U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C8H10NO5PS
Molecular Weight 263.207
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PARATHION-METHYL

SMILES

COP(=S)(OC)OC1=CC=C(C=C1)[N+]([O-])=O

InChI

InChIKey=RLBIQVVOMOPOHC-UHFFFAOYSA-N
InChI=1S/C8H10NO5PS/c1-12-15(16,13-2)14-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3

HIDE SMILES / InChI

Molecular Formula C8H10NO5PS
Molecular Weight 263.207
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Inhibition of acetylcholinesterase and butyrylcholinesterase by the organophosphorus insecticide methylparathion in the central nervous system of the golden hamster (Mesocricetus auratus).
1991
In vivo and in vitro acetylcholinesterase inhibition by metacid-50 and carbaryl in Channa punctatus under natural field condition.
1992 Mar
A bi-enzymatic whole cell conductometric biosensor for heavy metal ions and pesticides detection in water samples.
2005 Aug 15
Effects of methyl parathion (o,o-dimethyl o-4-nitrophenyl phosphorothioate) on rat sperm morphology and sperm count, but not fertility, are associated with decreased ascorbic acid level in the testis.
2005 Dec 7
Short- and long-term response of sunflower to airborne bromoxynil-octanoate under controlled and field conditions.
2005 Jul
Assessment of pesticide residues in two arable soils from the semi-arid and subtropical regions of China.
2005 Oct
Acetylcholinesterase sensor based on screen-printed carbon electrode modified with prussian blue.
2005 Oct
Evaluation of sublethal biomarkers in Litopenaeus vannamei on foodborne exposure to methyl parathion.
2005 Sep
An organophosphate insecticide methyl parathion (o- o- dimethyl o-4-nitrophenyl phosphorothioate) induces cytotoxic damage and tubular atrophy in the testis despite elevated testosterone level in the rat.
2006 Aug
Degradation of organophosphorus neurotoxicity in SY5Y neuroblastoma cells by organophosphorus hydrolase (OPH).
2006 Aug
Evaluation of performance of a commercial monoclonal antibody-based fenitrothion immunoassay and application to residual analysis in fruit samples.
2006 Jan
Motor functions but not learning and memory are impaired upon repeated exposure to sub-lethal doses of methyl parathion.
2006 Jul
[Isolation and identification of a bacterial strain JS018 capable of degrading several kinds of organophosphate pesticides].
2006 Jun
Oxidative stress biomarkers in the freshwater characid fish, Brycon cephalus, exposed to organophosphorus insecticide Folisuper 600 (methyl parathion).
2006 Jun
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line.
2006 Nov 10
Sonocatalytic degradation of methyl parathion in the presence of nanometer and ordinary anatase titanium dioxide catalysts and comparison of their sonocatalytic abilities.
2006 Sep
Nucleophilic substitution of phosphorothionate ester pesticides with bisulfide (HS-) and polysulfides (S(n)2-).
2006 Sep 1
Effects of seed coatings with thiamethoxam on germination and flea beetle control in flax.
2007
Acute organophosphate poisoning in university hospital emergency room patients.
2007
Volatilization of parathion and chlorothalonil from a potato crop simulated by the PEARL model.
2007 Apr 1
Alteration of neurotrophins in the hippocampus and cerebral cortex of young rats exposed to chlorpyrifos and methyl parathion.
2007 Dec
Multienzyme inhibition assay for residue analysis of insecticidal organophosphates and carbamates.
2007 Dec 26
Lack of cross-resistance to indoxacarb in insecticide-resistant Spodoptera frugiperda (Lepidoptera: Noctuidae) and Plutella xylostella (Lepidoptera: Yponomeutidae).
2007 Jan
Interaction of insecticides with mammalian P-glycoprotein and their effect on its transport function.
2007 Jul
Isolation of a chlorpyrifos-degrading bacterium, Sphingomonas sp. strain Dsp-2, and cloning of the mpd gene.
2007 Mar
[Determination of organic phosphorus pesticide residues in scallion by gas chromatography coupled with microwave clean-up].
2007 May
Effects of methyl parathion on Chasmagnathus granulatus hepatopancreas: protective role of sesamol.
2007 May
Enzyme-linked immunosorbent assays for the insecticide fenitrothion. Influence of hapten conformation and sample matrix on assay performance.
2007 May 22
Hapten design and indirect competitive immunoassay for parathion determination: correlation with molecular modeling and principal component analysis.
2007 May 22
Altered muscarinic acetylcholine receptor subtype binding in neonatal rat brain following exposure to chlorpyrifos or methyl parathion.
2007 Nov
Cutinase inhibition by means of insecticidal organophosphates and carbamates. 3. Oxidation of phosphorothionates by chloroperoxidase from Caldariomyces fumago.
2007 Oct 3
Multi-residue determination of pesticides in water using multi-walled carbon nanotubes solid-phase extraction and gas chromatography-mass spectrometry.
2007 Sep 21
The effect of parathion-methyl and antidotes on parotid and pancreatic glands: a pilot experimental study.
2007 Sep-Oct
Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.
2008 Apr
Subacute effects of methyl parathion on antioxidant defense systems and lipid peroxidation in rats.
2008 Aug
Volatilisation and competing processes computed for a pesticide applied to plants in a wind tunnel system.
2008 Jun
Direct and indirect effects of pollutants on algae and algivorous ciliates in an aquatic indoor microcosm.
2008 Jun 23
Optimization of separation and detection conditions for the multiresidue analysis of pesticides in grapes by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry.
2008 May 9
Applicability of cloud point extraction coupled with microwave-assisted back-extraction to the determination of organophosphorous pesticides in human urine by gas chromatography with flame photometry detection.
2008 Nov 30
Monitoring of organophosphorus pesticide residues in vegetables of agricultural area in Venezuela.
2008 Oct
Organophosphorus pesticides enhance the genotoxicity of benzo(a)pyrene by modulating its metabolism.
2009 Dec 1
Mercaptobenzothiazole-on-gold organic phase biosensor systems: 1. Enhanced organosphosphate pesticide determination.
2009 Feb
The effects of selenium on oxidative stress biomarkers in the freshwater characid fish matrinxã, Brycon cephalus (Günther, 1869) exposed to organophosphate insecticide Folisuper 600 BR (methyl parathion).
2009 Jan
Identification and characterization of chlorpyrifos-methyl and 3,5,6-trichloro-2-pyridinol degrading Burkholderia sp. strain KR100.
2009 Jul
Methyl-parathion decreases sperm function and fertilization capacity after targeting spermatocytes and maturing spermatozoa.
2009 Jul 15
Organophosphorus pesticide residues in milled rice (Oryza sativa) on the Chinese market and dietary risk assessment.
2009 Mar
The potential role of cAMP as a pollution biomarker of terrestrial environments using the land snail Eobania vermiculata: correlation with lysosomal membrane stability.
2009 Sep
Development of square wave voltammetry method for the assessment of organophosphorus compound impact on the cholinesterase of Pheretima with 2,6-dichloroindophenol as a redox indicator.
2009 Sep
Comparing the inhibitory effects of five protoxicant organophosphates (azinphos-methyl, parathion-methyl, chlorpyriphos-methyl, methamidophos and diazinon) on the spontaneously beating auricle of Sparus aurata: an in vitro study.
2009 Sep 14
Blood gene expression markers to detect and distinguish target organ toxicity.
2010 Feb
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 01:31:30 GMT 2023
Edited
by admin
on Sat Dec 16 01:31:30 GMT 2023
Record UNII
41BCL2O91D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PARATHION-METHYL
HSDB   ISO  
Common Name English
GEARPHOS
Brand Name English
BAY E 601
Brand Name English
DIMETHYL P-NITROPHENYL THIONOPHOSPHATE
Common Name English
O,O-DIMETHYL O-(4-NITROPHENYL) PHOSPHOROTHIOATE
Systematic Name English
PHOSPHOROTHIOIC ACID, O,O-DIMETHYL O-(4-NITROPHENYL) ESTER
Common Name English
PARATHION-METHYL [ISO]
Common Name English
METHYL PARATHION [MI]
Common Name English
FOLIDOL M
Brand Name English
DIMETHYL 4-NITROPHENYL PHOSPHOROTHIONATE
Common Name English
BAY-11405
Code English
METACIDE
Brand Name English
PARATHION-METHYL [HSDB]
Common Name English
METHYL PARATHION
MI  
Common Name English
METAFOS
Brand Name English
METACID
Brand Name English
O,O-DIMETHYL O-(4-NITROPHENYL) THIOPHOSPHATE
Systematic Name English
METHYL PARATHION [IARC]
Common Name English
METRON
Brand Name English
DIMETHYL PARATHION
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 53501
Created by admin on Sat Dec 16 01:31:30 GMT 2023 , Edited by admin on Sat Dec 16 01:31:30 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C163677
Created by admin on Sat Dec 16 01:31:30 GMT 2023 , Edited by admin on Sat Dec 16 01:31:30 GMT 2023
PRIMARY
CHEBI
38746
Created by admin on Sat Dec 16 01:31:30 GMT 2023 , Edited by admin on Sat Dec 16 01:31:30 GMT 2023
PRIMARY
MESH
D008743
Created by admin on Sat Dec 16 01:31:30 GMT 2023 , Edited by admin on Sat Dec 16 01:31:30 GMT 2023
PRIMARY
ALANWOOD
parathion-methyl
Created by admin on Sat Dec 16 01:31:30 GMT 2023 , Edited by admin on Sat Dec 16 01:31:30 GMT 2023
PRIMARY
WIKIPEDIA
Parathion methyl
Created by admin on Sat Dec 16 01:31:30 GMT 2023 , Edited by admin on Sat Dec 16 01:31:30 GMT 2023
PRIMARY
MERCK INDEX
m7451
Created by admin on Sat Dec 16 01:31:30 GMT 2023 , Edited by admin on Sat Dec 16 01:31:30 GMT 2023
PRIMARY Merck Index
PUBCHEM
4130
Created by admin on Sat Dec 16 01:31:30 GMT 2023 , Edited by admin on Sat Dec 16 01:31:30 GMT 2023
PRIMARY
HSDB
1168
Created by admin on Sat Dec 16 01:31:30 GMT 2023 , Edited by admin on Sat Dec 16 01:31:30 GMT 2023
PRIMARY
ECHA (EC/EINECS)
206-050-1
Created by admin on Sat Dec 16 01:31:30 GMT 2023 , Edited by admin on Sat Dec 16 01:31:30 GMT 2023
PRIMARY
FDA UNII
41BCL2O91D
Created by admin on Sat Dec 16 01:31:30 GMT 2023 , Edited by admin on Sat Dec 16 01:31:30 GMT 2023
PRIMARY
EPA CompTox
DTXSID1020855
Created by admin on Sat Dec 16 01:31:30 GMT 2023 , Edited by admin on Sat Dec 16 01:31:30 GMT 2023
PRIMARY
CAS
298-00-0
Created by admin on Sat Dec 16 01:31:30 GMT 2023 , Edited by admin on Sat Dec 16 01:31:30 GMT 2023
PRIMARY
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