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Details

Stereochemistry ABSOLUTE
Molecular Formula C12H22O11.Fe.3HO
Molecular Weight 449.164
Optical Activity UNSPECIFIED
Defined Stereocenters 9 / 9
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of IRON POLYMALTOSE

SMILES

[OH-].[OH-].[OH-].[Fe+3].OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

InChIKey=PKMVWNYIYVZXIQ-MPAYLTKRSA-K
InChI=1S/C12H22O11.Fe.3H2O/c13-1-4(15)7(17)8(18)5(16)3-22-12-11(21)10(20)9(19)6(2-14)23-12;;;;/h1,4-12,14-21H,2-3H2;;3*1H2/q;+3;;;/p-3/t4-,5+,6+,7+,8+,9+,10-,11+,12-;;;;/m0..../s1

HIDE SMILES / InChI

Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C12H22O11
Molecular Weight 342.2965
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 9 / 9
E/Z Centers 0
Optical Activity UNSPECIFIED

Originator

Curator's Comment: The relation between phosphate level and ferric citrate consumption was first discovered in 1940s.

Approval Year

TargetsConditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown

Approved Use

Unknown
Primary
SANFEROL

Approved Use

It has also been reported that SFC preparation improved iron deficiency in a pregnant woman with iron deficiency anemia whose hemoglobin level had not increased after administration of other iron preparations such as ferrous fumarate. A dairy supplemental dose of SFC improved iron deficiency in young women with iron deficiency.
Inactive ingredient
Oxycontin

Approved Use

OxyContin is used in the treatment of chronic pain; pain and belongs to the drug class narcotic analgesics.

Launch Date

9.0935997E11
Curative
RADIOGARDASE

Approved Use

Insoluble Prussian blue is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination.

Launch Date

1.06496642E12
Palliative
AURYXIA

Approved Use

Ferric Citrate is a phosphate binder indicated for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis.

Launch Date

1.40978881E12
PubMed

PubMed

TitleDatePubMed
[Effects of ferric fluoride compounds on dental enamel].
1954 Nov 15
The formation of ferritin from apoferritin. Kinetics and mechanism of iron uptake.
1972 Jan
The formation of ferritin from apoferritin. Catalytic action of apoferritin.
1973 Oct
Contact dermatitis to yellow iron oxide.
1985 Aug
Effect of physical exercise and vitamin C on absorption of ferric sodium citrate.
1996 Dec
New phosphate binding agents: ferric compounds.
1999 Jun
Non-invasive and non-destructive micro-XRF and micro-Raman analysis of a decorative wallpaper from the beginning of the 19th century.
2007 Feb
Interaction of omapatrilat with FD&C Blue No. 2 lake during dissolution of modified release tablets.
2007 Jul 18
Metal-mediated cyclization of aryl and benzyl glycidyl ethers: a complete scenario.
2008 Dec 17
Fabrication of FeF3 Nanoflowers on CNT branches and their application to high power lithium rechargeable batteries.
2010 Dec 7
Thermal behavior study and decomposition kinetics of amiodarone hydrochloride under isothermal conditions.
2011 Jun
Oxidative aromatic C-N bond formation: convenient synthesis of N-amino-3-nitrile-indoles via FeBr3-mediated intramolecular cyclization.
2011 May 21
Finnish wallpaper pigments in the 18th-19th century: presence of KFe3(CrO4)2(OH)6 and odd pigment mixtures.
2013 Apr
Microwave assisted convenient one-pot synthesis of coumarin derivatives via Pechmann condensation catalyzed by FeF3 under solvent-free conditions and antimicrobial activities of the products.
2014 Aug 26
Heme Binding by Corynebacterium diphtheriae HmuT: Function and Heme Environment.
2015 Nov 3
Mechanisms and origins of the switchable regioselectivity of FeBr3-catalyzed [1,2]-aryl and [1,2]-alkyl shifts of α-aryl aldehydes.
2016 Feb 28
Halide Influence on Molecular and Supramolecular Arrangements of Iron Complexes with a 3,5-Bis(2-Pyridyl)-1,2,4,6-Thiatriazine Ligand.
2016 Jun 6
Iron-Catalyzed Regioselective Transfer Hydrogenative Couplings of Unactivated Aldehydes with Simple Alkenes.
2016 May 17
Superior electrochemical performance of N-doped nanocrystalline FeF(3)/C with a single-step solid-state process.
2016 Oct 4
Phosphorus recovery from biogas slurry by ultrasound/H(2)O(2) digestion coupled with HFO/biochar adsorption process.
2017 Feb
A Simplified Fe-Based PhotoATRP Using Only Monomers and Solvent.
2017 Jul
Patents

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Iron oxides black, red and yellow are intended to be used as colourants in feedingstuffs for all animal species without dose or age restriction. The applicant recommends 500–1,200 mg/kg of the additives in complete (and complementary) feedingstuffs as standard dose. http://onlinelibrary.wiley.com/doi/10.2903/j.efsa.2016.4482/full
As a food supplement, ferric sodium pyrophosphate is administered orally.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 17 09:59:18 UTC 2022
Edited
by admin
on Sat Dec 17 09:59:18 UTC 2022
Record UNII
UM5219H89V
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IRON POLYMALTOSE
Common Name English
FERROMALTOSE
Common Name English
TEFERROL
Brand Name English
Ferric hydroxide polymaltose complex [WHO-DD]
Common Name English
AMYLOFER
Brand Name English
FERRIC HYDROXIDE POLYMALTOSE COMPLEX
WHO-DD  
Common Name English
IRON(III)-HYDROXIDE POLYMALTOSE COMPLEX
Common Name English
FERRIPEL 3
Brand Name English
MALTOFER
Brand Name English
FERRUMMATE
Brand Name English
Classification Tree Code System Code
WHO-ATC B03AB05
Created by admin on Sat Dec 17 09:59:19 UTC 2022 , Edited by admin on Sat Dec 17 09:59:19 UTC 2022
Code System Code Type Description
DAILYMED
UM5219H89V
Created by admin on Sat Dec 17 09:59:19 UTC 2022 , Edited by admin on Sat Dec 17 09:59:19 UTC 2022
PRIMARY
EVMPD
SUB13845MIG
Created by admin on Sat Dec 17 09:59:19 UTC 2022 , Edited by admin on Sat Dec 17 09:59:19 UTC 2022
PRIMARY
PUBCHEM
76960246
Created by admin on Sat Dec 17 09:59:19 UTC 2022 , Edited by admin on Sat Dec 17 09:59:19 UTC 2022
PRIMARY
CAS
53858-86-9
Created by admin on Sat Dec 17 09:59:19 UTC 2022 , Edited by admin on Sat Dec 17 09:59:19 UTC 2022
PRIMARY
RXCUI
37744
Created by admin on Sat Dec 17 09:59:19 UTC 2022 , Edited by admin on Sat Dec 17 09:59:19 UTC 2022
PRIMARY RxNorm
FDA UNII
UM5219H89V
Created by admin on Sat Dec 17 09:59:19 UTC 2022 , Edited by admin on Sat Dec 17 09:59:19 UTC 2022
PRIMARY
EPA CompTox
DTXSID101027608
Created by admin on Sat Dec 17 09:59:19 UTC 2022 , Edited by admin on Sat Dec 17 09:59:19 UTC 2022
PRIMARY
MESH
C013276
Created by admin on Sat Dec 17 09:59:19 UTC 2022 , Edited by admin on Sat Dec 17 09:59:19 UTC 2022
PRIMARY
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