Details
Stereochemistry | ACHIRAL |
Molecular Formula | Fe |
Molecular Weight | 55.845 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 3 |
SHOW SMILES / InChI
SMILES
[Fe+3]
InChI
InChIKey=VTLYFUHAOXGGBS-UHFFFAOYSA-N
InChI=1S/Fe/q+3
Molecular Formula | Fe |
Molecular Weight | 55.845 |
Charge | 3 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
DescriptionSources: https://cameochemicals.noaa.gov/chemical/3468 | https://www.ncbi.nlm.nih.gov/pubmed/2135524https://books.google.ru/books?id=vxtxWneRBN4C&pg=PA1103v=onepage&q&f=falsehttps://mistralhowto.wordpress.com/2012/03/12/what-is-pigment-yellow-42-and-what-is-it-used-for/ | http://sensientfoodcolors.com/en-us/confection/iron-oxides-approved-by-the-fda/ | https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=73.2250 | https://www.drugs.com/inactive/ferric-oxide-yellow-381.htmlhttp://www.mfc.co.jp/english/eng/product/sanferol/pdf/fls_gras_notice.pdfhttps://www.accessdata.fda.gov/drugsatfda_docs/nda/2014/205874Orig1s000PharmR.pdfhttp://www.edta-chelate.com/ferric-ammonium-edta-liquid--1640836.htmlCurator's Comment: description was created based on several sources, including
http://www.mfc.co.jp/english/eng/product/sanferol/index.html
Sources: https://cameochemicals.noaa.gov/chemical/3468 | https://www.ncbi.nlm.nih.gov/pubmed/2135524https://books.google.ru/books?id=vxtxWneRBN4C&pg=PA1103v=onepage&q&f=falsehttps://mistralhowto.wordpress.com/2012/03/12/what-is-pigment-yellow-42-and-what-is-it-used-for/ | http://sensientfoodcolors.com/en-us/confection/iron-oxides-approved-by-the-fda/ | https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=73.2250 | https://www.drugs.com/inactive/ferric-oxide-yellow-381.htmlhttp://www.mfc.co.jp/english/eng/product/sanferol/pdf/fls_gras_notice.pdfhttps://www.accessdata.fda.gov/drugsatfda_docs/nda/2014/205874Orig1s000PharmR.pdfhttp://www.edta-chelate.com/ferric-ammonium-edta-liquid--1640836.html
Curator's Comment: description was created based on several sources, including
http://www.mfc.co.jp/english/eng/product/sanferol/index.html
Ferric Ammonium EDTA Solution is normally used as a photographic chemical for a bleaching agent in the process of colour washing. It is also used as a complexing, and oxidizing agent & as a fertilizer and catalyst. EDTA acid are colourless, water-soluble solid that are widely used to dissolve scale. The usefulness of these ammonium salts arise because of its role as a chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: GO:0006927 Sources: https://www.ncbi.nlm.nih.gov/pubmed/21121365 |
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Target ID: CHEMBL2364184 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Primary | Unknown Approved UseUnknown |
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Primary | SANFEROL Approved UseIt has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency. |
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Inactive ingredient | Oxycontin Approved UseOxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics. Launch Date1998 |
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Palliative | AURYXIA Approved UseFerric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis. Launch Date2014 |
PubMed
Title | Date | PubMed |
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[Effects of ferric fluoride compounds on dental enamel]. | 1954 Nov 15 |
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The formation of ferritin from apoferritin. Kinetics and mechanism of iron uptake. | 1972 Jan |
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The formation of ferritin from apoferritin. Catalytic action of apoferritin. | 1973 Oct |
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The absorption of iron as supplements in infant cereal and infant formulas. | 1975 May |
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Biological availability of iron supplements for rats, chicks and humans. | 1976 Feb |
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Contact dermatitis to yellow iron oxide. | 1985 Aug |
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Carcinogenicity studies on natural and man-made fibres with the intraperitoneal test in rats. | 1989 |
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Effect of physical exercise and vitamin C on absorption of ferric sodium citrate. | 1996 Dec |
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New phosphate binding agents: ferric compounds. | 1999 Jun |
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Non-invasive and non-destructive micro-XRF and micro-Raman analysis of a decorative wallpaper from the beginning of the 19th century. | 2007 Feb |
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Interaction of omapatrilat with FD&C Blue No. 2 lake during dissolution of modified release tablets. | 2007 Jul 18 |
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Fabrication of FeF3 Nanoflowers on CNT branches and their application to high power lithium rechargeable batteries. | 2010 Dec 7 |
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Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions. | 2011 Jun |
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Finnish wallpaper pigments in the 18th-19th century: presence of KFe3(CrO4)2(OH)6 and odd pigment mixtures. | 2013 Apr |
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Microwave assisted convenient one-pot synthesis of coumarin derivatives via Pechmann condensation catalyzed by FeF3 under solvent-free conditions and antimicrobial activities of the products. | 2014 Aug 26 |
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FeF(3) catalyzed cascade C-C and C-N bond formation: synthesis of differentially substituted triheterocyclic benzothiazole functionalities under solvent-free condition. | 2014 May |
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Heme Binding by Corynebacterium diphtheriae HmuT: Function and Heme Environment. | 2015 Nov 3 |
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Superior electrochemical performance of N-doped nanocrystalline FeF(3)/C with a single-step solid-state process. | 2016 Oct 4 |
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Phosphorus recovery from biogas slurry by ultrasound/H(2)O(2) digestion coupled with HFO/biochar adsorption process. | 2017 Feb |
Sample Use Guides
In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
Unknown
Route of Administration:
Unknown
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/286710
Bovine enamel was treated with 10 mM FeF3 (Ferric fluoride)
Substance Class |
Chemical
Created
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Record UNII |
91O4LML611
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PRIMARY | RxNorm |
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Deferasirox is an orally active chelator that is selective for iron (as Fe3+). It is a tridentate ligand that binds iron with high affinity in a 2:1 ratio.
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Converts Ferric ion to Ferrous Ion in Methemoglobin
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ACTIVE MOIETY |