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Details

Stereochemistry ACHIRAL
Molecular Formula 3C18H33O2.Fe
Molecular Weight 900.2074
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 3
Charge 0

SHOW SMILES / InChI
Structure of FERRIC OLEATE

SMILES

CCCCCCCC/C(/[H])=C(/[H])\CCCCCCCC(=O)[O-].CCCCCCCC/C(/[H])=C(/[H])\CCCCCCCC(=O)[O-].CCCCCCCC/C(/[H])=C(/[H])\CCCCCCCC(=O)[O-].[Fe+3]

InChI

InChIKey=HOIQWTMREPWSJY-GNOQXXQHSA-K
InChI=1S/3C18H34O2.Fe/c3*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h3*9-10H,2-8,11-17H2,1H3,(H,19,20);/q;;;+3/p-3/b3*10-9-;

HIDE SMILES / InChI

Molecular Formula Fe
Molecular Weight 55.8451
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C18H33O2
Molecular Weight 281.4541
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
0.5 nM [IC50]
5.0 nM [IC50]
6.0 nM [IC50]
920.0 nM [IC50]
0.5 nM [IC50]
0.5 nM [IC50]
6.0 nM [IC50]
13.0 nM [IC50]
50.0 nM [IC50]
0.5 nM [IC50]
0.9 nM [IC50]
1.2 nM [IC50]
Target ID: Q92993|||Q9BWK7
Gene ID: 10524.0
Gene Symbol: KAT5
Target Organism: Homo sapiens (Human)
Conditions
PubMed

PubMed

TitleDatePubMed
DBM1285 suppresses tumor necrosis factor alpha production by blocking p38 mitogen-activated protein kinase/mitogen-activated protein kinase-activated protein kinase 2 signaling pathway.
2010 Aug
Reactivity of endo-3-bromocamphor with sulfur-centered nucleophiles by an electron transfer mechanism. Electrophilic behaviour of the 3-camphoryl radical.
2011 Apr 21
Characterization of the cellular action of the MSK inhibitor SB-747651A.
2012 Jan 1
Selective inhibition of BTK prevents murine lupus and antibody-mediated glomerulonephritis.
2013 Nov 1
Targeting spleen tyrosine kinase-Bruton's tyrosine kinase axis for immunologically mediated glomerulonephritis.
2014
A low cost synthesis method for functionalised iron oxide nanoparticles for magnetic hyperthermia from readily available materials.
2014
Crosstalk between epigenetic readers regulates the MOZ/MORF HAT complexes.
2014 Feb
PKA-dependent phosphorylation of LIMK1 and Cofilin is essential for mouse sperm acrosomal exocytosis.
2015 Sep 15
Bromodomain inhibitors and cancer therapy: From structures to applications.
2017 May 4
Patents

Sample Use Guides

NZBxW_F1 mice were treated with 3, 10, or 30 mg/kg PF- 06250112 starting at 26 wk of age, at which time all animals have elevated anti-dsDNA titers and severe proteinuria begins to develop. Treatment with PF-06250112 was continued for 12 wk.
Route of Administration: Oral
Treatment with PF-06250112 profoundly suppressed the production of inositol monophosphate in Ramos cells, a human B cell line, with an IC50 of 12 nM. Purified primary human B cells stimulated through the BCR undergo robust proliferation in vitro, and treatment with the PF-06250112 significantly inhibited this response with an IC50 of 2.5 nM.
Substance Class Chemical
Created
by admin
on Fri Jun 25 21:59:26 UTC 2021
Edited
by admin
on Fri Jun 25 21:59:26 UTC 2021
Record UNII
C1NE1661VN
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERRIC OLEATE
Common Name English
9-OCTADECENOIC ACID (9Z)-, IRON(3+) SALT (3:1)
Common Name English
IRON TRIOLEATE
Common Name English
IRON OLEATE, (FE 3+)-
Common Name English
NSC-112238
Code English
OLEIC ACID, IRON(3+) SALT
Common Name English
9-OCTADECENOIC ACID (Z)-, IRON(3+) SALT
Common Name English
9-OCTADECENOIC ACID (9Z)-, IRON(3+) SALT
Common Name English
IRON(III) OLEATE
Common Name English
Code System Code Type Description
FDA UNII
C1NE1661VN
Created by admin on Fri Jun 25 21:59:26 UTC 2021 , Edited by admin on Fri Jun 25 21:59:26 UTC 2021
PRIMARY
CAS
1120-45-2
Created by admin on Fri Jun 25 21:59:26 UTC 2021 , Edited by admin on Fri Jun 25 21:59:26 UTC 2021
PRIMARY
PUBCHEM
14009126
Created by admin on Fri Jun 25 21:59:26 UTC 2021 , Edited by admin on Fri Jun 25 21:59:26 UTC 2021
PRIMARY
ECHA (EC/EINECS)
214-309-5
Created by admin on Fri Jun 25 21:59:26 UTC 2021 , Edited by admin on Fri Jun 25 21:59:26 UTC 2021
PRIMARY
CAS
23335-74-2
Created by admin on Fri Jun 25 21:59:26 UTC 2021 , Edited by admin on Fri Jun 25 21:59:26 UTC 2021
NON-SPECIFIC STOICHIOMETRY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE