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Details

Stereochemistry RACEMIC
Molecular Formula C12H17O4PS2
Molecular Weight 320.3674
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHENTHOATE

SMILES

CCOC(=O)C(c1ccccc1)SP(=S)(OC)OC

InChI

InChIKey=XAMUDJHXFNRLCY-UHFFFAOYSA-N
InChI=1S/C12H17O4PS2/c1-4-16-12(13)11(10-8-6-5-7-9-10)19-17(18,14-2)15-3/h5-9,11H,4H2,1-3H3

HIDE SMILES / InChI

Molecular Formula C12H17O4PS2
Molecular Weight 320.3674
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Approval Year

PubMed

PubMed

TitleDatePubMed
Stereo- and enantioselective determination of pesticides in soil by using achiral and chiral liquid chromatography in combination with matrix solid-phase dispersion.
2003 May-Jun
Cardiac responses of Pacific oyster Crassostrea gigas to agents modulating cholinergic function.
2004 Dec
Rapid report acetamiprid resistance and cross-resistance in the diamondback moth, Plutella xylostella.
2004 Sep
Toxicity of insecticides to the sweetpotato whitefly (Hemiptera: Aleyrodidae) and its natural enemies.
2007 Jul
Multi-residue determination of pesticides in water using multi-walled carbon nanotubes solid-phase extraction and gas chromatography-mass spectrometry.
2007 Sep 21
Solid-phase microextraction-liquid chromatography-mass spectrometry applied to the analysis of insecticides in honey.
2008 Jan
An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes.
2009 Aug
A phase II clinical trial to assess the safety of clonidine in acute organophosphorus pesticide poisoning.
2009 Aug 20
Pralidoxime in acute organophosphorus insecticide poisoning--a randomised controlled trial.
2009 Jun 30
Characterization of human cytochrome P450 induction by pesticides.
2012 Mar 29
The inhibition of major human hepatic cytochrome P450 enzymes by 18 pesticides: comparison of the N-in-one and single substrate approaches.
2013 Aug
Patents
Substance Class Chemical
Created
by admin
on Sat Jun 26 00:22:37 UTC 2021
Edited
by admin
on Sat Jun 26 00:22:37 UTC 2021
Record UNII
J96Q7F091K
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PHENTHOATE
HSDB   ISO  
Common Name English
PHENTHOATE (PAP) FENTHOATE
Common Name English
BAYER-18,510
Code English
TAGSON
Brand Name English
PHENDAL
Common Name English
BAYER-18510
Code English
ACETIC ACID, MERCAPTOPHENYL-, ETHYL ESTER O,O-DIMETHYL PHOSPHORODITHIOATE
Common Name English
O,O-DIMETHYL S-.ALPHA.-ETHOXYCARBONYLBENZYL PHOSPHORODITHIOATE
Common Name English
DIMEPHENTHOATE
Common Name English
PAPTHION
Common Name English
ETHYL ((DIMETHOXYPHOSPHOROTHIOYL)SULFANYL)(PHENYL)ACETATE
Systematic Name English
S-.ALPHA.-ETHOXYCARBONYLBENZYL DIMETHYL PHOSPHOROTHIOLOTHIONATE
Common Name English
S-(.ALPHA.-(ETHOXYCARBONYL)BENZYL) O,O-DIMETHYL PHOSPHORODITHIOATE
Systematic Name English
PHENTHOATE [HSDB]
Common Name English
BENZENEACETIC ACID, .ALPHA.-((DIMETHOXYPHOSPHINOTHIOYL)THIO)-, ETHYL ESTER
Common Name English
BAY-33051
Code English
(+/-)-PHENTHOATE
Common Name English
PAP
Common Name English
TSIDIAL
Brand Name English
ACETIC ACID, MERCAPTOPHENYL-, ETHYL ESTER, S-ESTER WITH O,O-DIMETHYL PHOSPHORODITHIOATE
Common Name English
ETHYL .ALPHA.-((DIMETHOXYPHOSPHINOTHIOYL)THIO)BENZENEACETATE
Systematic Name English
ETHYL A-((DIMETHOXYPHOSPHINOTHIOYL)THIO)BENZENEACETATE
Common Name English
PHENTHOATE [ISO]
Common Name English
PHOSPHORODITHIOIC ACID, O,O-DIMETHYL ESTER, S-ESTER WITH ETHYL MERCAPTOPHENYLACETATE
Common Name English
PHENTHOATE, (+/-)-
Common Name English
Code System Code Type Description
MESH
C008838
Created by admin on Sat Jun 26 00:22:37 UTC 2021 , Edited by admin on Sat Jun 26 00:22:37 UTC 2021
PRIMARY
ECHA (EC/EINECS)
219-997-0
Created by admin on Sat Jun 26 00:22:37 UTC 2021 , Edited by admin on Sat Jun 26 00:22:37 UTC 2021
PRIMARY
HSDB
1708
Created by admin on Sat Jun 26 00:22:37 UTC 2021 , Edited by admin on Sat Jun 26 00:22:37 UTC 2021
PRIMARY
EPA CompTox
2597-03-7
Created by admin on Sat Jun 26 00:22:37 UTC 2021 , Edited by admin on Sat Jun 26 00:22:37 UTC 2021
PRIMARY
PUBCHEM
17435
Created by admin on Sat Jun 26 00:22:37 UTC 2021 , Edited by admin on Sat Jun 26 00:22:37 UTC 2021
PRIMARY
FDA UNII
J96Q7F091K
Created by admin on Sat Jun 26 00:22:37 UTC 2021 , Edited by admin on Sat Jun 26 00:22:37 UTC 2021
PRIMARY
WIKIPEDIA
PHENTHOATE
Created by admin on Sat Jun 26 00:22:37 UTC 2021 , Edited by admin on Sat Jun 26 00:22:37 UTC 2021
PRIMARY
CAS
2597-03-7
Created by admin on Sat Jun 26 00:22:37 UTC 2021 , Edited by admin on Sat Jun 26 00:22:37 UTC 2021
PRIMARY
Related Record Type Details
METABOLIC ENZYME -> INHIBITOR
CYP2C9 activity was extensively inhibited (more than 90% inhibition) by organophosphorus insecticides phenthoate
METABOLIC ENZYME -> INHIBITOR
Extensive inhibitions of CYP2A6-associated activity (94–98%) were observed with phenthoate
METABOLIC ENZYME -> INHIBITOR
Phenthoate inhibited CYP1A1/2 activities more than 90%.
METABOLIC ENZYME -> INHIBITOR
Screening of potential CYP2B6 inhibitions illustrates that CYP2B6 activity was extensively inhibited by all tested organophosphate pesticides. Phenthoate resulted in 91% inhibition.
METABOLIC ENZYME -> INHIBITOR
Phenthoate inhibited CYP1A1/2 activities more than 90%.
METABOLIC ENZYME -> INHIBITOR
Human hepatic CYP2C8 activities after incubation with different pesticides showed that CYP2C8 activities were inhibited extensively by phenthoate (100,90%).