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Approval Year

Substance Class
Concept
Record UNII
C0WUS7XXE9
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HM-43239
Code English
HM43239
Code English
5-CHLORO-N-(3-CYCLOPROPYL-5-(((3R,5S)-3,5-DIMETHYLPIPERAZINE-1-YL) METHYL) PHENYL)-4-(6-METHYL-1HINDOL-3-YL) PYRIMIDIN-2-AMINE
Systematic Name English
This is a non-substance concept
Related Record Type Details
TARGET -> INHIBITOR
TARGET -> INHIBITOR
ALSO ACTIVE AGAINST FLT3 ITD and FLT3 D835Y kinases were 1.8 nM and 1.0 nM
IC50
METABOLIC ENZYME -> SUBSTRATE
METABOLIC ENZYME -> INHIBITOR
METABOLIC ENZYME -> INHIBITOR
TARGET -> INHIBITOR
SALT/SOLVATE -> PARENT
OFF-TARGET->INHIBITOR
TARGET -> INHIBITOR
ALSO ACTIVE AGAINST FLT3 ITD and FLT3 D835Y kinases were 1.8 nM and 1.0 nM
METABOLIC ENZYME -> SUBSTRATE
TARGET -> INHIBITOR
TARGET -> INHIBITOR
METABOLIC ENZYME -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
This is a non-substance concept