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Details

Stereochemistry ACHIRAL
Molecular Formula C8H10NO5PS
Molecular Weight 263.2089
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PARATHION-METHYL

SMILES

COP(=S)(OC)Oc1ccc(cc1)N(=O)=O

InChI

InChIKey=RLBIQVVOMOPOHC-UHFFFAOYSA-N
InChI=1S/C8H10NO5PS/c1-12-15(16,13-2)14-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3

HIDE SMILES / InChI

Molecular Formula C8H10NO5PS
Molecular Weight 263.2089
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Cholinergic and noncholinergic brain biomarkers of insecticide exposure and effects.
2000 May
Absorption, distribution, metabolism and excretion of daily oral doses of [14C]methyl parathion in hens.
2001 Dec 15
Solid-phase microextraction method for the determination of atrazine and four organophosphorus pesticides in soil samples by gas chromatography.
2001 Dec 21
Optimizing microwave-assisted solvent extraction (MASE) of pesticides from soil.
2001 Jan
Inhibition and recovery of maternal and fetal cholinesterase enzyme activity following a single cutaneous dose of methyl parathion and diazinon, alone and in combination, in pregnant rats.
2001 Jul-Aug
The role of glutathione S-transferases in the detoxification of some organophosphorus insecticides in larvae and pupae of the yellow mealworm, Tenebrio molitor (Coleoptera: Tenebrionidae).
2001 Jun
Inhibition of cholinesterase enzymes following a single dermal dose of chlorpyrifos and methyl parathion, alone and in combination, in pregnant rats.
2001 Jun 8
Methyl parathion induced alterations in monoaminergic system of developing rat pups.
2001 Mar
A modified extraction and clean-up procedure for the detection and determination of parathion-methyl and chlorpyrifos residues in tea.
2001 May
Differential modulation of muscarinic receptors in the rat brain by repeated exposure to methyl parathion.
2003 Dec
Pesticide volatilization from soil: lysimeter measurements versus predictions of European registration models.
2003 Jul-Aug
Acetylcholinesterase (AChE) electrodes based on gelatin and chitosan matrices for the pesticide detection.
2004
Determination of impurities in pesticides and their degradation products formed during the wine-making process by solid-phase extraction and gas chromatography with detection by electron ionization mass spectrometry. II. Bromopropylate, trichlorphon, parathion-methyl and tebuconazole.
2004
Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells.
2004 Apr
Methyl parathion interaction with human and bovine serum albumin.
2004 Feb 28
Biotransformation of methyl parathion by glutathione S-transferases.
2004 Jun
Determination of organophosphorus pesticides using membrane-assisted solvent extraction combined with large volume injection-gas chromatography-mass spectrometric detection.
2004 Jun 25
Crystallization and preliminary X-ray studies of methyl parathion hydrolase from Pseudomonas sp. WBC-3.
2004 May
Pesticide volatilization from plants: improvement of the PEC model PELMO based on a boundary-layer concept.
2004 May 15
A bi-enzymatic whole cell conductometric biosensor for heavy metal ions and pesticides detection in water samples.
2005 Aug 15
An organophosphate insecticide methyl parathion (o- o- dimethyl o-4-nitrophenyl phosphorothioate) induces cytotoxic damage and tubular atrophy in the testis despite elevated testosterone level in the rat.
2006 Aug
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line.
2006 Nov 10
Sonocatalytic degradation of methyl parathion in the presence of nanometer and ordinary anatase titanium dioxide catalysts and comparison of their sonocatalytic abilities.
2006 Sep
Acute organophosphate poisoning in university hospital emergency room patients.
2007
Multienzyme inhibition assay for residue analysis of insecticidal organophosphates and carbamates.
2007 Dec 26
Effects of methyl parathion on Chasmagnathus granulatus hepatopancreas: protective role of sesamol.
2007 May
Enzyme-linked immunosorbent assays for the insecticide fenitrothion. Influence of hapten conformation and sample matrix on assay performance.
2007 May 22
Multi-residue determination of pesticides in water using multi-walled carbon nanotubes solid-phase extraction and gas chromatography-mass spectrometry.
2007 Sep 21
Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.
2008 Apr
Subacute effects of methyl parathion on antioxidant defense systems and lipid peroxidation in rats.
2008 Aug
Effects of model organophosphorous pesticides on DNA damage and proliferation of HepG2 cells.
2008 Jun
High-performance thin-layer chromatographic analysis of selected organophosphorous pesticide residues in tea.
2008 Sep-Oct
The effects of selenium on oxidative stress biomarkers in the freshwater characid fish matrinxã, Brycon cephalus (Günther, 1869) exposed to organophosphate insecticide Folisuper 600 BR (methyl parathion).
2009 Jan
The potential role of cAMP as a pollution biomarker of terrestrial environments using the land snail Eobania vermiculata: correlation with lysosomal membrane stability.
2009 Sep
Patents
Substance Class Chemical
Created
by admin
on Sat Jun 26 04:05:05 UTC 2021
Edited
by admin
on Sat Jun 26 04:05:05 UTC 2021
Record UNII
41BCL2O91D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PARATHION-METHYL
HSDB   ISO  
Common Name English
GEARPHOS
Brand Name English
BAY E 601
Brand Name English
DIMETHYL P-NITROPHENYL THIONOPHOSPHATE
Common Name English
O,O-DIMETHYL O-(4-NITROPHENYL) PHOSPHOROTHIOATE
Systematic Name English
PHOSPHOROTHIOIC ACID, O,O-DIMETHYL O-(4-NITROPHENYL) ESTER
Common Name English
PARATHION-METHYL [ISO]
Common Name English
METHYL PARATHION [MI]
Common Name English
FOLIDOL M
Brand Name English
DIMETHYL 4-NITROPHENYL PHOSPHOROTHIONATE
Common Name English
BAY-11405
Code English
METACIDE
Brand Name English
PARATHION-METHYL [HSDB]
Common Name English
METHYL PARATHION
MI  
Common Name English
METAFOS
Brand Name English
METACID
Brand Name English
O,O-DIMETHYL O-(4-NITROPHENYL) THIOPHOSPHATE
Systematic Name English
METHYL PARATHION [IARC]
Common Name English
METRON
Brand Name English
DIMETHYL PARATHION
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 53501
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
Code System Code Type Description
MESH
D008743
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
MERCK INDEX
M7451
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY Merck Index
PUBCHEM
4130
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
HSDB
1168
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
ECHA (EC/EINECS)
206-050-1
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
FDA UNII
41BCL2O91D
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
EPA CompTox
298-00-0
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
CAS
298-00-0
Created by admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
PRIMARY
Related Record Type Details
METABOLIC ENZYME -> SUBSTRATE
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METABOLIC ENZYME -> SUBSTRATE