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Details

Stereochemistry ACHIRAL
Molecular Formula C10H12N2O8.Fe.Na
Molecular Weight 367.046
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM FEREDETATE

SMILES

[Na+].[Fe+3].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O

InChI

InChIKey=MKWYFZFMAMBPQK-UHFFFAOYSA-J
InChI=1S/C10H16N2O8.Fe.Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;+3;+1/p-4

HIDE SMILES / InChI
Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C10H12N2O8
Molecular Weight 288.2109
Charge -4
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Sources: https://books.google.ru/books?id=vxtxWneRBN4C&pg=PA1103&#v=onepage&q&f=falsehttps://mistralhowto.wordpress.com/2012/03/12/what-is-pigment-yellow-42-and-what-is-it-used-for/ | http://sensientfoodcolors.com/en-us/confection/iron-oxides-approved-by-the-fda/ | https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=73.2250 | https://www.drugs.com/inactive/ferric-oxide-yellow-381.htmlhttp://www.mfc.co.jp/english/eng/product/sanferol/pdf/fls_gras_notice.pdfhttps://www.accessdata.fda.gov/drugsatfda_docs/nda/2014/205874Orig1s000PharmR.pdfhttps://cameochemicals.noaa.gov/chemical/3468 | https://www.ncbi.nlm.nih.gov/pubmed/2135524http://www.edta-chelate.com/ferric-ammonium-edta-liquid--1640836.htmlhttps://books.google.ru/books?id=3hLmyma2-MsC&pg=PA241&lpg=PA241&dq=FERRIC+AMMONIUM+CHLORIDE retrieved from A Consumer's Dictionary of Cosmetic Ingredients, 7th Edition: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics and Cosmeceuticals By Ruth Winterhttps://www.ncbi.nlm.nih.gov/pubmed/27995746 | http://onlinelibrary.wiley.com/doi/10.1002/047084289X.rn01568/abstract?userIsAuthenticated=false&deniedAccessCustomisedMessage=
Curator's Comment: description was created based on several sources, including http://www.mfc.co.jp/english/eng/product/sanferol/index.html

Ferric bromide, red-brown odorless compound, an oxidizing reagent, used as a catalyst for organic reactions, particularly in bromination of aromatic compounds.

Originator

Monsanto Chemicals
43
Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

1921
1447
Targets

Targets

Primary TargetPharmacologyConditionPotency
Activator
1404
Chelating Agent
143
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Basic research
Unknown

Approved Use

Unknown
Primary
Approved
8307
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Approved
8307
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

9.0935997E11
Curative
Approved
8307
RADIOGARDASE

Approved Use

Insoluble Prussian blue is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination.

Launch Date

1.06496642E12
Palliative
Approved
8307
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

1.40978881E12
PubMed

PubMed

TitleDatePubMed
[Effects of ferric fluoride compounds on dental enamel].
1954 Nov 15
The formation of ferritin from apoferritin. Kinetics and mechanism of iron uptake.
1972 Jan
The formation of ferritin from apoferritin. Catalytic action of apoferritin.
1973 Oct
The absorption of iron as supplements in infant cereal and infant formulas.
1975 May
Biological availability of iron supplements for rats, chicks and humans.
1976 Feb
Contact dermatitis to yellow iron oxide.
1985 Aug
Carcinogenicity studies on natural and man-made fibres with the intraperitoneal test in rats.
1989
Effect of physical exercise and vitamin C on absorption of ferric sodium citrate.
1996 Dec
New phosphate binding agents: ferric compounds.
1999 Jun
Non-invasive and non-destructive micro-XRF and micro-Raman analysis of a decorative wallpaper from the beginning of the 19th century.
2007 Feb
Interaction of omapatrilat with FD&C Blue No. 2 lake during dissolution of modified release tablets.
2007 Jul 18
Metal-mediated cyclization of aryl and benzyl glycidyl ethers: a complete scenario.
2008 Dec 17
Fabrication of FeF3 Nanoflowers on CNT branches and their application to high power lithium rechargeable batteries.
2010 Dec 7
Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions.
2011 Jun
Oxidative aromatic C-N bond formation: convenient synthesis of N-amino-3-nitrile-indoles via FeBr3-mediated intramolecular cyclization.
2011 May 21
Finnish wallpaper pigments in the 18th-19th century: presence of KFe3(CrO4)2(OH)6 and odd pigment mixtures.
2013 Apr
Microwave assisted convenient one-pot synthesis of coumarin derivatives via Pechmann condensation catalyzed by FeF3 under solvent-free conditions and antimicrobial activities of the products.
2014 Aug 26
FeF(3) catalyzed cascade C-C and C-N bond formation: synthesis of differentially substituted triheterocyclic benzothiazole functionalities under solvent-free condition.
2014 May
Heme Binding by Corynebacterium diphtheriae HmuT: Function and Heme Environment.
2015 Nov 3
Nazarov cyclization of 1,4-pentadien-3-ols: preparation of cyclopenta[b]indoles and spiro[indene-1,4'-quinoline]s.
2016 Feb 14
Mechanisms and origins of the switchable regioselectivity of FeBr3-catalyzed [1,2]-aryl and [1,2]-alkyl shifts of α-aryl aldehydes.
2016 Feb 28
Halide Influence on Molecular and Supramolecular Arrangements of Iron Complexes with a 3,5-Bis(2-Pyridyl)-1,2,4,6-Thiatriazine Ligand.
2016 Jun 6
Iron-Catalyzed Regioselective Transfer Hydrogenative Couplings of Unactivated Aldehydes with Simple Alkenes.
2016 May 17
Superior electrochemical performance of N-doped nanocrystalline FeF(3)/C with a single-step solid-state process.
2016 Oct 4
Phosphorus recovery from biogas slurry by ultrasound/H(2)O(2) digestion coupled with HFO/biochar adsorption process.
2017 Feb
A Simplified Fe-Based PhotoATRP Using Only Monomers and Solvent.
2017 Jul
Patents

Patents

20080188032
43
20090216060
43
6258758
43
US 5206265 A
43
US2385188
43
US4364871
43
US6881255
43
US6903235
43
US7198668
43

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
As a food supplement, ferric sodium pyrophosphate is administered orally.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sun Dec 18 21:20:41 UTC 2022
Edited
by admin
on Sun Dec 18 21:20:41 UTC 2022
Record UNII
403J23EMFA
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM FEREDETATE
INN   MART.   WHO-DD  
INN  
Official Name English
FERROSTRANE
Brand Name English
SYTRON
Brand Name English
EDETIC ACID SODIUM IRON SALT
Common Name English
SODIUM FEREDETATE [MART.]
Common Name English
IRON(3+) SODIUM 2,2',2'',2'''-(ETHANE-1,2-DIYLDINITRILO)TETRAACETATE (1:1:1)
Systematic Name English
SODIUM IRON EDETATE
Systematic Name English
EDTA FERRIC SODIUM SALT
Common Name English
SODIUM IRON ETHYLENEDIAMINE TETRAACETIC ACID
Systematic Name English
IRON(III) SODIUM ETHYLENEDIAMINETETRAACETATE
Systematic Name English
IRON CHELATE OF THE MONOSODIUM SALT OF (ETHYLENEDINITRILO)TETRAACETIC ACID
Common Name English
SODIUM IRON EDTA
FCC   USP-RS  
Common Name English
SODIUM IRON EDTA [USP-RS]
Common Name English
ETHYLENEDIAMINETETRAACETIC ACID FERRIC SODIUM SALT
Common Name English
SODIUM IRON EDTA [FCC]
Common Name English
sodium feredetate [INN]
Common Name English
FERRIC SODIUM EDETATE [MI]
Common Name English
Sodium feredetate [WHO-DD]
Common Name English
EDTA, IRON (III) SODIUM
Common Name English
NSC-5237
Code English
FERRAZONE
Brand Name English
IRON(III) SODIUM ETHYLENEDIAMINE TETRAACETATE
Systematic Name English
EDTA IRON(III) SODIUM SALT
Common Name English
SYBRON
Brand Name English
Classification Tree Code System Code
WHO-ATC B03AB03
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
EPA PESTICIDE CODE 139114
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
WHO-VATC QB03AB03
Created by admin on Sun Dec 18 21:20:42 UTC 2022 , Edited by admin on Sun Dec 18 21:20:42 UTC 2022
Code System Code Type Description
DAILYMED
403J23EMFA
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
NCI_THESAURUS
C76827
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
GRAS Notification (GRN No.)
152
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
GRAS Notification (GRN No.)
178
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
WIKIPEDIA
Ferric sodium EDTA
Created by admin on Sun Dec 18 21:20:42 UTC 2022 , Edited by admin on Sun Dec 18 21:20:42 UTC 2022
PRIMARY
INN
1122
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
NSC
5237
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
CHEBI
78292
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
FDA UNII
403J23EMFA
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
EVMPD
SUB10560MIG
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
DRUG CENTRAL
4709
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
MERCK INDEX
M5328
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY Merck Index
DRUG BANK
DB13381
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
RXCUI
105673
Created by admin on Sun Dec 18 21:20:42 UTC 2022 , Edited by admin on Sun Dec 18 21:20:42 UTC 2022
PRIMARY RxNorm
EPA CompTox
DTXSID5027774
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
ECHA (EC/EINECS)
239-802-2
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
NCI_THESAURUS
C1505
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
CONCEPT Dietary Supplement
RS_ITEM_NUM
1614239
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
CAS
15708-41-5
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
PUBCHEM
27461
Created by admin on Sun Dec 18 21:20:41 UTC 2022 , Edited by admin on Sun Dec 18 21:20:41 UTC 2022
PRIMARY
Related Record Type Details
Structure of FERRIC CATION
PARENT -> SALT/SOLVATE
Structure of EDETIC ACID
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of FERRIC CATION
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