Details
Stereochemistry | ACHIRAL |
Molecular Formula | C10H14NO5PS |
Molecular Weight | 291.2621 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCOP(=S)(OCC)Oc1ccc(cc1)N(=O)=O
InChI
InChIKey=LCCNCVORNKJIRZ-UHFFFAOYSA-N
InChI=1S/C10H14NO5PS/c1-3-14-17(18,15-4-2)16-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3
Molecular Formula | C10H14NO5PS |
Molecular Weight | 291.2621 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
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Suxamethonium sensitivity. | 1971 Jul 6 |
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Pathways of microbial metabolism of parathion. | 1976 Jan |
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Effect of phenobarbitol pretreatment on regeneration of plasma cholinesterase activity inhibited by parathion or dichlorovos. | 1982 Jan-Feb |
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Changes in toxicity of DDVP, DFP, and parathion in rats under cold environment. | 1982 Nov |
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The effects of organophosphate-induced cholinergic stimulation on the antibody response to sheep erythrocytes in inbred mice. | 1983 Apr |
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Prolonged toxicity with intermediate syndrome after combined parathion and methyl parathion poisoning. | 1992 |
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Interaction of structurally diverse pesticides with the human MDR1 gene product P-glycoprotein. | 1996 Nov |
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Modeling of sorption and biodegradation of parathion and its metabolite paraoxon in soil. | 2003 Nov-Dec |
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Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. | 2003 Oct |
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Intraclonal variability in Daphnia acetylcholinesterase activity: the implications for its applicability as a biomarker. | 2003 Sep |
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Determination of malathion and diazinon resistance by sequencing the Md alpha E7 gene from Guatemala, Colombia, Manhattan, and Thailand housefly (Musca domestica L.) strains. | 2004 Apr |
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Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. | 2004 Apr |
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Cardiac responses of Pacific oyster Crassostrea gigas to agents modulating cholinergic function. | 2004 Dec |
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Block of neuronal nicotinic acetylcholine receptors by organophosphate insecticides. | 2004 Dec |
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Mutations of acetylcholinesterase which confer insecticide resistance in Drosophila melanogaster populations. | 2004 Feb 5 |
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Acetylcholinesterase alterations reveal the fitness cost of mutations conferring insecticide resistance. | 2004 Feb 6 |
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Time course of brain cholinesterase inhibition and recovery following acute and subacute azinphosmethyl, parathion and carbaryl exposure in the goldfish (Carassius auratus). | 2004 Mar |
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Stress regulation of sulfotransferases in male rat liver. | 2004 Oct 8 |
|
Organophosphorus insecticides induce airway hyperreactivity by decreasing neuronal M2 muscarinic receptor function independent of acetylcholinesterase inhibition. | 2005 Jan |
|
Malathion bioactivation in the human liver: the contribution of different cytochrome p450 isoforms. | 2005 Mar |
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High-level expression of recombinant human paraoxonase 1 Q in silkworm larvae (Bombyx mori). | 2006 Aug |
|
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006 Nov |
|
Organophosphate insecticides target the serotonergic system in developing rat brain regions: disparate effects of diazinon and parathion at doses spanning the threshold for cholinesterase inhibition. | 2006 Oct |
|
Pesticides and adult respiratory outcomes in the agricultural health study. | 2006 Sep |
|
Recent emergence of insensitive acetylcholinesterase in Chinese populations of the mosquito Culex pipiens (Diptera: Culicidae). | 2006 Sep |
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Enhanced nucleophilic reactivity of hydroxamate ions in some novel micellar systems for the cleavage of parathion. | 2006 Sep 15 |
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Paradoxical effect of salbutamol in a model of acute organophosphates intoxication in guinea pigs: role of substance P release. | 2007 Apr |
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Gene expression signature of parathion-transformed human breast epithelial cells. | 2007 May |
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Gene and protein expressions induced by 17beta-estradiol and parathion in cultured breast epithelial cells. | 2007 May-Jun |
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Cancer genes induced by malathion and parathion in the presence of estrogen in breast cells. | 2008 Feb |
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Sorption of hydrophobic organic compounds (HOC) in rapeseed oil bodies. | 2008 Feb |
|
Pesticide use and adult-onset asthma among male farmers in the Agricultural Health Study. | 2009 Dec |
|
A concentration addition model for the activation of the constitutive androstane receptor by xenobiotic mixtures. | 2009 Jan |
|
Consumption of a high-fat diet in adulthood ameliorates the effects of neonatal parathion exposure on acetylcholine systems in rat brain regions. | 2009 Jun |
|
A high-throughput method for assessing chemical toxicity using a Caenorhabditis elegans reproduction assay. | 2010 Jun 1 |
|
Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays. | 2011 Feb 27 |
|
Prior or coinstantaneous oral exposure to environmental immunosuppressive agents aggravates mite allergen-induced atopic dermatitis-like immunoreaction in NC/Nga mice. | 2011 Nov 18 |
|
Induction of plasma acetylcholinesterase activity in mice challenged with organophosphorus poisons. | 2011 Sep 1 |
|
DNA methylation alterations in response to pesticide exposure in vitro. | 2012 Aug |
|
Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity. | 2012 Aug 16 |
|
Genetic variation in nucleotide excision repair pathway genes, pesticide exposure and prostate cancer risk. | 2012 Feb |
|
Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran. | 2012 Feb 5 |
|
Role of regulatory T cells in the induction of atopic dermatitis by immunosuppressive chemicals. | 2012 Sep 18 |
|
Macrophage TNF-α mediates parathion-induced airway hyperreactivity in guinea pigs. | 2013 Apr 15 |
|
Immunotoxicity in mice induced by short-term exposure to methoxychlor, parathion, or piperonyl butoxide. | 2013 Apr-Jun |
|
Chlorpyrifos-, diisopropylphosphorofluoridate-, and parathion-induced behavioral and oxidative stress effects: are they mediated by analogous mechanisms of action? | 2013 Jan |
|
Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity. | 2013 Jun |
|
Hypothyroidism and pesticide use among male private pesticide applicators in the agricultural health study. | 2013 Oct |
|
Pesticide exposure and inherited variants in vitamin d pathway genes in relation to prostate cancer. | 2013 Sep |
|
Comparative study on short- and long-term behavioral consequences of organophosphate exposure: relationship to AChE mRNA expression. | 2014 Jan |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Jun 26 09:07:28 UTC 2021
by
admin
on
Sat Jun 26 09:07:28 UTC 2021
|
Record UNII |
61G466064D
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Record Status |
Validated (UNII)
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Record Version |
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-
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Classification Tree | Code System | Code | ||
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IARC | Parathion | ||
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EPA PESTICIDE CODE |
57501
Created by
admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
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Code System | Code | Type | Description | ||
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D010278
Created by
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PRIMARY | |||
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SUB14775MIG
Created by
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PRIMARY | |||
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56-38-2
Created by
admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
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PRIMARY | |||
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56-38-2
Created by
admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
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PRIMARY | |||
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197
Created by
admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
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PRIMARY | |||
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991
Created by
admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
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PRIMARY | |||
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M8407
Created by
admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
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PRIMARY | Merck Index | ||
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PARATHION
Created by
admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
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61G466064D
Created by
admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
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200-271-7
Created by
admin on Sat Jun 26 09:07:28 UTC 2021 , Edited by admin on Sat Jun 26 09:07:28 UTC 2021
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PRIMARY |
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METABOLITE -> PARENT |