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Details

Stereochemistry ACHIRAL
Molecular Formula C8H10NO5PS
Molecular Weight 263.2089
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PARATHION-METHYL

SMILES

COP(=S)(OC)Oc1ccc(cc1)N(=O)=O

InChI

InChIKey=RLBIQVVOMOPOHC-UHFFFAOYSA-N
InChI=1S/C8H10NO5PS/c1-12-15(16,13-2)14-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3

HIDE SMILES / InChI

Molecular Formula C8H10NO5PS
Molecular Weight 263.2089
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Inhibition of acetylcholinesterase and butyrylcholinesterase by the organophosphorus insecticide methylparathion in the central nervous system of the golden hamster (Mesocricetus auratus).
1991
Prolonged toxicity with intermediate syndrome after combined parathion and methyl parathion poisoning.
1992
Differential toxicities of organophosphate and carbamate insecticides in the nestling European starling (Sturnus vulgaris).
2000 Aug
Cholinergic and noncholinergic brain biomarkers of insecticide exposure and effects.
2000 May
Analysis of organophosphorus pesticides in honeybee by liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry.
2001 Aug
Absorption, distribution, metabolism and excretion of daily oral doses of [14C]methyl parathion in hens.
2001 Dec 15
Solid-phase microextraction method for the determination of atrazine and four organophosphorus pesticides in soil samples by gas chromatography.
2001 Dec 21
Optimizing microwave-assisted solvent extraction (MASE) of pesticides from soil.
2001 Jan
Inhibition and recovery of maternal and fetal cholinesterase enzyme activity following a single cutaneous dose of methyl parathion and diazinon, alone and in combination, in pregnant rats.
2001 Jul-Aug
The role of glutathione S-transferases in the detoxification of some organophosphorus insecticides in larvae and pupae of the yellow mealworm, Tenebrio molitor (Coleoptera: Tenebrionidae).
2001 Jun
Inhibition of cholinesterase enzymes following a single dermal dose of chlorpyrifos and methyl parathion, alone and in combination, in pregnant rats.
2001 Jun 8
Methyl parathion induced alterations in monoaminergic system of developing rat pups.
2001 Mar
A modified extraction and clean-up procedure for the detection and determination of parathion-methyl and chlorpyrifos residues in tea.
2001 May
Cytochrome P450 2B (CYP2B)-mediated activation of methyl-parathion in rat brain extracts.
2001 Oct 15
Sex-related response to organophosphorus and carbamate insecticides in adult Oriental fruit moth, Grapholita molesta.
2001 Sep
Effects of atrazine on acetylcholinesterase activity in midges (Chironomus tentans) exposed to organophosphorus insecticides.
2001 Sep
Different quantitation approaches for xenobiotics in human urine samples by liquid chromatography/electrospray tandem mass spectrometry.
2002
Mechanisms of resistance to organophosphates in Tetranychus urticae (Acari: Tetranychidae) from Greece.
2002 Apr
Biological monitoring of combined exposure to organophosphates and pyrethroids.
2002 Aug 5
Simple determination of 22 organophosphorous pesticides in human blood using headspace solid-phase microextraction and gas chromatography with mass spectrometric detection.
2002 Jan
Increased toxicity to invertebrates associated with a mixture of atrazine and organophosphate insecticides.
2002 Jul
Determination of pesticide residues in coconut water by liquid-liquid extraction and gas chromatography with electron-capture plus thermionic specific detection and solid-phase extraction and high-performance liquid chromatography with ultraviolet detection.
2002 May 31
Determination of pesticide residues in nonfatty foods by supercritical fluid extraction and gas chromatography/mass spectrometry: collaborative study.
2002 Sep-Oct
Fluorescence polarization immunoassay based on a monoclonal antibody for the detection of the organophosphorus pesticide parathion-methyl.
2003 Feb 26
Fast supercritical fluid extraction and high-resolution gas chromatography with electron-capture and flame photometric detection for multiresidue screening of organochlorine and organophosphorus pesticides in Brazil's medicinal plants.
2003 Jan 24
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.
2003 Oct
Block of neuronal nicotinic acetylcholine receptors by organophosphate insecticides.
2004 Dec
What contributes to the combined effect of a complex mixture?
2004 Dec 1
Methyl parathion interaction with human and bovine serum albumin.
2004 Feb 28
Metabolical effects of Folidol 600 on the neotropical freshwater fish matrinxã, Brycon cephalus.
2004 Jun
Biotransformation of methyl parathion by glutathione S-transferases.
2004 Jun
Effects of methyl parathion (o,o-dimethyl o-4-nitrophenyl phosphorothioate) on rat sperm morphology and sperm count, but not fertility, are associated with decreased ascorbic acid level in the testis.
2005 Dec 7
Short- and long-term response of sunflower to airborne bromoxynil-octanoate under controlled and field conditions.
2005 Jul
Evaluation of sublethal biomarkers in Litopenaeus vannamei on foodborne exposure to methyl parathion.
2005 Sep
Evaluation of performance of a commercial monoclonal antibody-based fenitrothion immunoassay and application to residual analysis in fruit samples.
2006 Jan
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line.
2006 Nov 10
Sonocatalytic degradation of methyl parathion in the presence of nanometer and ordinary anatase titanium dioxide catalysts and comparison of their sonocatalytic abilities.
2006 Sep
Alteration of neurotrophins in the hippocampus and cerebral cortex of young rats exposed to chlorpyrifos and methyl parathion.
2007 Dec
Interaction of insecticides with mammalian P-glycoprotein and their effect on its transport function.
2007 Jul
Cutinase inhibition by means of insecticidal organophosphates and carbamates. 3. Oxidation of phosphorothionates by chloroperoxidase from Caldariomyces fumago.
2007 Oct 3
Multi-residue determination of pesticides in water using multi-walled carbon nanotubes solid-phase extraction and gas chromatography-mass spectrometry.
2007 Sep 21
Subacute effects of methyl parathion on antioxidant defense systems and lipid peroxidation in rats.
2008 Aug
Monitoring of organophosphorus pesticide residues in vegetables of agricultural area in Venezuela.
2008 Oct
Organophosphorus pesticides enhance the genotoxicity of benzo(a)pyrene by modulating its metabolism.
2009 Dec 1
Mercaptobenzothiazole-on-gold organic phase biosensor systems: 1. Enhanced organosphosphate pesticide determination.
2009 Feb
The effects of selenium on oxidative stress biomarkers in the freshwater characid fish matrinxã, Brycon cephalus (Günther, 1869) exposed to organophosphate insecticide Folisuper 600 BR (methyl parathion).
2009 Jan
Methyl-parathion decreases sperm function and fertilization capacity after targeting spermatocytes and maturing spermatozoa.
2009 Jul 15
Organophosphorus pesticide residues in milled rice (Oryza sativa) on the Chinese market and dietary risk assessment.
2009 Mar
A transposable class I composite transposon carrying mph (methyl parathion hydrolase) from Pseudomonas sp. strain WBC-3.
2009 Mar
Development of square wave voltammetry method for the assessment of organophosphorus compound impact on the cholinesterase of Pheretima with 2,6-dichloroindophenol as a redox indicator.
2009 Sep
Patents
Substance Class Chemical
Created
by admin
on Sat Jun 26 04:05:05 UTC 2021
Edited
by admin
on Sat Jun 26 04:05:05 UTC 2021
Record UNII
41BCL2O91D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PARATHION-METHYL
HSDB   ISO  
Common Name English
GEARPHOS
Brand Name English
BAY E 601
Brand Name English
DIMETHYL P-NITROPHENYL THIONOPHOSPHATE
Common Name English
O,O-DIMETHYL O-(4-NITROPHENYL) PHOSPHOROTHIOATE
Systematic Name English
PHOSPHOROTHIOIC ACID, O,O-DIMETHYL O-(4-NITROPHENYL) ESTER
Common Name English
PARATHION-METHYL [ISO]
Common Name English
METHYL PARATHION [MI]
Common Name English
FOLIDOL M
Brand Name English
DIMETHYL 4-NITROPHENYL PHOSPHOROTHIONATE
Common Name English
BAY-11405
Code English
METACIDE
Brand Name English
PARATHION-METHYL [HSDB]
Common Name English
METHYL PARATHION
MI  
Common Name English
METAFOS
Brand Name English
METACID
Brand Name English
O,O-DIMETHYL O-(4-NITROPHENYL) THIOPHOSPHATE
Systematic Name English
METHYL PARATHION [IARC]
Common Name English
METRON
Brand Name English
DIMETHYL PARATHION
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 53501
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
Code System Code Type Description
MESH
D008743
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
MERCK INDEX
M7451
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY Merck Index
PUBCHEM
4130
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
HSDB
1168
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
ECHA (EC/EINECS)
206-050-1
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
FDA UNII
41BCL2O91D
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
EPA CompTox
298-00-0
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
CAS
298-00-0
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
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