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Details

Stereochemistry ACHIRAL
Molecular Formula Fe.O.HO.H2O
Molecular Weight 106.867
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERRIC OXIDE YELLOW

SMILES

O.[OH-].[O--].[Fe+3]

InChI

InChIKey=LDHBWEYLDHLIBQ-UHFFFAOYSA-M
InChI=1S/Fe.2H2O.O/h;2*1H2;/q+3;;;-2/p-1

HIDE SMILES / InChI
Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including http://www.mfc.co.jp/english/eng/product/sanferol/index.html

Ferric Ammonium EDTA Solution is normally used as a photographic chemical for a bleaching agent in the process of colour washing. It is also used as a complexing, and oxidizing agent & as a fertilizer and catalyst. EDTA acid are colourless, water-soluble solid that are widely used to dissolve scale. The usefulness of these ammonium salts arise because of its role as a chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+.

Originator

Monsanto Chemicals
40
Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

1921
1468
Targets

Targets

Primary TargetPharmacologyConditionPotency
Activator
1447
Chelating Agent
139
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Basic research
Unknown

Approved Use

Unknown
Primary
Approved
8583
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Approved
8583
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

1998
Palliative
Approved
8583
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

2014
PubMed

PubMed

TitleDatePubMed
The absorption of iron as supplements in infant cereal and infant formulas.
1975 May
Contact dermatitis to yellow iron oxide.
1985 Aug
Patents

Patents

20090216060
40
6258758
40
US 5206265 A
40
US2385188
40
US4364871
40
US6881255
40
US6903235
40
US7198668
40

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Bovine enamel was treated with 10 mM FeF3 (Ferric fluoride)
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:04:29 GMT 2025
Edited
by admin
on Mon Mar 31 18:04:29 GMT 2025
Record UNII
EX438O2MRT
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
CI 77492
INCI  
INCI  
Preferred Name English
FERRIC OXIDE YELLOW
II  
Common Name English
C.I. PIGMENT YELLOW 42
Common Name English
FERRIC OXIDE, YELLOW
Common Name English
INS NO.172(III)
Common Name English
YELLOW IRON OXIDE
Common Name English
FERRIC OXIDE (HYDRATE) [NF]
Common Name English
IRON(III) OXIDE-HYDROXIDE MONOHYDRATE
Common Name English
YELLOW FERRIC OXIDE
Common Name English
FERROX
Brand Name English
FERRIC OXIDE,YELLOW [VANDF]
Common Name English
IRON OXIDE YELLOW
Common Name English
C.I. 77492
Common Name English
IRON OXIDE,YELLOW [VANDF]
Common Name English
FERRIC OXIDE YELLOW [II]
Common Name English
FERRIC OXYHYDROXIDE HYDRATE
Common Name English
PIGMENT YELLOW 42
Common Name English
FERRIC OXIDE HYDRATE
Common Name English
MAPICO YELLOW
Common Name English
HYDRATED IRON (III) OXIDE
Common Name English
HYDRATED FERRIC-OXIDE
Common Name English
HYDROUS FERRIC OXIDE
Common Name English
CI PIGMENT YELLOW 42 AND 43
Common Name English
E-172(III)
Common Name English
FERRIC OXIDE,YELLOW
VANDF  
Common Name English
FERRIC OXIDE, HYDRATED [II]
Common Name English
HYDRATED FERRIC OXIDE
Common Name English
IRON OXIDE,YELLOW
VANDF  
Common Name English
INS-172(III)
Common Name English
CI(1975) NO. 77492
Common Name English
FERRIC OXIDE, HYDRATED
II  
Common Name English
SYNTHETIC YELLOW IRON OXIDE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C461
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
JECFA EVALUATION INS-172(III)
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
CODEX ALIMENTARIUS (GSFA) INS-172(III)
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
Code System Code Type Description
FDA UNII
EX438O2MRT
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
PRIMARY
PUBCHEM
23320441
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
PRIMARY
SMS_ID
100000076429
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
PRIMARY
MESH
C000499
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
PRIMARY
WIKIPEDIA
IRON(III) OXIDE-HYDROXIDE
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
PRIMARY
RXCUI
1305582
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
PRIMARY
NCI_THESAURUS
C75671
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
PRIMARY
RXCUI
1305585
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
ALTERNATIVE
ECHA (EC/EINECS)
257-098-5
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
PRIMARY
CAS
1317-63-1
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
ALTERNATIVE
EVMPD
SUB127153
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
PRIMARY
CAS
51274-00-1
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
PRIMARY
EVMPD
SUB15934MIG
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
PRIMARY
DAILYMED
EX438O2MRT
Created by admin on Mon Mar 31 18:04:29 GMT 2025 , Edited by admin on Mon Mar 31 18:04:29 GMT 2025
PRIMARY
Related Record Type Details
YELLOW OCHRE
SUB_CONCEPT->SUBSTANCE
Structure of FERRIC OXYHYDROXIDE
ANHYDROUS->SOLVATE
Structure of FERRIC CATION
PARENT -> SALT/SOLVATE
NIH
NCATS
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