Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H12NO5PS |
| Molecular Weight | 277.234 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COP(=S)(OC)OC1=CC=C(C(C)=C1)[N+]([O-])=O
InChI
InChIKey=ZNOLGFHPUIJIMJ-UHFFFAOYSA-N
InChI=1S/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3
| Molecular Formula | C9H12NO5PS |
| Molecular Weight | 277.234 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Lack of evidence for endocrine disrupting effects in rats exposed to fenitrothion in utero and from weaning to maturation. | 2005-01-05 |
|
| Density-independent population projection trajectories of chromosome-substituted lines resistant and susceptible to organophosphate insecticides in Drosophila melanogaster. | 2004-11-24 |
|
| Influence of the application of sewage sludge on the degradation of pesticides in the soil. | 2004-11 |
|
| Photocatalytic removal of fenitrothion in pure and natural waters by photo-Fenton reaction. | 2004-11 |
|
| Fenitrothion-induced changes in lipids of rats. | 2004-11 |
|
| Zn2+-catalyzed methanolysis of phosphate triesters: a process for catalytic degradation of the organophosphorus pesticides paraoxon and fenitrothion. | 2004-10-18 |
|
| Resistance and synergistic effects of insecticides in Bactrocera dorsalis (Diptera: Tephritidae) in Taiwan. | 2004-10 |
|
| Evaluation of a compact bench top immunoassay analyzer for automatic and near continuous monitoring of a sample for environmental contaminants. | 2004-09-15 |
|
| Anogenital distance in human male and female newborns: a descriptive, cross-sectional study. | 2004-09-13 |
|
| Cu(II)-Mediated decomposition of phosphorothionate P=S pesticides. Billion-fold acceleration of the methanolysis of fenitrothion promoted by a simple Cu(II)-ligand system. | 2004-08-07 |
|
| Acceleration of nucleophilic attack on an organophosphorothioate neurotoxin, fenitrothion, by reactive counterion cationic micelles. Regioselectivity as a probe of substrate orientation within the micelle. | 2004-08-03 |
|
| Investigation of acute toxicity of fenitrothion on peppered corydoras (Corydoras paleatus) (Jenyns, 1842). | 2004-08 |
|
| The effect of plasmapheresis on plasma cholinesterase levels in a patient with organophosphate poisoning. | 2004-07 |
|
| Late administration of pralidoxime in organophosphate (fenitrothion) poisoning. | 2004-07 |
|
| Determination of organophosphorus pesticides using membrane-assisted solvent extraction combined with large volume injection-gas chromatography-mass spectrometric detection. | 2004-06-25 |
|
| Estimation of estrogenic and antiestrogenic activities of selected pesticides by MCF-7 cell proliferation assay. | 2004-05 |
|
| Ranking of chemical substances based on the Japanese Pollutant Release and Transfer Register using partial order theory and random linear extensions. | 2004-05 |
|
| Fenitrothion-induced structural and functional perturbations in the yolk lipoproteins of the shrimp Macrobrachium borellii. | 2004-04 |
|
| Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. | 2004-04 |
|
| [Monitoring of the insecticidal resistance of main malaria vectors in Uzbekistan]. | 2004-03-27 |
|
| Biodegradation and bioaccumulation of fenitrothion in rat liver. | 2004-03 |
|
| Effect of potassium dichromate and fenitrothion on hemoglobins of Chironomus riparius Mg. (Diptera, Chironomidae) larvae: potential biomarker of environmental monitoring. | 2004-03 |
|
| Field-incurred fenitrothion residues in kakis: comparison of individual fruits, composite samples, and peeled and cooked fruits. | 2004-02-25 |
|
| Changes in the hemodynamic state of patients with acute lethal organophosphate poisoning. | 2004-02 |
|
| Changes in leucine transport activity in Chironomus riparius larvae after short-term exposure to potassium dichromate and fenitrothion. | 2004-02 |
|
| An amino acid substitution attributable to insecticide-insensitivity of acetylcholinesterase in a Japanese encephalitis vector mosquito, Culex tritaeniorhynchus. | 2004-01-16 |
|
| Effects of sublethal fenitrothion ingestion on cholinesterase inhibition, standard metabolism, thermal preference, and prey-capture ability in the Australian central bearded dragon (Pogona vitticeps, Agamidae). | 2004-01 |
|
| Determination of impurities in pesticides and their degradation products formed during the wine-making process by solid-phase extraction and gas chromatography with detection by electron impact mass spectrometry. I. Vinclozoline, procymidone and fenitrothion. | 2004 |
|
| Study of the mechanism of Flavobacterium sp. for hydrolyzing organophosphate pesticides. | 2003-12 |
|
| Control trial of Lutzomyia longipalpis s.l. in the Island of Margarita, Venezuela. | 2003-12 |
|
| Distribution of multiple pesticide residues in apple segments after home processing. | 2003-11 |
|
| p-Coumaroylnoradrenaline, a novel plant metabolite implicated in tomato defense against pathogens. | 2003-10-31 |
|
| [A case of mixed poisoning by organophosphate and methanol]. | 2003-10 |
|
| Metabolism of fenitrothion and conjugation of 3-methyl-4-nitrophenol in tomato plant (Lycopersicon esculentum). | 2003-08-13 |
|
| Determination of organophosphorus aromatic nitro insecticides and p-nitrophenol by microbial-cell respiratory activity. | 2003-08-01 |
|
| Resistance of Aedes aegypti from the state of São Paulo, Brazil, to organophosphates insecticides. | 2003-07 |
|
| Biodisposition and biochemical effects of a new phosphoramidate series in rat tissues. | 2003-06 |
|
| Rapid multiresidue determination of organochlorine and organophosphorus compounds in human serum by solid-phase extraction and gas chromatography coupled to tandem mass spectrometry. | 2003-05 |
|
| The multidrug resistance-associated protein 1 transports methoxychlor and protects the seminiferous epithelium from injury. | 2003-04-30 |
|
| Headspace solid-phase microextraction in combination with gas chromatography-mass spectrometry for the rapid screening of organophosphorus insecticide residues in strawberries and cherries. | 2003-04-18 |
|
| [Practical analysis of toxic substances useful for clinical toxicology--6--Organophosphates]. | 2003-04 |
|
| Interaction of organophosphate pesticides and related compounds with the androgen receptor. | 2003-04 |
|
| Insecticide susceptibility tests of Anopheles minimus s.l., Aedes aegypti, Aedes albopictus, and Culex quinquefasciatus in northern Thailand. | 2003-03 |
|
| Resistance of Aedes aegypti to organophosphates in several municipalities in the State of Rio de Janeiro and Espírito Santo, Brazil. | 2003-03 |
|
| Effect of the combined treatment of insecticides and an attractant for the control of Phloeotribus scarabaeoides, a pest of Olea europea. | 2003-03 |
|
| Fenitrothion: toxicokinetics and toxicologic evaluation in human volunteers. | 2003-03 |
|
| Fast supercritical fluid extraction and high-resolution gas chromatography with electron-capture and flame photometric detection for multiresidue screening of organochlorine and organophosphorus pesticides in Brazil's medicinal plants. | 2003-01-24 |
|
| Contribution of metabolites to mutagenicity during anaerobic biodegradation of fenitrothion. | 2003-01 |
|
| [An experimental tool essential for the evaluation of insecticides: the testing huts]. | 2002-11 |
|
| Studies on the present status of insecticides resistance on mosquitoes using the diagnostic dosages in El-Fayium Governorate, a spot area of malaria in Egypt. | 2001-04 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:05:57 GMT 2025
by
admin
on
Mon Mar 31 18:05:57 GMT 2025
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| Record UNII |
W8M4X3Y7ZY
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| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Preferred Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Systematic Name | English | ||
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Systematic Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C471
Created by
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EPA PESTICIDE CODE |
105901
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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34757
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PRIMARY | |||
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1590
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PRIMARY | |||
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204-524-2
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PRIMARY | |||
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31200
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PRIMARY | |||
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fenitrothion
Created by
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PRIMARY | |||
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122-14-5
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DTXSID4032613
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FENITROTHION
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D005278
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m5277
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PRIMARY | Merck Index | ||
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CHEMBL347698
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300000023722
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C65655
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W8M4X3Y7ZY
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
METABOLIC ENZYME -> INHIBITOR |
Fenitrothion inhibited CYP1A1/2 activities more than 90%
|
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METABOLIC ENZYME -> INHIBITOR |
Screening of potential CYP2B6 inhibitions illustrates that CYP2B6 activity was extensively inhibited by all tested organophosphate pesticides. Inhibition percentages were 100% with fenitrothion.
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METABOLIC ENZYME -> INHIBITOR |
CYP2C9 activity was extensively inhibited (more than 90% inhibition) by organophosphorus insecticides fenitrothion
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METABOLIC ENZYME -> INHIBITOR |
Fenitrothion inhibited CYP1A1/2 activities more than 90%.
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METABOLIC ENZYME -> INHIBITOR |
inhibitions between 59 and 84% were
observed with fenitrothion
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METABOLIC ENZYME -> INHIBITOR |
Extensive inhibitions of CYP2A6-associated activity (94–98%) were observed with fenitrothion,
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