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Details

Stereochemistry ACHIRAL
Molecular Formula C10H14NO5PS
Molecular Weight 291.2621
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PARATHION

SMILES

CCOP(=S)(OCC)Oc1ccc(cc1)N(=O)=O

InChI

InChIKey=LCCNCVORNKJIRZ-UHFFFAOYSA-N
InChI=1S/C10H14NO5PS/c1-3-14-17(18,15-4-2)16-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C10H14NO5PS
Molecular Weight 291.2621
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Suxamethonium sensitivity.
1971 Jul 6
Pathways of microbial metabolism of parathion.
1976 Jan
Effect of phenobarbitol pretreatment on regeneration of plasma cholinesterase activity inhibited by parathion or dichlorovos.
1982 Jan-Feb
Changes in toxicity of DDVP, DFP, and parathion in rats under cold environment.
1982 Nov
The effects of organophosphate-induced cholinergic stimulation on the antibody response to sheep erythrocytes in inbred mice.
1983 Apr
Prolonged toxicity with intermediate syndrome after combined parathion and methyl parathion poisoning.
1992
Interaction of structurally diverse pesticides with the human MDR1 gene product P-glycoprotein.
1996 Nov
Modeling of sorption and biodegradation of parathion and its metabolite paraoxon in soil.
2003 Nov-Dec
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.
2003 Oct
Intraclonal variability in Daphnia acetylcholinesterase activity: the implications for its applicability as a biomarker.
2003 Sep
Determination of malathion and diazinon resistance by sequencing the Md alpha E7 gene from Guatemala, Colombia, Manhattan, and Thailand housefly (Musca domestica L.) strains.
2004 Apr
Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells.
2004 Apr
Cardiac responses of Pacific oyster Crassostrea gigas to agents modulating cholinergic function.
2004 Dec
Block of neuronal nicotinic acetylcholine receptors by organophosphate insecticides.
2004 Dec
Mutations of acetylcholinesterase which confer insecticide resistance in Drosophila melanogaster populations.
2004 Feb 5
Acetylcholinesterase alterations reveal the fitness cost of mutations conferring insecticide resistance.
2004 Feb 6
Time course of brain cholinesterase inhibition and recovery following acute and subacute azinphosmethyl, parathion and carbaryl exposure in the goldfish (Carassius auratus).
2004 Mar
Stress regulation of sulfotransferases in male rat liver.
2004 Oct 8
Organophosphorus insecticides induce airway hyperreactivity by decreasing neuronal M2 muscarinic receptor function independent of acetylcholinesterase inhibition.
2005 Jan
Malathion bioactivation in the human liver: the contribution of different cytochrome p450 isoforms.
2005 Mar
High-level expression of recombinant human paraoxonase 1 Q in silkworm larvae (Bombyx mori).
2006 Aug
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.
2006 Nov
Organophosphate insecticides target the serotonergic system in developing rat brain regions: disparate effects of diazinon and parathion at doses spanning the threshold for cholinesterase inhibition.
2006 Oct
Pesticides and adult respiratory outcomes in the agricultural health study.
2006 Sep
Recent emergence of insensitive acetylcholinesterase in Chinese populations of the mosquito Culex pipiens (Diptera: Culicidae).
2006 Sep
Enhanced nucleophilic reactivity of hydroxamate ions in some novel micellar systems for the cleavage of parathion.
2006 Sep 15
Paradoxical effect of salbutamol in a model of acute organophosphates intoxication in guinea pigs: role of substance P release.
2007 Apr
Gene expression signature of parathion-transformed human breast epithelial cells.
2007 May
Gene and protein expressions induced by 17beta-estradiol and parathion in cultured breast epithelial cells.
2007 May-Jun
Cancer genes induced by malathion and parathion in the presence of estrogen in breast cells.
2008 Feb
Sorption of hydrophobic organic compounds (HOC) in rapeseed oil bodies.
2008 Feb
Pesticide use and adult-onset asthma among male farmers in the Agricultural Health Study.
2009 Dec
A concentration addition model for the activation of the constitutive androstane receptor by xenobiotic mixtures.
2009 Jan
Consumption of a high-fat diet in adulthood ameliorates the effects of neonatal parathion exposure on acetylcholine systems in rat brain regions.
2009 Jun
A high-throughput method for assessing chemical toxicity using a Caenorhabditis elegans reproduction assay.
2010 Jun 1
Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.
2011 Feb 27
Prior or coinstantaneous oral exposure to environmental immunosuppressive agents aggravates mite allergen-induced atopic dermatitis-like immunoreaction in NC/Nga mice.
2011 Nov 18
Induction of plasma acetylcholinesterase activity in mice challenged with organophosphorus poisons.
2011 Sep 1
DNA methylation alterations in response to pesticide exposure in vitro.
2012 Aug
Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity.
2012 Aug 16
Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer risk.
2012 Feb
Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran.
2012 Feb 5
Role of regulatory T cells in the induction of atopic dermatitis by immunosuppressive chemicals.
2012 Sep 18
Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs.
2013 Apr 15
Immunotoxicity in mice induced by short-term exposure to methoxychlor, parathion, or piperonyl butoxide.
2013 Apr-Jun
Chlorpyrifos-, diisopropylphosphorofluoridate-, and parathion-induced behavioral and oxidative stress effects: are they mediated by analogous mechanisms of action?
2013 Jan
Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity.
2013 Jun
Hypothyroidism and pesticide use among male private pesticide applicators in the agricultural health study.
2013 Oct
Pesticide exposure and inherited variants in vitamin d pathway genes in relation to prostate cancer.
2013 Sep
Comparative study on short- and long-term behavioral consequences of organophosphate exposure: relationship to AChE mRNA expression.
2014 Jan
Patents
Substance Class Chemical
Created
by admin
on Sat Jun 26 09:07:28 UTC 2021
Edited
by admin
on Sat Jun 26 09:07:28 UTC 2021
Record UNII
61G466064D
Record Status Validated (UNII)
Record Version
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Name Type Language
PARATHION
HSDB   ISO   MART.   MI   WHO-DD  
Common Name English
E-605
Code English
PARATHION [MI]
Common Name English
PARATHION [IARC]
Common Name English
NSC-8933
Code English
O,O-DIETHYL O-4-NITROPHENYL PHOSPHOROTHIOATE
Systematic Name English
PARATHION [WHO-DD]
Common Name English
DIETHYL-P-NITROPHENYL MONOTHIOPHOSPHATE
Common Name English
PARATHION [MART.]
Common Name English
THIOPHOS
Common Name English
PARATHION [ISO]
Common Name English
O,O-DIETHYL O-(4-NITROPHENYL) PHOSPHOROTHIOATE
Systematic Name English
PARATHION [HSDB]
Common Name English
PHOSPHOROTHIOIC ACID O,O-DIETHYL O-(4-NITROPHENYL) ESTER
Systematic Name English
Classification Tree Code System Code
IARC Parathion
EPA PESTICIDE CODE 57501
Created by admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
Code System Code Type Description
MESH
D010278
Created by admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
PRIMARY
EVMPD
SUB14775MIG
Created by admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
PRIMARY
CAS
56-38-2
Created by admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
PRIMARY
EPA CompTox
56-38-2
Created by admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
PRIMARY
HSDB
197
Created by admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
PRIMARY
PUBCHEM
991
Created by admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
PRIMARY
MERCK INDEX
M8407
Created by admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
PRIMARY Merck Index
WIKIPEDIA
PARATHION
Created by admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
PRIMARY
FDA UNII
61G466064D
Created by admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
PRIMARY
ECHA (EC/EINECS)
200-271-7
Created by admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
PRIMARY
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