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Details

Stereochemistry ACHIRAL
Molecular Formula C8H10NO5PS
Molecular Weight 263.207
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PARATHION-METHYL

SMILES

COP(=S)(OC)OC1=CC=C(C=C1)[N+]([O-])=O

InChI

InChIKey=RLBIQVVOMOPOHC-UHFFFAOYSA-N
InChI=1S/C8H10NO5PS/c1-12-15(16,13-2)14-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3

HIDE SMILES / InChI

Molecular Formula C8H10NO5PS
Molecular Weight 263.207
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Prolonged toxicity with intermediate syndrome after combined parathion and methyl parathion poisoning.
1992
Solid-phase microextraction method for the determination of atrazine and four organophosphorus pesticides in soil samples by gas chromatography.
2001 Dec 21
Cytochrome P450 2B (CYP2B)-mediated activation of methyl-parathion in rat brain extracts.
2001 Oct 15
Sex-related response to organophosphorus and carbamate insecticides in adult Oriental fruit moth, Grapholita molesta.
2001 Sep
Different quantitation approaches for xenobiotics in human urine samples by liquid chromatography/electrospray tandem mass spectrometry.
2002
Mechanisms of resistance to organophosphates in Tetranychus urticae (Acari: Tetranychidae) from Greece.
2002 Apr
Biological monitoring of combined exposure to organophosphates and pyrethroids.
2002 Aug 5
Simple determination of 22 organophosphorous pesticides in human blood using headspace solid-phase microextraction and gas chromatography with mass spectrometric detection.
2002 Jan
Increased toxicity to invertebrates associated with a mixture of atrazine and organophosphate insecticides.
2002 Jul
Determination of pesticide residues in coconut water by liquid-liquid extraction and gas chromatography with electron-capture plus thermionic specific detection and solid-phase extraction and high-performance liquid chromatography with ultraviolet detection.
2002 May 31
Determination of pesticide residues in nonfatty foods by supercritical fluid extraction and gas chromatography/mass spectrometry: collaborative study.
2002 Sep-Oct
Differential modulation of muscarinic receptors in the rat brain by repeated exposure to methyl parathion.
2003 Dec
The effects of repeated oral exposures to methyl parathion on rat brain cholinesterase and muscarinic receptors during postnatal development.
2003 Dec
Fluorescence polarization immunoassay based on a monoclonal antibody for the detection of the organophosphorus pesticide parathion-methyl.
2003 Feb 26
Effects of chronic dermal exposure to nonlethal doses of methyl parathion on brain regional acetylcholinesterase and muscarinic cholinergic receptors in female rats.
2003 Jan 1
Fast supercritical fluid extraction and high-resolution gas chromatography with electron-capture and flame photometric detection for multiresidue screening of organochlorine and organophosphorus pesticides in Brazil's medicinal plants.
2003 Jan 24
Pesticide volatilization from soil: lysimeter measurements versus predictions of European registration models.
2003 Jul-Aug
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.
2003 Oct
Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells.
2004 Apr
Block of neuronal nicotinic acetylcholine receptors by organophosphate insecticides.
2004 Dec
Methyl parathion interaction with human and bovine serum albumin.
2004 Feb 28
Metabolical effects of Folidol 600 on the neotropical freshwater fish matrinxã, Brycon cephalus.
2004 Jun
Crystallization and preliminary X-ray studies of methyl parathion hydrolase from Pseudomonas sp. WBC-3.
2004 May
Pesticide volatilization from plants: improvement of the PEC model PELMO based on a boundary-layer concept.
2004 May 15
Methyl parathion increases neuronal activities in the rat locus coeruleus.
2004 Nov-Dec
Sorption and detoxification of toxic compounds by a bifunctional organoclay.
2004 Sep-Oct
Effects of methyl parathion (o,o-dimethyl o-4-nitrophenyl phosphorothioate) on rat sperm morphology and sperm count, but not fertility, are associated with decreased ascorbic acid level in the testis.
2005 Dec 7
Assessment of pesticide residues in two arable soils from the semi-arid and subtropical regions of China.
2005 Oct
An organophosphate insecticide methyl parathion (o- o- dimethyl o-4-nitrophenyl phosphorothioate) induces cytotoxic damage and tubular atrophy in the testis despite elevated testosterone level in the rat.
2006 Aug
Degradation of organophosphorus neurotoxicity in SY5Y neuroblastoma cells by organophosphorus hydrolase (OPH).
2006 Aug
Evaluation of performance of a commercial monoclonal antibody-based fenitrothion immunoassay and application to residual analysis in fruit samples.
2006 Jan
Motor functions but not learning and memory are impaired upon repeated exposure to sub-lethal doses of methyl parathion.
2006 Jul
[Isolation and identification of a bacterial strain JS018 capable of degrading several kinds of organophosphate pesticides].
2006 Jun
Oxidative stress biomarkers in the freshwater characid fish, Brycon cephalus, exposed to organophosphorus insecticide Folisuper 600 (methyl parathion).
2006 Jun
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line.
2006 Nov 10
Nucleophilic substitution of phosphorothionate ester pesticides with bisulfide (HS-) and polysulfides (S(n)2-).
2006 Sep 1
Alteration of neurotrophins in the hippocampus and cerebral cortex of young rats exposed to chlorpyrifos and methyl parathion.
2007 Dec
Effects of methyl parathion on Chasmagnathus granulatus hepatopancreas: protective role of sesamol.
2007 May
Enzyme-linked immunosorbent assays for the insecticide fenitrothion. Influence of hapten conformation and sample matrix on assay performance.
2007 May 22
Subacute effects of methyl parathion on antioxidant defense systems and lipid peroxidation in rats.
2008 Aug
Effects of model organophosphorous pesticides on DNA damage and proliferation of HepG2 cells.
2008 Jun
Direct and indirect effects of pollutants on algae and algivorous ciliates in an aquatic indoor microcosm.
2008 Jun 23
Monitoring of organophosphorus pesticide residues in vegetables of agricultural area in Venezuela.
2008 Oct
High-performance thin-layer chromatographic analysis of selected organophosphorous pesticide residues in tea.
2008 Sep-Oct
Mercaptobenzothiazole-on-gold organic phase biosensor systems: 1. Enhanced organosphosphate pesticide determination.
2009 Feb
The effects of selenium on oxidative stress biomarkers in the freshwater characid fish matrinxã, Brycon cephalus (Günther, 1869) exposed to organophosphate insecticide Folisuper 600 BR (methyl parathion).
2009 Jan
Identification and characterization of chlorpyrifos-methyl and 3,5,6-trichloro-2-pyridinol degrading Burkholderia sp. strain KR100.
2009 Jul
Methyl-parathion decreases sperm function and fertilization capacity after targeting spermatocytes and maturing spermatozoa.
2009 Jul 15
A transposable class I composite transposon carrying mph (methyl parathion hydrolase) from Pseudomonas sp. strain WBC-3.
2009 Mar
Repeated developmental exposure to chlorpyrifos and methyl parathion causes persistent alterations in nicotinic acetylcholine subunit mRNA expression with chlorpyrifos altering dopamine metabolite levels.
2009 Mar-Apr
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 20:53:35 GMT 2025
Edited
by admin
on Mon Mar 31 20:53:35 GMT 2025
Record UNII
41BCL2O91D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
METHYL PARATHION
MI  
Preferred Name English
PARATHION-METHYL
HSDB   ISO  
Common Name English
GEARPHOS
Brand Name English
BAY E 601
Brand Name English
DIMETHYL P-NITROPHENYL THIONOPHOSPHATE
Common Name English
O,O-DIMETHYL O-(4-NITROPHENYL) PHOSPHOROTHIOATE
Systematic Name English
PHOSPHOROTHIOIC ACID, O,O-DIMETHYL O-(4-NITROPHENYL) ESTER
Common Name English
PARATHION-METHYL [ISO]
Common Name English
METHYL PARATHION [MI]
Common Name English
FOLIDOL M
Brand Name English
DIMETHYL 4-NITROPHENYL PHOSPHOROTHIONATE
Common Name English
BAY-11405
Code English
METACIDE
Brand Name English
PARATHION-METHYL [HSDB]
Common Name English
METAFOS
Brand Name English
METACID
Brand Name English
O,O-DIMETHYL O-(4-NITROPHENYL) THIOPHOSPHATE
Systematic Name English
METHYL PARATHION [IARC]
Common Name English
METRON
Brand Name English
DIMETHYL PARATHION
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 53501
Created by admin on Mon Mar 31 20:53:35 GMT 2025 , Edited by admin on Mon Mar 31 20:53:35 GMT 2025
Code System Code Type Description
NCI_THESAURUS
C163677
Created by admin on Mon Mar 31 20:53:35 GMT 2025 , Edited by admin on Mon Mar 31 20:53:35 GMT 2025
PRIMARY
CHEBI
38746
Created by admin on Mon Mar 31 20:53:35 GMT 2025 , Edited by admin on Mon Mar 31 20:53:35 GMT 2025
PRIMARY
MESH
D008743
Created by admin on Mon Mar 31 20:53:35 GMT 2025 , Edited by admin on Mon Mar 31 20:53:35 GMT 2025
PRIMARY
ALANWOOD
parathion-methyl
Created by admin on Mon Mar 31 20:53:35 GMT 2025 , Edited by admin on Mon Mar 31 20:53:35 GMT 2025
PRIMARY
WIKIPEDIA
Parathion methyl
Created by admin on Mon Mar 31 20:53:35 GMT 2025 , Edited by admin on Mon Mar 31 20:53:35 GMT 2025
PRIMARY
MERCK INDEX
m7451
Created by admin on Mon Mar 31 20:53:35 GMT 2025 , Edited by admin on Mon Mar 31 20:53:35 GMT 2025
PRIMARY Merck Index
PUBCHEM
4130
Created by admin on Mon Mar 31 20:53:35 GMT 2025 , Edited by admin on Mon Mar 31 20:53:35 GMT 2025
PRIMARY
HSDB
1168
Created by admin on Mon Mar 31 20:53:35 GMT 2025 , Edited by admin on Mon Mar 31 20:53:35 GMT 2025
PRIMARY
ECHA (EC/EINECS)
206-050-1
Created by admin on Mon Mar 31 20:53:35 GMT 2025 , Edited by admin on Mon Mar 31 20:53:35 GMT 2025
PRIMARY
FDA UNII
41BCL2O91D
Created by admin on Mon Mar 31 20:53:35 GMT 2025 , Edited by admin on Mon Mar 31 20:53:35 GMT 2025
PRIMARY
EPA CompTox
DTXSID1020855
Created by admin on Mon Mar 31 20:53:35 GMT 2025 , Edited by admin on Mon Mar 31 20:53:35 GMT 2025
PRIMARY
CAS
298-00-0
Created by admin on Mon Mar 31 20:53:35 GMT 2025 , Edited by admin on Mon Mar 31 20:53:35 GMT 2025
PRIMARY
Related Record Type Details
METABOLIC ENZYME -> SUBSTRATE
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