U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 3Cl.Fe
Molecular Weight 162.204
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Ferric Chloride

SMILES

[Cl-].[Cl-].[Cl-].[Fe+3]

InChI

InChIKey=RBTARNINKXHZNM-UHFFFAOYSA-K
InChI=1S/3ClH.Fe/h3*1H;/q;;;+3/p-3

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Ferric Ammonium EDTA Solution is normally used as a photographic chemical for a bleaching agent in the process of colour washing. It is also used as a complexing, and oxidizing agent & as a fertilizer and catalyst. EDTA acid are colourless, water-soluble solid that are widely used to dissolve scale. The usefulness of these ammonium salts arise because of its role as a chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+.

Originator

Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

1998
Palliative
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

2014
PubMed

PubMed

TitleDatePubMed
Phosphorus recovery from biogas slurry by ultrasound/H2O2 digestion coupled with HFO/biochar adsorption process.
2017-02
Superior electrochemical performance of N-doped nanocrystalline FeF3/C with a single-step solid-state process.
2016-10-04
Heme Binding by Corynebacterium diphtheriae HmuT: Function and Heme Environment.
2015-11-03
Microwave assisted convenient one-pot synthesis of coumarin derivatives via Pechmann condensation catalyzed by FeF3 under solvent-free conditions and antimicrobial activities of the products.
2014-08-26
FeF(3) catalyzed cascade C-C and C-N bond formation: synthesis of differentially substituted triheterocyclic benzothiazole functionalities under solvent-free condition.
2014-05
Finnish wallpaper pigments in the 18th-19th century: presence of KFe3(CrO4)2(OH)6 and odd pigment mixtures.
2013-04
Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions.
2011-06
Fabrication of FeF3 Nanoflowers on CNT branches and their application to high power lithium rechargeable batteries.
2010-12-07
Interaction of omapatrilat with FD&C Blue No. 2 lake during dissolution of modified release tablets.
2007-07-18
Non-invasive and non-destructive micro-XRF and micro-Raman analysis of a decorative wallpaper from the beginning of the 19th century.
2007-02
New phosphate binding agents: ferric compounds.
1999-06
Effect of physical exercise and vitamin C on absorption of ferric sodium citrate.
1996-12
Carcinogenicity studies on natural and man-made fibres with the intraperitoneal test in rats.
1989
Contact dermatitis to yellow iron oxide.
1985-08
Biological availability of iron supplements for rats, chicks and humans.
1976-02
The absorption of iron as supplements in infant cereal and infant formulas.
1975-05
The formation of ferritin from apoferritin. Catalytic action of apoferritin.
1973-10
The formation of ferritin from apoferritin. Kinetics and mechanism of iron uptake.
1972-01
[Effects of ferric fluoride compounds on dental enamel].
1954-11-15
Patents

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Bovine enamel was treated with 10 mM FeF3 (Ferric fluoride)
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:09:24 GMT 2025
Edited
by admin
on Mon Mar 31 18:09:24 GMT 2025
Record UNII
U38V3ZVV3V
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IRON(III) CHLORIDE
HSDB  
Preferred Name English
Ferric Chloride
II   INCI   MI   VANDF   WHO-DD  
INCI  
Official Name English
Ferric chloride [WHO-DD]
Common Name English
FERRIC CHLORIDE [MI]
Common Name English
NSC-135798
Code English
FERRIC CHLORIDE ANHYDROUS
Common Name English
FERRIC CHLORIDE, ANHYDROUS
Common Name English
IRON PERCHLORIDE
Common Name English
IRON TRICHLORIDE
Systematic Name English
FLORES MARTIS
Common Name English
NSC-51150
Code English
IRON(III) CHLORIDE [HSDB]
Common Name English
IRON CHLORIDE (FECL3)
Common Name English
FERRIC CHLORIDE [VANDF]
Common Name English
FERRIC CHLORIDE [II]
Common Name English
Classification Tree Code System Code
CFR 21 CFR 176.170
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
CFR 21 CFR 184.1297
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
EPA PESTICIDE CODE 34901
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
Code System Code Type Description
EVMPD
SUB13836MIG
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
CHEBI
30808
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
MESH
C024555
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
WIKIPEDIA
IRON(III) CHLORIDE
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
CONCEPT Industrial Aid
MERCK INDEX
m5316
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY Merck Index
CAS
7705-08-0
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
NSC
135798
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
DAILYMED
U38V3ZVV3V
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
SMS_ID
100000078720
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
NSC
51150
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
RXCUI
24898
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY RxNorm
DRUG BANK
DB15536
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
EPA CompTox
DTXSID8020622
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
PUBCHEM
24380
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
ECHA (EC/EINECS)
231-729-4
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
HSDB
449
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
NCI_THESAURUS
C76753
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
FDA UNII
U38V3ZVV3V
Created by admin on Mon Mar 31 18:09:24 GMT 2025 , Edited by admin on Mon Mar 31 18:09:24 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
SOLVATE->ANHYDROUS
SOLVATE->ANHYDROUS
Related Record Type Details
ACTIVE MOIETY