 UTC 2022
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EPA PESTICIDE CODE |
105901
Created by
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Code System | Code | Type | Description | ||
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34757
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PRIMARY | |||
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1590
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PRIMARY | |||
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204-524-2
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PRIMARY | |||
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31200
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PRIMARY | |||
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fenitrothion
Created by
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122-14-5
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PRIMARY | |||
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DTXSID4032613
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FENITROTHION
Created by
admin on Fri Dec 16 17:53:54 UTC 2022 , Edited by admin on Fri Dec 16 17:53:54 UTC 2022
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D005278
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PRIMARY | |||
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M5277
Created by
admin on Fri Dec 16 17:53:54 UTC 2022 , Edited by admin on Fri Dec 16 17:53:54 UTC 2022
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PRIMARY | Merck Index | ||
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CHEMBL347698
Created by
admin on Fri Dec 16 17:53:54 UTC 2022 , Edited by admin on Fri Dec 16 17:53:54 UTC 2022
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PRIMARY | |||
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C65655
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PRIMARY | |||
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W8M4X3Y7ZY
Created by
admin on Fri Dec 16 17:53:54 UTC 2022 , Edited by admin on Fri Dec 16 17:53:54 UTC 2022
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PRIMARY |
Related Record | Type | Details | ||
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METABOLIC ENZYME -> INHIBITOR |
Fenitrothion inhibited CYP1A1/2 activities more than 90%.
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METABOLIC ENZYME -> INHIBITOR |
Screening of potential CYP2B6 inhibitions illustrates that CYP2B6 activity was extensively inhibited by all tested organophosphate pesticides. Inhibition percentages were 100% with fenitrothion.
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METABOLIC ENZYME -> INHIBITOR |
CYP2C9 activity was extensively inhibited (more than 90% inhibition) by organophosphorus insecticides fenitrothion
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METABOLIC ENZYME -> INHIBITOR |
Fenitrothion inhibited CYP1A1/2 activities more than 90%.
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METABOLIC ENZYME -> INHIBITOR |
inhibitions between 59 and 84% were
observed with fenitrothion
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METABOLIC ENZYME -> INHIBITOR |
Extensive inhibitions of CYP2A6-associated activity (94–98%) were observed with fenitrothion,
|