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Details

Stereochemistry ACHIRAL
Molecular Formula Fe.2O4S.12H2O.H4N
Molecular Weight 482.192
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERRIC AMMONIUM SULFATE DODECAHYDRATE

SMILES

[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[Fe+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O

InChI

InChIKey=LCPUDZUWZDSKMX-UHFFFAOYSA-K
InChI=1S/Fe.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3

HIDE SMILES / InChI
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula H3N
Molecular Weight 17.0305
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula H2O4S
Molecular Weight 98.078
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Sources: https://books.google.ru/books?id=vxtxWneRBN4C&pg=PA1103&#v=onepage&q&f=falsehttps://mistralhowto.wordpress.com/2012/03/12/what-is-pigment-yellow-42-and-what-is-it-used-for/ | http://sensientfoodcolors.com/en-us/confection/iron-oxides-approved-by-the-fda/ | https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=73.2250 | https://www.drugs.com/inactive/ferric-oxide-yellow-381.htmlhttp://www.mfc.co.jp/english/eng/product/sanferol/pdf/fls_gras_notice.pdfhttps://www.accessdata.fda.gov/drugsatfda_docs/nda/2014/205874Orig1s000PharmR.pdfhttps://cameochemicals.noaa.gov/chemical/3468 | https://www.ncbi.nlm.nih.gov/pubmed/2135524http://www.edta-chelate.com/ferric-ammonium-edta-liquid--1640836.htmlhttps://books.google.ru/books?id=3hLmyma2-MsC&pg=PA241&lpg=PA241&dq=FERRIC+AMMONIUM+CHLORIDE retrieved from A Consumer's Dictionary of Cosmetic Ingredients, 7th Edition: Complete Information About the Harmful and Desirable Ingredients Found in Cosmetics and Cosmeceuticals By Ruth Winterhttps://www.ncbi.nlm.nih.gov/pubmed/27995746 | http://onlinelibrary.wiley.com/doi/10.1002/047084289X.rn01568/abstract?userIsAuthenticated=false&deniedAccessCustomisedMessage=
Curator's Comment: description was created based on several sources, including http://www.mfc.co.jp/english/eng/product/sanferol/index.html

Ferric bromide, red-brown odorless compound, an oxidizing reagent, used as a catalyst for organic reactions, particularly in bromination of aromatic compounds.

Originator

Monsanto Chemicals
43
Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

1921
1447
Targets

Targets

Primary TargetPharmacologyConditionPotency
Activator
1404
Chelating Agent
143
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Basic research
Unknown

Approved Use

Unknown
Primary
Approved
8307
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Approved
8307
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

9.0935997E11
Curative
Approved
8307
RADIOGARDASE

Approved Use

Insoluble Prussian blue is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination.

Launch Date

1.06496642E12
Palliative
Approved
8307
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

1.40978881E12
PubMed

PubMed

TitleDatePubMed
The absorption of iron as supplements in infant cereal and infant formulas.
1975 May
Carcinogenicity studies on natural and man-made fibres with the intraperitoneal test in rats.
1989
Metal-mediated cyclization of aryl and benzyl glycidyl ethers: a complete scenario.
2008 Dec 17
Oxidative aromatic C-N bond formation: convenient synthesis of N-amino-3-nitrile-indoles via FeBr3-mediated intramolecular cyclization.
2011 May 21
Finnish wallpaper pigments in the 18th-19th century: presence of KFe3(CrO4)2(OH)6 and odd pigment mixtures.
2013 Apr
FeF(3) catalyzed cascade C-C and C-N bond formation: synthesis of differentially substituted triheterocyclic benzothiazole functionalities under solvent-free condition.
2014 May
Patents

Patents

20080188032
43
20090216060
43
6258758
43
US 5206265 A
43
US2385188
43
US4364871
43
US6881255
43
US6903235
43
US7198668
43

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
As a food supplement, ferric sodium pyrophosphate is administered orally.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 17 10:39:36 UTC 2022
Edited
by admin
on Sat Dec 17 10:39:36 UTC 2022
Record UNII
65390568Z5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERRIC AMMONIUM SULFATE DODECAHYDRATE
Common Name English
AMMONIUM FERRIC SULFATE DODECAHYDRATE [MI]
Common Name English
AMMONIUM FERRIC SULFATE DODECAHYDRATE
MI  
Common Name English
SULFURIC ACID, AMMONIUM IRON(3+) SALT (2:1:1), DODECAHYDRATE
Common Name English
AMMONIUM IRON(III) SULFATE DODECAHYDRATE
Systematic Name English
AMMONIUM IRON SULFATE ((NH4)FE(SO4)2) DODECAHYDRATE
Common Name English
AMMONIUM IRON(3+) DISULFATE DODECAHYDRATE
Systematic Name English
Code System Code Type Description
CAS
7783-83-7
Created by admin on Sat Dec 17 10:39:36 UTC 2022 , Edited by admin on Sat Dec 17 10:39:36 UTC 2022
PRIMARY
MESH
C049467
Created by admin on Sat Dec 17 10:39:36 UTC 2022 , Edited by admin on Sat Dec 17 10:39:36 UTC 2022
PRIMARY
PUBCHEM
197097
Created by admin on Sat Dec 17 10:39:36 UTC 2022 , Edited by admin on Sat Dec 17 10:39:36 UTC 2022
PRIMARY
EPA CompTox
DTXSID30228452
Created by admin on Sat Dec 17 10:39:36 UTC 2022 , Edited by admin on Sat Dec 17 10:39:36 UTC 2022
PRIMARY
FDA UNII
65390568Z5
Created by admin on Sat Dec 17 10:39:36 UTC 2022 , Edited by admin on Sat Dec 17 10:39:36 UTC 2022
PRIMARY
MERCK INDEX
M1785
Created by admin on Sat Dec 17 10:39:36 UTC 2022 , Edited by admin on Sat Dec 17 10:39:36 UTC 2022
PRIMARY Merck Index
Related Record Type Details
Structure of FERRIC CATION
PARENT -> SALT/SOLVATE
Structure of FERRIC AMMONIUM SULFATE ANHYDROUS
ANHYDROUS->SOLVATE
NIH
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