U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula 5C12H22O11.C6H11O7.2Fe.Na.3O
Molecular Weight 2089.308
Optical Activity UNSPECIFIED
Defined Stereocenters 49 / 49
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM FERRIC GLUCONATE COMPLEX

SMILES

[O--].[O--].[O--].[Na+].[Fe+3].[Fe+3].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@H]1O[C@@](CO)(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O.OC[C@H]3O[C@@](CO)(O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](O)[C@@H]3O.OC[C@H]5O[C@@](CO)(O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)[C@@H]5O.OC[C@H]7O[C@@](CO)(O[C@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@@H]7O.OC[C@H]9O[C@@](CO)(O[C@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@@H](O)[C@@H]9O

InChI

InChIKey=MQBDAEHWGRMADS-XNHLMZCASA-M
InChI=1S/5C12H22O11.C6H12O7.2Fe.Na.3O/c5*13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12;7-1-2(8)3(9)4(10)5(11)6(12)13;;;;;;/h5*4-11,13-20H,1-3H2;2-5,7-11H,1H2,(H,12,13);;;;;;/q;;;;;;2*+3;+1;3*-2/p-1/t5*4-,5-,6-,7-,8+,9-,10+,11-,12+;2-,3-,4+,5-;;;;;;/m111111....../s1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C6H8O7
Molecular Weight 192.1235
Charge -4
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula C12H22O11
Molecular Weight 342.2965
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 9 / 9
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Originator

Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

9.0935997E11
Curative
RADIOGARDASE

Approved Use

Insoluble Prussian blue is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination.

Launch Date

1.06496642E12
Palliative
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

1.40978881E12
PubMed

PubMed

TitleDatePubMed
The formation of ferritin from apoferritin. Catalytic action of apoferritin.
1973 Oct
The absorption of iron as supplements in infant cereal and infant formulas.
1975 May
Contact dermatitis to yellow iron oxide.
1985 Aug
Carcinogenicity studies on natural and man-made fibres with the intraperitoneal test in rats.
1989
Effect of physical exercise and vitamin C on absorption of ferric sodium citrate.
1996 Dec
New phosphate binding agents: ferric compounds.
1999 Jun
Non-invasive and non-destructive micro-XRF and micro-Raman analysis of a decorative wallpaper from the beginning of the 19th century.
2007 Feb
Interaction of omapatrilat with FD&C Blue No. 2 lake during dissolution of modified release tablets.
2007 Jul 18
Oxidative aromatic C-N bond formation: convenient synthesis of N-amino-3-nitrile-indoles via FeBr3-mediated intramolecular cyclization.
2011 May 21
Microwave assisted convenient one-pot synthesis of coumarin derivatives via Pechmann condensation catalyzed by FeF3 under solvent-free conditions and antimicrobial activities of the products.
2014 Aug 26
FeF(3) catalyzed cascade C-C and C-N bond formation: synthesis of differentially substituted triheterocyclic benzothiazole functionalities under solvent-free condition.
2014 May
Halide Influence on Molecular and Supramolecular Arrangements of Iron Complexes with a 3,5-Bis(2-Pyridyl)-1,2,4,6-Thiatriazine Ligand.
2016 Jun 6
Iron-Catalyzed Regioselective Transfer Hydrogenative Couplings of Unactivated Aldehydes with Simple Alkenes.
2016 May 17
A Simplified Fe-Based PhotoATRP Using Only Monomers and Solvent.
2017 Jul
Patents

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
As a food supplement, ferric sodium pyrophosphate is administered orally.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 16 18:58:47 UTC 2022
Edited
by admin
on Fri Dec 16 18:58:47 UTC 2022
Record UNII
CC9149U2QX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM FERRIC GLUCONATE COMPLEX
MART.   MI   ORANGE BOOK   USAN  
USAN  
Official Name English
SODIUM FERRIC GLUCONATE
Common Name English
FERRLECIT
Brand Name English
SODIUM FERRIC GLUCONATE COMPLEX [MART.]
Common Name English
FERRIC NA GLUCONATE
VANDF  
Common Name English
SODIUM FERRIC GLUCONATE COMPLEX [USAN]
Common Name English
Ferric sodium gluconate complex [WHO-DD]
Common Name English
IRON SODIUM GLUCONATE
Common Name English
SODIUM FERRIGLUCONATE
Common Name English
SODIUM FERRIC GLUCONATE COMPLEX [ORANGE BOOK]
Common Name English
OSMOFERRIN
Brand Name English
FERRIC SODIUM GLUCONATE COMPLEX
WHO-DD  
Common Name English
FERRIC NA GLUCONATE COMPLEX [VANDF]
Common Name English
FERRIC NA GLUCONATE [VANDF]
Common Name English
FERRIC SODIUM GLUCONATE
Common Name English
SODIUM FERRIC GLUCONATE COMPLEX [MI]
Common Name English
FERLIXIT
Brand Name English
FERRIC NA GLUCONATE COMPLEX
VANDF  
Common Name English
IRON (SODIUM FERRIC GLUCONATE COMPLEX IN SUCROSE INJECTION)
Common Name English
Classification Tree Code System Code
NDF-RT N0000177913
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
NDF-RT N0000006237
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
NDF-RT N0000006237
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
NDF-RT N0000006237
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
Code System Code Type Description
CAS
34089-81-1
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
NON-SPECIFIC STOICHIOMETRY
NCI_THESAURUS
C77274
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY
DRUG BANK
DB09517
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY
DAILYMED
CC9149U2QX
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY
LACTMED
Sodium Ferric Gluconate Complex
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY
EVMPD
SUB13850MIG
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY
EVMPD
SUB20743
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY
EPA CompTox
DTXSID80187686
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY
ChEMBL
CHEMBL1201494
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY
RXCUI
261435
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY RxNorm
USAN
KK-97
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY
NCI_THESAURUS
C1505
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
CONCEPT Dietary Supplement
WIKIPEDIA
Sodium ferric gluconate complex
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY
FDA UNII
CC9149U2QX
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY
MERCK INDEX
M10021
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY Merck Index
PUBCHEM
76968835
Created by admin on Fri Dec 16 18:58:47 UTC 2022 , Edited by admin on Fri Dec 16 18:58:47 UTC 2022
PRIMARY
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PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE
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ACTIVE MOIETY