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Details

Stereochemistry ACHIRAL
Molecular Formula C6H4O7.C5H14NO.Fe
Molecular Weight 348.1081
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERROCHOLINATE ANHYDROUS

SMILES

C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])[O-].C[N+](C)(C)CCO.[Fe+3]

InChI

InChIKey=YJBFEDKRBVBHSN-UHFFFAOYSA-K
InChI=1S/C6H7O7.C5H14NO.Fe/c7-3(8)1-6(13,5(11)12)2-4(9)10;1-6(2,3)4-5-7;/h1-2H2,(H,7,8)(H,9,10)(H,11,12);7H,4-5H2,1-3H3;/q-1;+1;+3/p-3

HIDE SMILES / InChI

Molecular Formula C5H13NO
Molecular Weight 103.163
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Fe
Molecular Weight 55.8451
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C6H5O7
Molecular Weight 189.1
Charge -3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment:: description was created based on several sources, including: http://www.druginfosys.com/drug.aspx?drugcode=1316&type=1 | http://www.vademecum.es/medicamento-podertonic+adultos_3181

Ferrocholinate is a chelate prepared by reacting equal quantities of freshly precipitated ferric chloride with choline dihydrogen citrate. Ferrocholinate is used as a source of iron in iron deficiency anemia. Ferrocholinate absorption is increased by simultaneous administration of ascorbic acid. Absorption reduced by antacids, cholestyramine or proton pump inhibitors (omeprazole, pantoprazole, lansoprazole). The following adverse effects may occur: occasionally, gastrointestinal disorders (stomach pain, nausea, constipation or diarrhea) may appear, which usually disappear quickly after the dose is reduced or, if necessary, after treatment discontinuation. Darkness of stool: it is frequently observed during treatment and is safe for the patient. Allergic reactions may occur, also.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
FERROLIP

Approved Use

Ferrocholinate is primarily indicated in conditions like iron deficiency anaemia.

Launch Date

-2.86934401E11
Primary
FERROLIP

Approved Use

Treatment of iron deficiency states and iron deficiency anemia in adults and children, for deficient iron absorption, chronic bleeding or in situations where there is an increase of iron demands such as pregnancy or breastfeeding.

Launch Date

-2.86934401E11
Primary
FERROLIP

Approved Use

Treatment of iron deficiency states and iron deficiency anemia in adults and children, for deficient iron absorption, chronic bleeding or in situations where there is an increase of iron demands such as pregnancy or breastfeeding.

Launch Date

-2.86934401E11
PubMed

PubMed

TitleDatePubMed
Pediatric use of ferrocholinate.
1962 Jul
Patents

Sample Use Guides

In Vivo Use Guide
Curator's Comment:: http://www.ndrugs.com/?s=podertonic%20ni%C3%B1os | https://clicks.co.za/chela-fer_iron-supplement-30-tablets/p/44856 | https://www.aemps.gob.es/cima/pdfs/es/ft/54556/54556_ft.pdf
1 tablet (100 mg) daily Adults daily dose is equivalent to 112.6 mg Fe3. Take this medication preferably a few hours before meals. Duration of treatment depends on nature and severity of iron deficiency.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Jun 25 23:29:01 UTC 2021
Edited
by admin
on Fri Jun 25 23:29:01 UTC 2021
Record UNII
0W21KB56NS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERROCHOLINATE ANHYDROUS
Common Name English
ETHANAMINIUM, 2-HYDROXY-N,N,N-TRIMETHYL-, (OC-6-44)-(2-(HYDROXY-.KAPPA.O)-1,2,3-PROPANETRICARBOXYLATO(4-)-.KAPPA.O1,.KAPPA.O2)FERRATE(1-) (1:1)
Common Name English
Code System Code Type Description
PUBCHEM
76966607
Created by admin on Fri Jun 25 23:29:01 UTC 2021 , Edited by admin on Fri Jun 25 23:29:01 UTC 2021
PRIMARY
FDA UNII
0W21KB56NS
Created by admin on Fri Jun 25 23:29:01 UTC 2021 , Edited by admin on Fri Jun 25 23:29:01 UTC 2021
PRIMARY
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