U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula Fe.2O4S.H4N
Molecular Weight 266.009
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERRIC AMMONIUM SULFATE ANHYDROUS

SMILES

[NH4+].[Fe+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O

InChI

InChIKey=XGGLLRJQCZROSE-UHFFFAOYSA-K
InChI=1S/Fe.H3N.2H2O4S/c;;2*1-5(2,3)4/h;1H3;2*(H2,1,2,3,4)/q+3;;;/p-3

HIDE SMILES / InChI

Molecular Formula HO4S
Molecular Weight 97.071
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula H3N
Molecular Weight 17.0305
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Originator

Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

9.0935997E11
Curative
RADIOGARDASE

Approved Use

Insoluble Prussian blue is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination.

Launch Date

1.06496642E12
Palliative
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

1.40978881E12
PubMed

PubMed

TitleDatePubMed
[Effects of ferric fluoride compounds on dental enamel].
1954 Nov 15
The formation of ferritin from apoferritin. Kinetics and mechanism of iron uptake.
1972 Jan
The formation of ferritin from apoferritin. Catalytic action of apoferritin.
1973 Oct
Contact dermatitis to yellow iron oxide.
1985 Aug
New phosphate binding agents: ferric compounds.
1999 Jun
Non-invasive and non-destructive micro-XRF and micro-Raman analysis of a decorative wallpaper from the beginning of the 19th century.
2007 Feb
Interaction of omapatrilat with FD&C Blue No. 2 lake during dissolution of modified release tablets.
2007 Jul 18
Metal-mediated cyclization of aryl and benzyl glycidyl ethers: a complete scenario.
2008 Dec 17
Fabrication of FeF3 Nanoflowers on CNT branches and their application to high power lithium rechargeable batteries.
2010 Dec 7
Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions.
2011 Jun
Finnish wallpaper pigments in the 18th-19th century: presence of KFe3(CrO4)2(OH)6 and odd pigment mixtures.
2013 Apr
Microwave assisted convenient one-pot synthesis of coumarin derivatives via Pechmann condensation catalyzed by FeF3 under solvent-free conditions and antimicrobial activities of the products.
2014 Aug 26
FeF(3) catalyzed cascade C-C and C-N bond formation: synthesis of differentially substituted triheterocyclic benzothiazole functionalities under solvent-free condition.
2014 May
Heme Binding by Corynebacterium diphtheriae HmuT: Function and Heme Environment.
2015 Nov 3
Mechanisms and origins of the switchable regioselectivity of FeBr3-catalyzed [1,2]-aryl and [1,2]-alkyl shifts of α-aryl aldehydes.
2016 Feb 28
Halide Influence on Molecular and Supramolecular Arrangements of Iron Complexes with a 3,5-Bis(2-Pyridyl)-1,2,4,6-Thiatriazine Ligand.
2016 Jun 6
Iron-Catalyzed Regioselective Transfer Hydrogenative Couplings of Unactivated Aldehydes with Simple Alkenes.
2016 May 17
Superior electrochemical performance of N-doped nanocrystalline FeF(3)/C with a single-step solid-state process.
2016 Oct 4
A Simplified Fe-Based PhotoATRP Using Only Monomers and Solvent.
2017 Jul
Patents

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
As a food supplement, ferric sodium pyrophosphate is administered orally.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 17 06:57:19 UTC 2022
Edited
by admin
on Sat Dec 17 06:57:19 UTC 2022
Record UNII
LUX2X1H1IC
Record Status Validated (UNII)
Record Version
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Name Type Language
FERRIC AMMONIUM SULFATE ANHYDROUS
Common Name English
AMMONIUM IRON SULFATE
Systematic Name English
AMMONIUM FERRIC SULFATE [MI]
Common Name English
AMMONIUM FERRIC SULFATE ANHYDROUS
Common Name English
FERRIC AMMONIUM DISULFATE
Common Name English
MONOAMMONIUM FERRIC DISULFATE
Common Name English
FERRIAMMONIUM SULFATE
Common Name English
IRON AMMONIUM DISULFATE
Systematic Name English
AMMONIUM IRON BIS(SULFATE)
Systematic Name English
AMMONIUM IRON SULFATE (NH4FE(SO4)2)
Common Name English
AMMONIUM IRON(III) SULFATE
Systematic Name English
NSC-27280
Code English
AMMONIUM FERRIC SULFATE
MI  
Common Name English
AMMONIUM IRON DISULFATE
Systematic Name English
AMMONIUM FERRIC SULFATE (NH4FE(SO4)2)
Common Name English
AMMONIUM FERRIC ALUM
Common Name English
FERRIC AMMONIUM ALUM
Common Name English
SULFURIC ACID, AMMONIUM IRON(3+) SALT (2:1:1)
Common Name English
FERRIC AMMONIUM SULFATE
WHO-DD  
Common Name English
Ferric ammonium sulfate [WHO-DD]
Common Name English
Code System Code Type Description
ECHA (EC/EINECS)
233-382-4
Created by admin on Sat Dec 17 06:57:20 UTC 2022 , Edited by admin on Sat Dec 17 06:57:20 UTC 2022
PRIMARY
WIKIPEDIA
AMMONIUM IRON(III) SULFATE
Created by admin on Sat Dec 17 06:57:20 UTC 2022 , Edited by admin on Sat Dec 17 06:57:20 UTC 2022
PRIMARY
EVMPD
SUB13835MIG
Created by admin on Sat Dec 17 06:57:20 UTC 2022 , Edited by admin on Sat Dec 17 06:57:20 UTC 2022
PRIMARY
NSC
27280
Created by admin on Sat Dec 17 06:57:20 UTC 2022 , Edited by admin on Sat Dec 17 06:57:20 UTC 2022
PRIMARY
PUBCHEM
61485
Created by admin on Sat Dec 17 06:57:20 UTC 2022 , Edited by admin on Sat Dec 17 06:57:20 UTC 2022
PRIMARY
MERCK INDEX
M1785
Created by admin on Sat Dec 17 06:57:20 UTC 2022 , Edited by admin on Sat Dec 17 06:57:20 UTC 2022
PRIMARY Merck Index
CAS
10138-04-2
Created by admin on Sat Dec 17 06:57:20 UTC 2022 , Edited by admin on Sat Dec 17 06:57:20 UTC 2022
PRIMARY
CHEBI
76243
Created by admin on Sat Dec 17 06:57:20 UTC 2022 , Edited by admin on Sat Dec 17 06:57:20 UTC 2022
PRIMARY
FDA UNII
LUX2X1H1IC
Created by admin on Sat Dec 17 06:57:20 UTC 2022 , Edited by admin on Sat Dec 17 06:57:20 UTC 2022
PRIMARY
EPA CompTox
DTXSID8051417
Created by admin on Sat Dec 17 06:57:20 UTC 2022 , Edited by admin on Sat Dec 17 06:57:20 UTC 2022
PRIMARY
Related Record Type Details
SOLVATE->ANHYDROUS
PARENT -> SALT/SOLVATE