U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula Fe.O.HO.H2O
Molecular Weight 106.867
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERRIC OXIDE YELLOW

SMILES

O.[OH-].[O--].[Fe+3]

InChI

InChIKey=LDHBWEYLDHLIBQ-UHFFFAOYSA-M
InChI=1S/Fe.2H2O.O/h;2*1H2;/q+3;;;-2/p-1

HIDE SMILES / InChI
Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Sources: https://books.google.ru/books?id=vxtxWneRBN4C&pg=PA1103&#v=onepage&q&f=falsehttps://mistralhowto.wordpress.com/2012/03/12/what-is-pigment-yellow-42-and-what-is-it-used-for/ | http://sensientfoodcolors.com/en-us/confection/iron-oxides-approved-by-the-fda/ | https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=73.2250 | https://www.drugs.com/inactive/ferric-oxide-yellow-381.htmlhttp://www.mfc.co.jp/english/eng/product/sanferol/pdf/fls_gras_notice.pdfhttps://www.accessdata.fda.gov/drugsatfda_docs/nda/2014/205874Orig1s000PharmR.pdfhttps://cameochemicals.noaa.gov/chemical/3468 | https://www.ncbi.nlm.nih.gov/pubmed/2135524http://www.edta-chelate.com/ferric-ammonium-edta-liquid--1640836.htmlhttps://books.google.ru/books?id=3hLmyma2-MsC&pg=PA241&lpg=PA241&dq=FERRIC+AMMONIUM+CHLORIDE retrieved from A Consumer's Dictionary of Cosmetic Ingredients, 7th Edition: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics and Cosmeceuticals By Ruth Winterhttps://www.ncbi.nlm.nih.gov/pubmed/27995746 | http://onlinelibrary.wiley.com/doi/10.1002/047084289X.rn01568/abstract?userIsAuthenticated=false&deniedAccessCustomisedMessage=
Curator's Comment: description was created based on several sources, including http://www.mfc.co.jp/english/eng/product/sanferol/index.html

Ferric bromide, red-brown odorless compound, an oxidizing reagent, used as a catalyst for organic reactions, particularly in bromination of aromatic compounds.

Originator

Monsanto Chemicals
43
Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

1921
1447
Targets

Targets

Primary TargetPharmacologyConditionPotency
Activator
1404
Chelating Agent
143
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Basic research
Unknown

Approved Use

Unknown
Primary
Approved
8307
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Approved
8307
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

9.0935997E11
Curative
Approved
8307
RADIOGARDASE

Approved Use

Insoluble Prussian blue is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination.

Launch Date

1.06496642E12
Palliative
Approved
8307
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

1.40978881E12
PubMed

PubMed

TitleDatePubMed
Fabrication of FeF3 Nanoflowers on CNT branches and their application to high power lithium rechargeable batteries.
2010 Dec 7
Microwave assisted convenient one-pot synthesis of coumarin derivatives via Pechmann condensation catalyzed by FeF3 under solvent-free conditions and antimicrobial activities of the products.
2014 Aug 26
FeF(3) catalyzed cascade C-C and C-N bond formation: synthesis of differentially substituted triheterocyclic benzothiazole functionalities under solvent-free condition.
2014 May
Heme Binding by Corynebacterium diphtheriae HmuT: Function and Heme Environment.
2015 Nov 3
Superior electrochemical performance of N-doped nanocrystalline FeF(3)/C with a single-step solid-state process.
2016 Oct 4
Phosphorus recovery from biogas slurry by ultrasound/H(2)O(2) digestion coupled with HFO/biochar adsorption process.
2017 Feb
A Simplified Fe-Based PhotoATRP Using Only Monomers and Solvent.
2017 Jul
Patents

Patents

20080188032
43
20090216060
43
6258758
43
US 5206265 A
43
US2385188
43
US4364871
43
US6881255
43
US6903235
43
US7198668
43

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
As a food supplement, ferric sodium pyrophosphate is administered orally.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 16 17:45:50 UTC 2022
Edited
by admin
on Fri Dec 16 17:45:50 UTC 2022
Record UNII
EX438O2MRT
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
FERRIC OXIDE YELLOW
II  
Common Name English
C.I. PIGMENT YELLOW 42
Common Name English
FERRIC OXIDE, YELLOW
Common Name English
INS NO.172(III)
Common Name English
YELLOW IRON OXIDE
Common Name English
FERRIC OXIDE (HYDRATE) [NF]
Common Name English
IRON(III) OXIDE-HYDROXIDE MONOHYDRATE
Common Name English
YELLOW FERRIC OXIDE
Common Name English
FERROX
Brand Name English
FERRIC OXIDE,YELLOW [VANDF]
Common Name English
IRON OXIDE YELLOW
Common Name English
C.I. 77492
Common Name English
CI 77492
INCI  
INCI  
Official Name English
IRON OXIDE,YELLOW [VANDF]
Common Name English
FERRIC OXIDE YELLOW [II]
Common Name English
FERRIC OXYHYDROXIDE HYDRATE
Common Name English
PIGMENT YELLOW 42
Common Name English
FERRIC OXIDE HYDRATE
Common Name English
MAPICO YELLOW
Common Name English
HYDRATED IRON (III) OXIDE
Common Name English
HYDRATED FERRIC-OXIDE
Common Name English
HYDROUS FERRIC OXIDE
Common Name English
CI PIGMENT YELLOW 42 AND 43
Common Name English
E-172(III)
Common Name English
CI 77492 [INCI]
Common Name English
FERRIC OXIDE,YELLOW
VANDF  
Common Name English
FERRIC OXIDE, HYDRATED [II]
Common Name English
HYDRATED FERRIC OXIDE
Common Name English
IRON OXIDE,YELLOW
VANDF  
Common Name English
INS-172(III)
Common Name English
CI(1975) NO. 77492
Common Name English
FERRIC OXIDE, HYDRATED
II  
Common Name English
SYNTHETIC YELLOW IRON OXIDE
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C461
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
JECFA EVALUATION INS-172(III)
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
CODEX ALIMENTARIUS (GSFA) INS-172(III)
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
Code System Code Type Description
FDA UNII
EX438O2MRT
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
PRIMARY
PUBCHEM
23320441
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
PRIMARY
MESH
C000499
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
PRIMARY
WIKIPEDIA
IRON(III) OXIDE-HYDROXIDE
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
PRIMARY
EPA CompTox
DTXSID8093607
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
PRIMARY
JECFA MONOGRAPH
INS-172(III)
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
PRIMARY
RXCUI
1305582
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
PRIMARY
NCI_THESAURUS
C75671
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
PRIMARY
RXCUI
1305585
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
ALTERNATIVE
ECHA (EC/EINECS)
257-098-5
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
PRIMARY
CAS
1317-63-1
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
ALTERNATIVE
EVMPD
SUB127153
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
PRIMARY
CAS
51274-00-1
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
PRIMARY
EVMPD
SUB15934MIG
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
PRIMARY
DAILYMED
EX438O2MRT
Created by admin on Fri Dec 16 17:45:50 UTC 2022 , Edited by admin on Fri Dec 16 17:45:50 UTC 2022
PRIMARY
Related Record Type Details
YELLOW OCHRE
SUB_CONCEPT->SUBSTANCE
Structure of FERRIC OXYHYDROXIDE
ANHYDROUS->SOLVATE
Structure of FERRIC CATION
PARENT -> SALT/SOLVATE
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966