PROFENOFOS

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H15BrClO3PS
Molecular Weight	373.631
Optical Activity	( + / - )
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PROFENOFOS

Structure Search

SMILES

CCCSP(=O)(OCC)OC1=CC=C(Br)C=C1Cl

InChI

InChIKey=QYMMJNLHFKGANY-UHFFFAOYSA-N

InChI=1S/C11H15BrClO3PS/c1-3-7-18-17(14,15-4-2)16-11-6-5-9(12)8-10(11)13/h5-6,8H,3-4,7H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C11H15BrClO3PS
Molecular Weight	373.631
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:19:40 GMT 2023` Edited by `admin` on `Fri Dec 15 17:19:40 GMT 2023`
Record UNII	7J04O7BS4W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PROFENOFOS

Common Name

English

PROFENOFOS [HSDB]

Common Name

English

CGA-15324

Code

English

PROFENOFOS [MI]

Common Name

English

CURACRON

Brand Name

English

SELECRON

Brand Name

English

PROFENOFOS [ISO]

Common Name

English

(RS)-(O-4-BROMO-2-CHLOROPHENYL O-ETHYL S-PROPYL PHOSPHOROTHIOATE)

Common Name

English

OMS-2004

Code

English

O-(4-BROMO-2-CHLOROPHENYL) O-ETHYL S-PROPYL PHOSPHOROTHIOATE

Systematic Name

English

PROFENOPHOS

Brand Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

111401

Created by admin on Fri Dec 15 17:19:40 GMT 2023 , Edited by admin on Fri Dec 15 17:19:40 GMT 2023

Code System Code Type Description

HSDB

6992

Created by admin on Fri Dec 15 17:19:40 GMT 2023 , Edited by admin on Fri Dec 15 17:19:40 GMT 2023

PRIMARY

ALANWOOD

profenofos

Created by admin on Fri Dec 15 17:19:40 GMT 2023 , Edited by admin on Fri Dec 15 17:19:40 GMT 2023

PRIMARY

FDA UNII

7J04O7BS4W

Created by admin on Fri Dec 15 17:19:40 GMT 2023 , Edited by admin on Fri Dec 15 17:19:40 GMT 2023

PRIMARY

PUBCHEM

38779

Created by admin on Fri Dec 15 17:19:40 GMT 2023 , Edited by admin on Fri Dec 15 17:19:40 GMT 2023

PRIMARY

ECHA (EC/EINECS)

255-255-2

Created by admin on Fri Dec 15 17:19:40 GMT 2023 , Edited by admin on Fri Dec 15 17:19:40 GMT 2023

PRIMARY

CHEBI

38845

Created by admin on Fri Dec 15 17:19:40 GMT 2023 , Edited by admin on Fri Dec 15 17:19:40 GMT 2023

PRIMARY

MESH

C024273

Created by admin on Fri Dec 15 17:19:40 GMT 2023 , Edited by admin on Fri Dec 15 17:19:40 GMT 2023

PRIMARY

EPA CompTox

DTXSID3032464

Created by admin on Fri Dec 15 17:19:40 GMT 2023 , Edited by admin on Fri Dec 15 17:19:40 GMT 2023

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WIKIPEDIA

Profenofos

Created by admin on Fri Dec 15 17:19:40 GMT 2023 , Edited by admin on Fri Dec 15 17:19:40 GMT 2023

PRIMARY

MERCK INDEX

m9156

Created by admin on Fri Dec 15 17:19:40 GMT 2023 , Edited by admin on Fri Dec 15 17:19:40 GMT 2023

PRIMARY

Merck Index

CAS

41198-08-7

Created by admin on Fri Dec 15 17:19:40 GMT 2023 , Edited by admin on Fri Dec 15 17:19:40 GMT 2023

PRIMARY

Related Record Type Details


					L0423Z5LDW

CYTOCHROME P450 2C8

METABOLIC ENZYME -> INHIBITOR

Comments:

inhibitions between 59 and 84% were observed with profenofos

Amount:


					L9DP834D1P

CYTOCHROME P450 2C9

METABOLIC ENZYME -> INHIBITOR

Comments:

CYP2C9 activity was extensively inhibited (more than 90% inhibition) by organophosphorus insecticides profenofos

Amount:


					0UY97CSG1T

CYTOCHROME P450 2B6

INNOVATOR->PARENT

Comments:

Screening of potential CYP2B6 inhibitions illustrates that CYP2B6 activity was extensively inhibited by all tested organophosphate pesticides. Inhibition percentages were 100% with profenofos.


					VK4SQL11C0

CYTOCHROME P450 1A2

METABOLIC ENZYME -> INHIBITOR

Comments:

Profenofos inhibited CYP1A1/2 activities more than 90%.


					9DX651UO0D

CYTOCHROME P450 1A1

METABOLIC ENZYME -> INHIBITOR

Comments:

Profenofos inhibited CYP1A1/2 activities more than 90%.

Amount: