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Details

Stereochemistry ACHIRAL
Molecular Formula C6H5O7.Fe
Molecular Weight 244.945
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERRIC CITRATE ANHYDROUS

SMILES

[Fe+3].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O

InChI

InChIKey=NPFOYSMITVOQOS-UHFFFAOYSA-K
InChI=1S/C6H8O7.Fe/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+3/p-3

HIDE SMILES / InChI

Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C6H5O7
Molecular Weight 189.0997
Charge -3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Ferric Ammonium EDTA Solution is normally used as a photographic chemical for a bleaching agent in the process of colour washing. It is also used as a complexing, and oxidizing agent & as a fertilizer and catalyst. EDTA acid are colourless, water-soluble solid that are widely used to dissolve scale. The usefulness of these ammonium salts arise because of its role as a chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+.

Originator

Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

1998
Palliative
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

2014
PubMed

PubMed

TitleDatePubMed
The absorption of iron as supplements in infant cereal and infant formulas.
1975 May
New phosphate binding agents: ferric compounds.
1999 Jun
Fabrication of FeF3 Nanoflowers on CNT branches and their application to high power lithium rechargeable batteries.
2010 Dec 7
Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions.
2011 Jun
Microwave assisted convenient one-pot synthesis of coumarin derivatives via Pechmann condensation catalyzed by FeF3 under solvent-free conditions and antimicrobial activities of the products.
2014 Aug 26
FeF(3) catalyzed cascade C-C and C-N bond formation: synthesis of differentially substituted triheterocyclic benzothiazole functionalities under solvent-free condition.
2014 May
Heme Binding by Corynebacterium diphtheriae HmuT: Function and Heme Environment.
2015 Nov 3
Patents

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Bovine enamel was treated with 10 mM FeF3 (Ferric fluoride)
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:06:52 GMT 2025
Edited
by admin
on Mon Mar 31 18:06:52 GMT 2025
Record UNII
63G354M39Z
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERRIC CITRATE ANHYDROUS
Common Name English
FERRIC CITRATE
FCC   INCI   MI   WHO-DD  
INCI  
Preferred Name English
NSC-112227
Code English
FERRIC CITRATE [ORANGE BOOK]
Common Name English
Ferric citrate [WHO-DD]
Common Name English
IRON(III) CITRATE
Systematic Name English
FERRIC CITRATE [FCC]
Common Name English
IRON CITRATE
Systematic Name English
FERRIC CITRATE [MI]
Common Name English
1,2,3-PROPANETRICARBOXYLIC ACID, 2-HYDROXY-, IRON SALT
Common Name English
1,2,3-PROPANETRICARBOXYLIC ACID, 2-HYDROXY-, IRON(3+) SALT (1:1)
Common Name English
FERRUM CITRICUM [HPUS]
Common Name English
FERRUM CITRICUM
HPUS  
Common Name English
IRON(III) CITRATE TRIBASIC
Common Name English
2-HYDROXY-1,2,3-PROPANETRICARBOXYLIC ACID IRON SALT
Common Name English
JTT-751
Code English
Classification Tree Code System Code
CFR 21 CFR 184.1298
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
WHO-ATC B03AB06
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
WHO-ATC V03AE08
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
WHO-VATC QB03AB06
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
Code System Code Type Description
LACTMED
Ferric Citrate
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
DAILYMED
63G354M39Z
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
RXCUI
1594675
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY RxNorm
PUBCHEM
61300
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
ECHA (EC/EINECS)
222-536-6
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
ECHA (EC/EINECS)
219-045-4
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
ALTERNATIVE
EVMPD
SUB13838MIG
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
SMS_ID
100000078721
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
DRUG CENTRAL
4538
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
EPA CompTox
DTXSID0037657
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
CHEBI
144421
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
CAS
2338-05-8
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
NON-SPECIFIC STOICHIOMETRY
FDA UNII
63G354M39Z
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
WIKIPEDIA
Ferric citrate
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
ECHA (EC/EINECS)
249-117-0
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
ALTERNATIVE
CAS
28633-45-6
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
NON-SPECIFIC STOICHIOMETRY
ChEMBL
CHEMBL3301597
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
NSC
112227
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
MERCK INDEX
m5318
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY Merck Index
CAS
3522-50-7
Created by admin on Mon Mar 31 18:06:52 GMT 2025 , Edited by admin on Mon Mar 31 18:06:52 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
SOLVATE->ANHYDROUS
SOLVATE->ANHYDROUS
SOLVATE->ANHYDROUS
PARENT -> SALT/SOLVATE
SOLVATE->ANHYDROUS
Related Record Type Details
ACTIVE MOIETY