PF-06650833

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H20FN3O4
Molecular Weight	361.3675
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC[C@H]1[C@@H](COC2=C3C=C(OC)C(=CC3=CC=N2)C(N)=O)NC(=O)[C@H]1F

InChI

InChIKey=JKDGKIBAOAFRPJ-ZBINZKHDSA-N

InChI=1S/C18H20FN3O4/c1-3-10-13(22-17(24)15(10)19)8-26-18-11-7-14(25-2)12(16(20)23)6-9(11)4-5-21-18/h4-7,10,13,15H,3,8H2,1-2H3,(H2,20,23)(H,22,24)/t10-,13+,15-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C18H20FN3O4
Molecular Weight	361.3675
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Interleukin-1 receptor-associated kinase 4 2	Inhibitor 7468		0.2 nM [IC50]

Substance Class	Chemical Created by `admin` on `Tue Oct 22 07:57:46 UTC 2019` Edited by `admin` on `Tue Oct 22 07:57:46 UTC 2019`
Record UNII	S3F315JJXI
Record Status	`Validated (UNII)`
Record Version