U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
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Details

Stereochemistry ABSOLUTE
Molecular Formula 5C12H22O11.C6H11O7.2Fe.Na.3O
Molecular Weight 2089.308
Optical Activity UNSPECIFIED
Defined Stereocenters 49 / 49
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM FERRIC GLUCONATE COMPLEX

SMILES

[O--].[O--].[O--].[Na+].[Fe+3].[Fe+3].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@H]1O[C@@](CO)(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O.OC[C@H]3O[C@@](CO)(O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](O)[C@@H]3O.OC[C@H]5O[C@@](CO)(O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)[C@@H]5O.OC[C@H]7O[C@@](CO)(O[C@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@@H]7O.OC[C@H]9O[C@@](CO)(O[C@H]%10O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%10O)[C@@H](O)[C@@H]9O

InChI

InChIKey=MQBDAEHWGRMADS-XNHLMZCASA-M
InChI=1S/5C12H22O11.C6H12O7.2Fe.Na.3O/c5*13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12;7-1-2(8)3(9)4(10)5(11)6(12)13;;;;;;/h5*4-11,13-20H,1-3H2;2-5,7-11H,1H2,(H,12,13);;;;;;/q;;;;;;2*+3;+1;3*-2/p-1/t5*4-,5-,6-,7-,8+,9-,10+,11-,12+;2-,3-,4+,5-;;;;;;/m111111....../s1

HIDE SMILES / InChI

Molecular Formula C12H22O11
Molecular Weight 342.2965
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 9 / 9
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C6H8O7
Molecular Weight 192.1235
Charge -4
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Ferric Ammonium EDTA Solution is normally used as a photographic chemical for a bleaching agent in the process of colour washing. It is also used as a complexing, and oxidizing agent & as a fertilizer and catalyst. EDTA acid are colourless, water-soluble solid that are widely used to dissolve scale. The usefulness of these ammonium salts arise because of its role as a chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+.

Originator

Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

1998
Palliative
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

2014
PubMed

PubMed

TitleDatePubMed
[Effects of ferric fluoride compounds on dental enamel].
1954 Nov 15
The formation of ferritin from apoferritin. Kinetics and mechanism of iron uptake.
1972 Jan
The formation of ferritin from apoferritin. Catalytic action of apoferritin.
1973 Oct
The absorption of iron as supplements in infant cereal and infant formulas.
1975 May
Biological availability of iron supplements for rats, chicks and humans.
1976 Feb
Carcinogenicity studies on natural and man-made fibres with the intraperitoneal test in rats.
1989
Fabrication of FeF3 Nanoflowers on CNT branches and their application to high power lithium rechargeable batteries.
2010 Dec 7
Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions.
2011 Jun
Finnish wallpaper pigments in the 18th-19th century: presence of KFe3(CrO4)2(OH)6 and odd pigment mixtures.
2013 Apr
Microwave assisted convenient one-pot synthesis of coumarin derivatives via Pechmann condensation catalyzed by FeF3 under solvent-free conditions and antimicrobial activities of the products.
2014 Aug 26
FeF(3) catalyzed cascade C-C and C-N bond formation: synthesis of differentially substituted triheterocyclic benzothiazole functionalities under solvent-free condition.
2014 May
Heme Binding by Corynebacterium diphtheriae HmuT: Function and Heme Environment.
2015 Nov 3
Superior electrochemical performance of N-doped nanocrystalline FeF(3)/C with a single-step solid-state process.
2016 Oct 4
Phosphorus recovery from biogas slurry by ultrasound/H(2)O(2) digestion coupled with HFO/biochar adsorption process.
2017 Feb
Patents

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Bovine enamel was treated with 10 mM FeF3 (Ferric fluoride)
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:16:28 GMT 2025
Edited
by admin
on Mon Mar 31 18:16:28 GMT 2025
Record UNII
CC9149U2QX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERRIC NA GLUCONATE
VANDF  
Preferred Name English
SODIUM FERRIC GLUCONATE COMPLEX
MART.   MI   ORANGE BOOK   USAN  
USAN  
Official Name English
SODIUM FERRIC GLUCONATE
Common Name English
FERRLECIT
Brand Name English
SODIUM FERRIC GLUCONATE COMPLEX [MART.]
Common Name English
SODIUM FERRIC GLUCONATE COMPLEX [USAN]
Common Name English
Ferric sodium gluconate complex [WHO-DD]
Common Name English
IRON SODIUM GLUCONATE
Common Name English
SODIUM FERRIGLUCONATE
Common Name English
SODIUM FERRIC GLUCONATE COMPLEX [ORANGE BOOK]
Common Name English
OSMOFERRIN
Brand Name English
FERRIC SODIUM GLUCONATE COMPLEX
WHO-DD  
Common Name English
FERRIC NA GLUCONATE COMPLEX [VANDF]
Common Name English
FERRIC NA GLUCONATE [VANDF]
Common Name English
FERRIC SODIUM GLUCONATE
Common Name English
SODIUM FERRIC GLUCONATE COMPLEX [MI]
Common Name English
FERLIXIT
Brand Name English
FERRIC NA GLUCONATE COMPLEX
VANDF  
Common Name English
IRON (SODIUM FERRIC GLUCONATE COMPLEX IN SUCROSE INJECTION)
Common Name English
Classification Tree Code System Code
NDF-RT N0000177913
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
NDF-RT N0000006237
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
NDF-RT N0000006237
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
NDF-RT N0000006237
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
Code System Code Type Description
CAS
34089-81-1
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
NON-SPECIFIC STOICHIOMETRY
NCI_THESAURUS
C77274
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY
DRUG BANK
DB09517
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY
DAILYMED
CC9149U2QX
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY
SMS_ID
100000087402
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY
LACTMED
Sodium Ferric Gluconate Complex
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY
EVMPD
SUB13850MIG
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY
EVMPD
SUB20743
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY
EPA CompTox
DTXSID80187686
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY
ChEMBL
CHEMBL1201494
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY
RXCUI
261435
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY RxNorm
USAN
KK-97
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY
NCI_THESAURUS
C1505
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
CONCEPT Dietary Supplement
WIKIPEDIA
Sodium ferric gluconate complex
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY
FDA UNII
CC9149U2QX
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY
MERCK INDEX
m10021
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY Merck Index
PUBCHEM
76968835
Created by admin on Mon Mar 31 18:16:28 GMT 2025 , Edited by admin on Mon Mar 31 18:16:28 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE
Related Record Type Details
ACTIVE MOIETY