Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H10NO5PS |
| Molecular Weight | 263.2089 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COP(=S)(OC)Oc1ccc(cc1)N(=O)=O
InChI
InChIKey=RLBIQVVOMOPOHC-UHFFFAOYSA-N
InChI=1S/C8H10NO5PS/c1-12-15(16,13-2)14-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3
| Molecular Formula | C8H10NO5PS |
| Molecular Weight | 263.2089 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Inhibition of acetylcholinesterase and butyrylcholinesterase by the organophosphorus insecticide methylparathion in the central nervous system of the golden hamster (Mesocricetus auratus). | 1991 |
|
| Prolonged toxicity with intermediate syndrome after combined parathion and methyl parathion poisoning. | 1992 |
|
| Differential toxicities of organophosphate and carbamate insecticides in the nestling European starling (Sturnus vulgaris). | 2000 Aug |
|
| Cholinergic and noncholinergic brain biomarkers of insecticide exposure and effects. | 2000 May |
|
| Analysis of organophosphorus pesticides in honeybee by liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry. | 2001 Aug |
|
| Absorption, distribution, metabolism and excretion of daily oral doses of [14C]methyl parathion in hens. | 2001 Dec 15 |
|
| Solid-phase microextraction method for the determination of atrazine and four organophosphorus pesticides in soil samples by gas chromatography. | 2001 Dec 21 |
|
| Optimizing microwave-assisted solvent extraction (MASE) of pesticides from soil. | 2001 Jan |
|
| Inhibition and recovery of maternal and fetal cholinesterase enzyme activity following a single cutaneous dose of methyl parathion and diazinon, alone and in combination, in pregnant rats. | 2001 Jul-Aug |
|
| The role of glutathione S-transferases in the detoxification of some organophosphorus insecticides in larvae and pupae of the yellow mealworm, Tenebrio molitor (Coleoptera: Tenebrionidae). | 2001 Jun |
|
| Inhibition of cholinesterase enzymes following a single dermal dose of chlorpyrifos and methyl parathion, alone and in combination, in pregnant rats. | 2001 Jun 8 |
|
| Methyl parathion induced alterations in monoaminergic system of developing rat pups. | 2001 Mar |
|
| A modified extraction and clean-up procedure for the detection and determination of parathion-methyl and chlorpyrifos residues in tea. | 2001 May |
|
| Cytochrome P450 2B (CYP2B)-mediated activation of methyl-parathion in rat brain extracts. | 2001 Oct 15 |
|
| Sex-related response to organophosphorus and carbamate insecticides in adult Oriental fruit moth, Grapholita molesta. | 2001 Sep |
|
| Effects of atrazine on acetylcholinesterase activity in midges (Chironomus tentans) exposed to organophosphorus insecticides. | 2001 Sep |
|
| Different quantitation approaches for xenobiotics in human urine samples by liquid chromatography/electrospray tandem mass spectrometry. | 2002 |
|
| Mechanisms of resistance to organophosphates in Tetranychus urticae (Acari: Tetranychidae) from Greece. | 2002 Apr |
|
| Biological monitoring of combined exposure to organophosphates and pyrethroids. | 2002 Aug 5 |
|
| Simple determination of 22 organophosphorous pesticides in human blood using headspace solid-phase microextraction and gas chromatography with mass spectrometric detection. | 2002 Jan |
|
| Increased toxicity to invertebrates associated with a mixture of atrazine and organophosphate insecticides. | 2002 Jul |
|
| Determination of pesticide residues in coconut water by liquid-liquid extraction and gas chromatography with electron-capture plus thermionic specific detection and solid-phase extraction and high-performance liquid chromatography with ultraviolet detection. | 2002 May 31 |
|
| Determination of pesticide residues in nonfatty foods by supercritical fluid extraction and gas chromatography/mass spectrometry: collaborative study. | 2002 Sep-Oct |
|
| Fluorescence polarization immunoassay based on a monoclonal antibody for the detection of the organophosphorus pesticide parathion-methyl. | 2003 Feb 26 |
|
| Fast supercritical fluid extraction and high-resolution gas chromatography with electron-capture and flame photometric detection for multiresidue screening of organochlorine and organophosphorus pesticides in Brazil's medicinal plants. | 2003 Jan 24 |
|
| Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. | 2003 Oct |
|
| Block of neuronal nicotinic acetylcholine receptors by organophosphate insecticides. | 2004 Dec |
|
| What contributes to the combined effect of a complex mixture? | 2004 Dec 1 |
|
| Methyl parathion interaction with human and bovine serum albumin. | 2004 Feb 28 |
|
| Metabolical effects of Folidol 600 on the neotropical freshwater fish matrinxã, Brycon cephalus. | 2004 Jun |
|
| Biotransformation of methyl parathion by glutathione S-transferases. | 2004 Jun |
|
| Effects of methyl parathion (o,o-dimethyl o-4-nitrophenyl phosphorothioate) on rat sperm morphology and sperm count, but not fertility, are associated with decreased ascorbic acid level in the testis. | 2005 Dec 7 |
|
| Short- and long-term response of sunflower to airborne bromoxynil-octanoate under controlled and field conditions. | 2005 Jul |
|
| Evaluation of sublethal biomarkers in Litopenaeus vannamei on foodborne exposure to methyl parathion. | 2005 Sep |
|
| Evaluation of performance of a commercial monoclonal antibody-based fenitrothion immunoassay and application to residual analysis in fruit samples. | 2006 Jan |
|
| Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line. | 2006 Nov 10 |
|
| Sonocatalytic degradation of methyl parathion in the presence of nanometer and ordinary anatase titanium dioxide catalysts and comparison of their sonocatalytic abilities. | 2006 Sep |
|
| Alteration of neurotrophins in the hippocampus and cerebral cortex of young rats exposed to chlorpyrifos and methyl parathion. | 2007 Dec |
|
| Interaction of insecticides with mammalian P-glycoprotein and their effect on its transport function. | 2007 Jul |
|
| Cutinase inhibition by means of insecticidal organophosphates and carbamates. 3. Oxidation of phosphorothionates by chloroperoxidase from Caldariomyces fumago. | 2007 Oct 3 |
|
| Multi-residue determination of pesticides in water using multi-walled carbon nanotubes solid-phase extraction and gas chromatography-mass spectrometry. | 2007 Sep 21 |
|
| Subacute effects of methyl parathion on antioxidant defense systems and lipid peroxidation in rats. | 2008 Aug |
|
| Monitoring of organophosphorus pesticide residues in vegetables of agricultural area in Venezuela. | 2008 Oct |
|
| Organophosphorus pesticides enhance the genotoxicity of benzo(a)pyrene by modulating its metabolism. | 2009 Dec 1 |
|
| Mercaptobenzothiazole-on-gold organic phase biosensor systems: 1. Enhanced organosphosphate pesticide determination. | 2009 Feb |
|
| The effects of selenium on oxidative stress biomarkers in the freshwater characid fish matrinxã, Brycon cephalus (Günther, 1869) exposed to organophosphate insecticide Folisuper 600 BR (methyl parathion). | 2009 Jan |
|
| Methyl-parathion decreases sperm function and fertilization capacity after targeting spermatocytes and maturing spermatozoa. | 2009 Jul 15 |
|
| Organophosphorus pesticide residues in milled rice (Oryza sativa) on the Chinese market and dietary risk assessment. | 2009 Mar |
|
| A transposable class I composite transposon carrying mph (methyl parathion hydrolase) from Pseudomonas sp. strain WBC-3. | 2009 Mar |
|
| Development of square wave voltammetry method for the assessment of organophosphorus compound impact on the cholinesterase of Pheretima with 2,6-dichloroindophenol as a redox indicator. | 2009 Sep |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Jun 26 04:05:05 UTC 2021
by
admin
on
Sat Jun 26 04:05:05 UTC 2021
|
| Record UNII |
41BCL2O91D
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
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| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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EPA PESTICIDE CODE |
53501
Created by
admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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D008743
Created by
admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
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PRIMARY | |||
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M7451
Created by
admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
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PRIMARY | Merck Index | ||
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4130
Created by
admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
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PRIMARY | |||
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1168
Created by
admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
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PRIMARY | |||
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206-050-1
Created by
admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
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PRIMARY | |||
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41BCL2O91D
Created by
admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
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PRIMARY | |||
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298-00-0
Created by
admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
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PRIMARY | |||
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298-00-0
Created by
admin on Sat Jun 26 04:05:05 UTC 2021 , Edited by admin on Sat Jun 26 04:05:05 UTC 2021
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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METABOLIC ENZYME -> SUBSTRATE | |||
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METABOLIC ENZYME -> SUBSTRATE | |||
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METABOLIC ENZYME -> SUBSTRATE |
