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Details

Stereochemistry ACHIRAL
Molecular Formula 3CNS.Fe
Molecular Weight 230.092
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERRIC THIOCYANATE

SMILES

[Fe+3].[S-]C#N.[S-]C#N.[S-]C#N

InChI

InChIKey=SUBFIBLJQMMKBK-UHFFFAOYSA-K
InChI=1S/3CHNS.Fe/c3*2-1-3;/h3*3H;/q;;;+3/p-3

HIDE SMILES / InChI

Molecular Formula Fe
Molecular Weight 55.845
Charge 3
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula CHNS
Molecular Weight 59.09
Charge 0
Count
MOL RATIO 3 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Ferric thiocyanate is a complex of Fe3+ with [SCN]- ions. Solution of ferric thiocyanate has a blood red color, and its formation is used to detect Fe3+ ions. Oxidation of ferrous to ferric ion and subsequent complexation of the latter by thiocyanate is known as ferric thiocyanate assay and is used for determination of presence of various oxidizers, such as lipid hydroperoxides, and evaluation of effects of antioxidants.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Ammonium thiocyanate (7.5 g) was dissolved in 25 ml distilled deionized water (thiocyanate solution). Barium chloride dihydrate (0.2 g) was dissolved in 25 ml of 0.4 N HCl (solution A). Ferrous sulfate heptahydrate (0.1 g) was dissolved in 10 ml distilled deionized water (solution B). Six milliliters of solution A was mixed with 6 ml of solution B by vortexing for 1 min, followed by centrifugation for 3 min. The clear solution of Fe(II) chloride was used immediately after preparation. Cumene hydroperoxide was dissolved in nonpolar solvent prior to mixing with methanol. To 10 ml of the nonpolar solvent/methanol (2:1) mixture, 50 ml of ammonium thiocyanate solution was added and vortexed for 2–4 s. Then 50 ml of iron(II) chloride solution was added and vortexed for 2–4 s. After a 20-min incubation period at room temperature, the absorbance was determined at 500 nm.
Substance Class Chemical
Record UNII
46CC1IS9BT
Record Status Validated (UNII)
Record Version