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Details

Stereochemistry ACHIRAL
Molecular Formula Fe.2O4S.H4N
Molecular Weight 266.009
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERRIC AMMONIUM SULFATE ANHYDROUS

SMILES

[NH4+].[Fe+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O

InChI

InChIKey=XGGLLRJQCZROSE-UHFFFAOYSA-K
InChI=1S/Fe.H3N.2H2O4S/c;;2*1-5(2,3)4/h;1H3;2*(H2,1,2,3,4)/q+3;;;/p-3

HIDE SMILES / InChI
Molecular Formula H3N
Molecular Weight 17.0305
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula HO4S
Molecular Weight 97.071
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including http://www.mfc.co.jp/english/eng/product/sanferol/index.html

Ferric Ammonium EDTA Solution is normally used as a photographic chemical for a bleaching agent in the process of colour washing. It is also used as a complexing, and oxidizing agent & as a fertilizer and catalyst. EDTA acid are colourless, water-soluble solid that are widely used to dissolve scale. The usefulness of these ammonium salts arise because of its role as a chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+.

Originator

Monsanto Chemicals
40
Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

1921
1468
Targets

Targets

Primary TargetPharmacologyConditionPotency
Activator
1447
Chelating Agent
139
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Basic research
Unknown

Approved Use

Unknown
Primary
Approved
8583
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Approved
8583
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

1998
Palliative
Approved
8583
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

2014
PubMed

PubMed

TitleDatePubMed
[Effects of ferric fluoride compounds on dental enamel].
1954 Nov 15
The formation of ferritin from apoferritin. Kinetics and mechanism of iron uptake.
1972 Jan
The formation of ferritin from apoferritin. Catalytic action of apoferritin.
1973 Oct
The absorption of iron as supplements in infant cereal and infant formulas.
1975 May
Biological availability of iron supplements for rats, chicks and humans.
1976 Feb
Contact dermatitis to yellow iron oxide.
1985 Aug
Carcinogenicity studies on natural and man-made fibres with the intraperitoneal test in rats.
1989
Effect of physical exercise and vitamin C on absorption of ferric sodium citrate.
1996 Dec
New phosphate binding agents: ferric compounds.
1999 Jun
Non-invasive and non-destructive micro-XRF and micro-Raman analysis of a decorative wallpaper from the beginning of the 19th century.
2007 Feb
Interaction of omapatrilat with FD&C Blue No. 2 lake during dissolution of modified release tablets.
2007 Jul 18
Fabrication of FeF3 Nanoflowers on CNT branches and their application to high power lithium rechargeable batteries.
2010 Dec 7
Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions.
2011 Jun
Finnish wallpaper pigments in the 18th-19th century: presence of KFe3(CrO4)2(OH)6 and odd pigment mixtures.
2013 Apr
Microwave assisted convenient one-pot synthesis of coumarin derivatives via Pechmann condensation catalyzed by FeF3 under solvent-free conditions and antimicrobial activities of the products.
2014 Aug 26
FeF(3) catalyzed cascade C-C and C-N bond formation: synthesis of differentially substituted triheterocyclic benzothiazole functionalities under solvent-free condition.
2014 May
Heme Binding by Corynebacterium diphtheriae HmuT: Function and Heme Environment.
2015 Nov 3
Superior electrochemical performance of N-doped nanocrystalline FeF(3)/C with a single-step solid-state process.
2016 Oct 4
Phosphorus recovery from biogas slurry by ultrasound/H(2)O(2) digestion coupled with HFO/biochar adsorption process.
2017 Feb
Patents

Patents

20090216060
40
6258758
40
US 5206265 A
40
US2385188
40
US4364871
40
US6881255
40
US6903235
40
US7198668
40

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Bovine enamel was treated with 10 mM FeF3 (Ferric fluoride)
Substance Class Chemical
Created
by admin
on Mon Mar 31 20:21:15 GMT 2025
Edited
by admin
on Mon Mar 31 20:21:15 GMT 2025
Record UNII
LUX2X1H1IC
Record Status Validated (UNII)
Record Version
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Name Type Language
FERRIC AMMONIUM SULFATE ANHYDROUS
Common Name English
FERRIC AMMONIUM SULFATE
WHO-DD  
Preferred Name English
AMMONIUM IRON SULFATE
Systematic Name English
AMMONIUM FERRIC SULFATE [MI]
Common Name English
AMMONIUM FERRIC SULFATE ANHYDROUS
Common Name English
FERRIC AMMONIUM DISULFATE
Common Name English
MONOAMMONIUM FERRIC DISULFATE
Common Name English
FERRIAMMONIUM SULFATE
Common Name English
IRON AMMONIUM DISULFATE
Systematic Name English
AMMONIUM IRON BIS(SULFATE)
Systematic Name English
AMMONIUM IRON SULFATE (NH4FE(SO4)2)
Common Name English
AMMONIUM IRON(III) SULFATE
Systematic Name English
NSC-27280
Code English
AMMONIUM FERRIC SULFATE
MI  
Common Name English
AMMONIUM IRON DISULFATE
Systematic Name English
AMMONIUM FERRIC SULFATE (NH4FE(SO4)2)
Common Name English
AMMONIUM FERRIC ALUM
Common Name English
FERRIC AMMONIUM ALUM
Common Name English
SULFURIC ACID, AMMONIUM IRON(3+) SALT (2:1:1)
Common Name English
Ferric ammonium sulfate [WHO-DD]
Common Name English
Code System Code Type Description
ECHA (EC/EINECS)
233-382-4
Created by admin on Mon Mar 31 20:21:15 GMT 2025 , Edited by admin on Mon Mar 31 20:21:15 GMT 2025
PRIMARY
WIKIPEDIA
AMMONIUM IRON(III) SULFATE
Created by admin on Mon Mar 31 20:21:15 GMT 2025 , Edited by admin on Mon Mar 31 20:21:15 GMT 2025
PRIMARY
EVMPD
SUB13835MIG
Created by admin on Mon Mar 31 20:21:15 GMT 2025 , Edited by admin on Mon Mar 31 20:21:15 GMT 2025
PRIMARY
SMS_ID
100000092823
Created by admin on Mon Mar 31 20:21:15 GMT 2025 , Edited by admin on Mon Mar 31 20:21:15 GMT 2025
PRIMARY
NSC
27280
Created by admin on Mon Mar 31 20:21:15 GMT 2025 , Edited by admin on Mon Mar 31 20:21:15 GMT 2025
PRIMARY
PUBCHEM
61485
Created by admin on Mon Mar 31 20:21:15 GMT 2025 , Edited by admin on Mon Mar 31 20:21:15 GMT 2025
PRIMARY
MERCK INDEX
m1785
Created by admin on Mon Mar 31 20:21:15 GMT 2025 , Edited by admin on Mon Mar 31 20:21:15 GMT 2025
PRIMARY Merck Index
CAS
10138-04-2
Created by admin on Mon Mar 31 20:21:15 GMT 2025 , Edited by admin on Mon Mar 31 20:21:15 GMT 2025
PRIMARY
CHEBI
76243
Created by admin on Mon Mar 31 20:21:15 GMT 2025 , Edited by admin on Mon Mar 31 20:21:15 GMT 2025
PRIMARY
FDA UNII
LUX2X1H1IC
Created by admin on Mon Mar 31 20:21:15 GMT 2025 , Edited by admin on Mon Mar 31 20:21:15 GMT 2025
PRIMARY
EPA CompTox
DTXSID8051417
Created by admin on Mon Mar 31 20:21:15 GMT 2025 , Edited by admin on Mon Mar 31 20:21:15 GMT 2025
PRIMARY
Related Record Type Details
Structure of FERRIC AMMONIUM SULFATE DODECAHYDRATE
SOLVATE->ANHYDROUS
Structure of FERRIC CATION
PARENT -> SALT/SOLVATE
NIH
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