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Details

Stereochemistry ACHIRAL
Molecular Formula C6H6NO6.Fe
Molecular Weight 243.96
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERRIC NITRILOTRIACETATE

SMILES

[Fe+3].[O-]C(=O)CN(CC([O-])=O)CC([O-])=O

InChI

InChIKey=FXDLIMJMHVKXAR-UHFFFAOYSA-K
InChI=1S/C6H9NO6.Fe/c8-4(9)1-7(2-5(10)11)3-6(12)13;/h1-3H2,(H,8,9)(H,10,11)(H,12,13);/q;+3/p-3

HIDE SMILES / InChI

Molecular Formula C6H6NO6
Molecular Weight 188.1149
Charge -3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Effect of dietary vitamin E on ferric nitrilotriacetate-induced nephrotoxicity in rats.
1988 Mar 15
Transforming growth factor-alpha expression of renal proximal tubules in Wistar rats treated with ferric and aluminum nitrilotriacetate.
1993 Jun
MAP kinase-independent induction of proto-oncogene c-fos mRNA by hemin in human cells.
1999 Jun 24
Molecular mechanisms by which iron induces nitric oxide synthesis in cultured proximal tubule cells.
2001
Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity.
2002 Jul 1
Protective effect of metallothionein-III on DNA damage in response to reactive oxygen species.
2002 Oct 10
Cytoglobin overexpression protects against damage-induced fibrosis.
2006 Jun
Coordinated induction of Nrf2 target genes protects against iron nitrilotriacetate (FeNTA)-induced nephrotoxicity.
2008 Sep 15
Oxidative changes in the rat brain by intraperitoneal injection of ferric nitrilotriacetate.
2009
Protective role of glutathione S-transferase A4 induced in copper/zinc-superoxide dismutase knockout mice.
2009 Sep 1
Substance Class Chemical
Created
by admin
on Fri Dec 15 19:46:50 GMT 2023
Edited
by admin
on Fri Dec 15 19:46:50 GMT 2023
Record UNII
Z3U5ED15B9
Record Status Validated (UNII)
Record Version
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Name Type Language
FERRIC NITRILOTRIACETATE
HSDB  
Common Name English
IRON, (N,N-BIS((CARBOXY-.KAPPA.O)METHYL)GLYCINATO(3-)-.KAPPA.N,.KAPPA.O)-, (T-4)-
Systematic Name English
FERRIC NITRILOTRIACETATE [HSDB]
Common Name English
FE(III)-NTA COMPLEX (1:1
Common Name English
IRON(III) NITRILOTRIACETATE
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID60167764
Created by admin on Fri Dec 15 19:46:50 GMT 2023 , Edited by admin on Fri Dec 15 19:46:50 GMT 2023
PRIMARY
FDA UNII
Z3U5ED15B9
Created by admin on Fri Dec 15 19:46:50 GMT 2023 , Edited by admin on Fri Dec 15 19:46:50 GMT 2023
PRIMARY
HSDB
1306
Created by admin on Fri Dec 15 19:46:50 GMT 2023 , Edited by admin on Fri Dec 15 19:46:50 GMT 2023
PRIMARY
PUBCHEM
27880
Created by admin on Fri Dec 15 19:46:50 GMT 2023 , Edited by admin on Fri Dec 15 19:46:50 GMT 2023
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MESH
C020326
Created by admin on Fri Dec 15 19:46:50 GMT 2023 , Edited by admin on Fri Dec 15 19:46:50 GMT 2023
PRIMARY
CAS
16448-54-7
Created by admin on Fri Dec 15 19:46:50 GMT 2023 , Edited by admin on Fri Dec 15 19:46:50 GMT 2023
PRIMARY
CHEBI
132238
Created by admin on Fri Dec 15 19:46:50 GMT 2023 , Edited by admin on Fri Dec 15 19:46:50 GMT 2023
PRIMARY
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