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Details

Stereochemistry ACHIRAL
Molecular Formula 4Fe.3O7P2
Molecular Weight 745.21
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERRIC PYROPHOSPHATE

SMILES

[Fe+3].[Fe+3].[Fe+3].[Fe+3].[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O

InChI

InChIKey=CADNYOZXMIKYPR-UHFFFAOYSA-B
InChI=1S/4Fe.3H4O7P2/c;;;;3*1-8(2,3)7-9(4,5)6/h;;;;3*(H2,1,2,3)(H2,4,5,6)/q4*+3;;;/p-12

HIDE SMILES / InChI
Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula O7P2
Molecular Weight 173.9433
Charge -4
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Sources: https://books.google.ru/books?id=vxtxWneRBN4C&pg=PA1103&#v=onepage&q&f=falsehttps://mistralhowto.wordpress.com/2012/03/12/what-is-pigment-yellow-42-and-what-is-it-used-for/ | http://sensientfoodcolors.com/en-us/confection/iron-oxides-approved-by-the-fda/ | https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=73.2250 | https://www.drugs.com/inactive/ferric-oxide-yellow-381.htmlhttp://www.mfc.co.jp/english/eng/product/sanferol/pdf/fls_gras_notice.pdfhttps://www.accessdata.fda.gov/drugsatfda_docs/nda/2014/205874Orig1s000PharmR.pdfhttps://cameochemicals.noaa.gov/chemical/3468 | https://www.ncbi.nlm.nih.gov/pubmed/2135524http://www.edta-chelate.com/ferric-ammonium-edta-liquid--1640836.htmlhttps://books.google.ru/books?id=3hLmyma2-MsC&pg=PA241&lpg=PA241&dq=FERRIC+AMMONIUM+CHLORIDE retrieved from A Consumer's Dictionary of Cosmetic Ingredients, 7th Edition: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics and Cosmeceuticals By Ruth Winterhttps://www.ncbi.nlm.nih.gov/pubmed/27995746 | http://onlinelibrary.wiley.com/doi/10.1002/047084289X.rn01568/abstract?userIsAuthenticated=false&deniedAccessCustomisedMessage=
Curator's Comment: description was created based on several sources, including http://www.mfc.co.jp/english/eng/product/sanferol/index.html

Ferric bromide, red-brown odorless compound, an oxidizing reagent, used as a catalyst for organic reactions, particularly in bromination of aromatic compounds.

Originator

Monsanto Chemicals
43
Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

1921
1447
Targets

Targets

Primary TargetPharmacologyConditionPotency
Activator
1404
Chelating Agent
143
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Basic research
Unknown

Approved Use

Unknown
Primary
Approved
8307
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Approved
8307
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

9.0935997E11
Curative
Approved
8307
RADIOGARDASE

Approved Use

Insoluble Prussian blue is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination.

Launch Date

1.06496642E12
Palliative
Approved
8307
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

1.40978881E12
PubMed

PubMed

TitleDatePubMed
The formation of ferritin from apoferritin. Kinetics and mechanism of iron uptake.
1972 Jan
The absorption of iron as supplements in infant cereal and infant formulas.
1975 May
Carcinogenicity studies on natural and man-made fibres with the intraperitoneal test in rats.
1989
Non-invasive and non-destructive micro-XRF and micro-Raman analysis of a decorative wallpaper from the beginning of the 19th century.
2007 Feb
Metal-mediated cyclization of aryl and benzyl glycidyl ethers: a complete scenario.
2008 Dec 17
Fabrication of FeF3 Nanoflowers on CNT branches and their application to high power lithium rechargeable batteries.
2010 Dec 7
Oxidative aromatic C-N bond formation: convenient synthesis of N-amino-3-nitrile-indoles via FeBr3-mediated intramolecular cyclization.
2011 May 21
Finnish wallpaper pigments in the 18th-19th century: presence of KFe3(CrO4)2(OH)6 and odd pigment mixtures.
2013 Apr
FeF(3) catalyzed cascade C-C and C-N bond formation: synthesis of differentially substituted triheterocyclic benzothiazole functionalities under solvent-free condition.
2014 May
Nazarov cyclization of 1,4-pentadien-3-ols: preparation of cyclopenta[b]indoles and spiro[indene-1,4'-quinoline]s.
2016 Feb 14
Mechanisms and origins of the switchable regioselectivity of FeBr3-catalyzed [1,2]-aryl and [1,2]-alkyl shifts of α-aryl aldehydes.
2016 Feb 28
Superior electrochemical performance of N-doped nanocrystalline FeF(3)/C with a single-step solid-state process.
2016 Oct 4
A Simplified Fe-Based PhotoATRP Using Only Monomers and Solvent.
2017 Jul
Patents

Patents

20080188032
43
20090216060
43
6258758
43
US 5206265 A
43
US2385188
43
US4364871
43
US6881255
43
US6903235
43
US7198668
43

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
As a food supplement, ferric sodium pyrophosphate is administered orally.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 16 17:51:42 UTC 2022
Edited
by admin
on Fri Dec 16 17:51:42 UTC 2022
Record UNII
QK8899250F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERRIC PYROPHOSPHATE
FCC   HSDB   MART.   MI   VANDF   WHO-DD  
Common Name English
FERRIC PYROPHOSPHATE [VANDF]
Common Name English
DIPHOSPHORIC ACID IRON(3+) SALT (3:4)
Common Name English
IRON (AS PYROPHOSPHATE)
Common Name English
FERRIC PYROPHOSPHATE [FCC]
Common Name English
IRON(III) PYROPHOSPHATE
Common Name English
FERRIC PYROPHOSPHATE [HSDB]
Common Name English
Ferric pyrophosphate [WHO-DD]
Common Name English
FERRIC PYROPHOSPHATE [MART.]
Common Name English
FERRIC PYROPHOSPHATE [MI]
Common Name English
Classification Tree Code System Code
CFR 21 CFR 184.1304
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
Code System Code Type Description
RXCUI
1607976
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY RxNorm
EVMPD
SUB13847MIG
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY
CHEBI
132767
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY
NCI_THESAURUS
C82284
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY
DRUG BANK
DB09147
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY
MERCK INDEX
M5327
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY Merck Index
NCI_THESAURUS
C45678
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
CONCEPT Industrial Aid
ECHA (EC/EINECS)
233-190-0
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY
DAILYMED
QK8899250F
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY
WIKIPEDIA
Iron(III) pyrophosphate
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY
EPA CompTox
DTXSID6047600
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY
HSDB
454
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY
CAS
10058-44-3
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY
MESH
C049051
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY
FDA UNII
QK8899250F
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY
PUBCHEM
24877
Created by admin on Fri Dec 16 17:51:42 UTC 2022 , Edited by admin on Fri Dec 16 17:51:42 UTC 2022
PRIMARY
Related Record Type Details
Structure of FERRIC CATION
PARENT -> SALT/SOLVATE
Structure of PYROPHOSPHORIC ACID
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of FERRIC CATION
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