Approval Year
Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 12:34:33 GMT 2023
by
admin
on
Sat Dec 16 12:34:33 GMT 2023
|
Protein Type | RECEPTOR |
Protein Sub Type | TYROSINE KINASE |
Sequence Origin | HUMAN |
Sequence Type | COMPLETE |
Record UNII |
4796L35A70
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
P36888
Created by
admin on Sat Dec 16 12:34:34 GMT 2023 , Edited by admin on Sat Dec 16 12:34:34 GMT 2023
|
PRIMARY | |||
|
4796L35A70
Created by
admin on Sat Dec 16 12:34:34 GMT 2023 , Edited by admin on Sat Dec 16 12:34:34 GMT 2023
|
PRIMARY | |||
|
P36888
Created by
admin on Sat Dec 16 12:34:34 GMT 2023 , Edited by admin on Sat Dec 16 12:34:34 GMT 2023
|
PRIMARY |
From | To |
---|---|
1_9 | 1_39 |
1_77 | 1_88 |
1_173 | 1_180 |
1_206 | 1_215 |
1_246 | 1_304 |
1_342 | 1_381 |
1_355 | 1_366 |
Glycosylation Type | HUMAN |
Glycosylation Link Type | Site |
---|---|
N | 1_17 |
N | 1_74 |
N | 1_125 |
N | 1_280 |
N | 1_297 |
N | 1_325 |
N | 1_328 |
N | 1_447 |
N | 1_476 |
N | 1_515 |
Related Record | Type | Details | ||
---|---|---|---|---|
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR->OFF-TARGET |
|
||
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
IC50
|
||
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
IC50
|
||
|
INHIBITOR -> TARGET |
IC50
|
||
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
ALSO ACTIVE AGAINST FLT3 ITD and FLT3 D835Y kinases were 1.8 nM and 1.0 nM
|
||
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
IC50
|
||
|
INHIBITOR -> TARGET |
Kd
|
||
|
INHIBITOR -> TARGET |
IC50
|
||
|
LIGAND->TARGET |
|
||
|
INHIBITOR -> TARGET |
IC50
|
||
|
INHIBITOR -> TARGET |
IC50
|
||
|
INHIBITOR -> TARGET |
IC50
|
||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET |
ALSO ACTIVE AGAINST FLT3-ITD mutants
IC50
|
||
|
INHIBITOR -> TARGET |
|
||
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
PRECLINICAL
|
||
|
INHIBITOR -> TARGET |
COMPETITIVE INHIBITOR
IC50
|
||
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET | |||
|
INHIBITOR -> TARGET |
IC50
|
||
|
INHIBITOR -> TARGET |
IC50
|
Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
---|---|---|---|---|---|---|
MOL_WEIGHT | CHEMICAL |
|
||||
Molecular Formula | CHEMICAL |
|