Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H6NO6.Fe |
| Molecular Weight | 243.96 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[Fe+3].[O-]C(=O)CN(CC([O-])=O)CC([O-])=O
InChI
InChIKey=FXDLIMJMHVKXAR-UHFFFAOYSA-K
InChI=1S/C6H9NO6.Fe/c8-4(9)1-7(2-5(10)11)3-6(12)13;/h1-3H2,(H,8,9)(H,10,11)(H,12,13);/q;+3/p-3
| Molecular Formula | C6H6NO6 |
| Molecular Weight | 188.1149 |
| Charge | -3 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | Fe |
| Molecular Weight | 55.845 |
| Charge | 3 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Effect of dietary vitamin E on ferric nitrilotriacetate-induced nephrotoxicity in rats. | 1988 Mar 15 |
|
| Mechanism of iron potentiation of hepatic uroporphyria: studies in cultured chick embryo liver cells. | 1989 Sep |
|
| Overexpression of integrin-associated protein (CD47) in rat kidney treated with a renal carcinogen, ferric nitrilotriacetate. | 1997 Feb |
|
| Ferric nitrilotriacetate promotes N-diethylnitrosamine-induced renal tumorigenesis in the rat: implications for the involvement of oxidative stress. | 1998 Jun |
|
| MAP kinase-independent induction of proto-oncogene c-fos mRNA by hemin in human cells. | 1999 Jun 24 |
|
| Iron inhibits the nitric oxide synthesis elicited by asbestos in murine macrophages. | 2001 Aug 1 |
|
| Effect of nitric oxide on iron-mediated cytotoxicity in primary cultured renal proximal tubules. | 2001 Dec |
|
| Iron treatment downregulates DMT1 and IREG1 mRNA expression in Caco-2 cells. | 2002 Apr |
|
| Doxorubicin induces an increase of nitric oxide synthesis in rat cardiac cells that is inhibited by iron supplementation. | 2002 Dec 1 |
|
| Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity. | 2002 Jul 1 |
|
| Protective effect of metallothionein-III on DNA damage in response to reactive oxygen species. | 2002 Oct 10 |
|
| Suppressive effects of Active Hexose Correlated Compound on the increased activity of hepatic and renal ornithine decarboxylase induced by oxidative stress. | 2003 Dec 19 |
|
| Vitamin E inhibits hepatic oxidative stress, toxicity and hyperproliferation in rats treated with the renal carcinogen ferric nitrilotriacetate. | 2005 |
|
| Induction of hepatic and renal metallothionein synthesis by ferric nitrilotriacetate in mice: the role of MT as an antioxidant. | 2005 Apr 1 |
|
| Two distinct mechanisms for loss of thioredoxin-binding protein-2 in oxidative stress-induced renal carcinogenesis. | 2005 Jun |
|
| Inhibitory effects of idoxifene on hepatic fibrosis in rats. | 2005 May |
|
| Susceptibility of actin to modification by 4-hydroxy-2-nonenal. | 2005 Nov 15 |
|
| Cytoglobin overexpression protects against damage-induced fibrosis. | 2006 Jun |
|
| Oxidative stress induces phosphoenolpyruvate carboxykinase expression in H4IIE cells. | 2006 Sep |
|
| Alpha-tocopherol induces calnexin in renal tubular cells: another protective mechanism against free radical-induced cellular damage. | 2006 Sep 15 |
|
| Effect of melatonin, curcumin, quercetin, and resveratrol on acute ferric nitrilotriacetate (Fe-NTA)-induced renal oxidative damage in rats. | 2008 Apr |
|
| Oxidative changes in the rat brain by intraperitoneal injection of ferric nitrilotriacetate. | 2009 |
|
| Protective role of glutathione S-transferase A4 induced in copper/zinc-superoxide dismutase knockout mice. | 2009 Sep 1 |
|
| Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways. | 2011 Nov 28 |
|
| Aberrant activation of ubiquitin D at G2 phase and apoptosis by carcinogens that evoke cell proliferation after 28-day administration in rats. | 2012 |
|
| Oxidation and turnover of renal metallothioneins after an injection of ferric nitrilotriacetate. | 2012 Jan 5 |
|
| Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: plausible role of NF-κB. | 2013 Feb 4 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 17 03:39:09 UTC 2022
by
admin
on
Sat Dec 17 03:39:09 UTC 2022
|
| Record UNII |
Z3U5ED15B9
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
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DTXSID60167764
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Z3U5ED15B9
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1306
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27880
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C020326
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16448-54-7
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132238
Created by
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PARENT -> SALT/SOLVATE |
