U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:13:01 GMT 2023
Edited
by admin
on Sat Dec 16 14:13:01 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type BISPECIFIC T CELL ENGAGER
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
P9I9Z3MF7Z
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Emirodatamab
INN   USAN  
Official Name English
AMG 427
Code English
EXTENDED HALF-LIFE ANTI-FLT3 X ANTI-CD3 BITE (BISPECIFIC T CELL ENGAGER) ANTIBODY CONSTRUCT
Common Name English
AMG-427
Code English
ANTI-FLT3/CD3 BITE ANTIBODY AMG 427
Common Name English
emirodatamab [INN]
Common Name English
EMIRODATAMAB [USAN]
Common Name English
Immunoglobulin, bispecific, anti-(human fms-like tyrosine kinase FLT3) (human monoclonal FLT3_bispecific_1 single-chain variable fragment VH1-(GGGGS)3-VL1) fusion protein with peptide linker (GGGGS) fusion protein with immunoglobulin anti-(human CD3 anti
Common Name English
Immunoglobulin scFv-scFv-scFc, anti-[Homo sapiens FLT3 (fms related receptor tyrosine kinase 3, STK1, FLK2, CD135)] and anti-[Homo sapiens CD3E (CD3e, CD3 epsilon)], single chain monoclonal antibody, bispecific; scFv-scFv-scFc fused single chain (1-989)
Common Name English
Code System Code Type Description
CAS
2449199-61-3
Created by admin on Sat Dec 16 14:13:01 GMT 2023 , Edited by admin on Sat Dec 16 14:13:01 GMT 2023
PRIMARY
INN
12028
Created by admin on Sat Dec 16 14:13:01 GMT 2023 , Edited by admin on Sat Dec 16 14:13:01 GMT 2023
PRIMARY
FDA UNII
P9I9Z3MF7Z
Created by admin on Sat Dec 16 14:13:01 GMT 2023 , Edited by admin on Sat Dec 16 14:13:01 GMT 2023
PRIMARY
USAN
LM-112
Created by admin on Sat Dec 16 14:13:01 GMT 2023 , Edited by admin on Sat Dec 16 14:13:01 GMT 2023
PRIMARY
NCI_THESAURUS
C156399
Created by admin on Sat Dec 16 14:13:01 GMT 2023 , Edited by admin on Sat Dec 16 14:13:01 GMT 2023
PRIMARY NCIT
From To
1_22 1_97
1_46 1_239
1_162 1_227
1_274 1_350
1_414 1_482
1_511 1_768
1_514 1_771
1_546 1_587
1_577 1_606
1_652 1_710
1_803 1_844
1_834 1_863
1_909 1_967
Related Record Type Details
TARGET->LIGAND
TARGET -> ACTIVATOR
TARGET->LIGAND
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL