Details
Stereochemistry | ACHIRAL |
Molecular Formula | C25H17F4N5O2 |
Molecular Weight | 495.4293 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cc1cnc(-c2ccc(-c3ccc(cc3F)N=C(Nc4c(cc(cc4F)F)F)O)c5CN=C(c25)O)[nH]1
InChI
InChIKey=MWHHJYUHCZWSLS-UHFFFAOYSA-N
InChI=1S/C25H17F4N5O2/c1-11-9-30-23(32-11)16-5-4-14(17-10-31-24(35)21(16)17)15-3-2-13(8-18(15)27)33-25(36)34-22-19(28)6-12(26)7-20(22)29/h2-9H,10H2,1H3,(H,30,32)(H,31,35)(H2,33,34,36)
Molecular Formula | C25H17F4N5O2 |
Molecular Weight | 495.4293 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Jun 26 07:47:16 UTC 2021
by
admin
on
Sat Jun 26 07:47:16 UTC 2021
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Record UNII |
TQ6PBX1JU0
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Record Status |
Validated (UNII)
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Record Version |
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-
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11799
Created by
admin on Sat Jun 26 07:47:17 UTC 2021 , Edited by admin on Sat Jun 26 07:47:17 UTC 2021
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TQ6PBX1JU0
Created by
admin on Sat Jun 26 07:47:17 UTC 2021 , Edited by admin on Sat Jun 26 07:47:17 UTC 2021
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118480924
Created by
admin on Sat Jun 26 07:47:17 UTC 2021 , Edited by admin on Sat Jun 26 07:47:17 UTC 2021
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OFF-TARGET->INHIBITOR |
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TARGET -> INHIBITOR |
ALSO ACTIVE AGAINST FLT3-ITD mutants
IC50
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ACTIVE MOIETY |