U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Fri Jun 25 20:34:19 UTC 2021
Edited
by admin
on Fri Jun 25 20:34:19 UTC 2021
Protein Sub Type
Sequence Type COMPLETE
Record UNII
NJ1Q2Q7LO5
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CANNABINOID RECEPTOR 1
Common Name English
CANN6
Common Name English
CB1 RECEPTOR
Common Name English
CB1
Common Name English
CNR
Common Name English
CB-1`
Common Name English
CB-R
Common Name English
Code System Code Type Description
UNIPROT
P21554
Created by admin on Fri Jun 25 20:34:19 UTC 2021 , Edited by admin on Fri Jun 25 20:34:19 UTC 2021
PRIMARY
PHAROS
P21554
Created by admin on Fri Jun 25 20:34:19 UTC 2021 , Edited by admin on Fri Jun 25 20:34:19 UTC 2021
PRIMARY
FDA UNII
NJ1Q2Q7LO5
Created by admin on Fri Jun 25 20:34:19 UTC 2021 , Edited by admin on Fri Jun 25 20:34:19 UTC 2021
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_77
N 1_83
N 1_112
Related Record Type Details
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
Ki
AGONIST -> TARGET
EC50
AGONIST -> TARGET
AGONIST -> TARGET
EC50
INHIBITOR -> TARGET
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
Ki
AGONIST -> TARGET
EC50
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
Ki
AGONIST -> TARGET
Ki
AGONIST -> TARGET
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
Ki
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
AGONIST -> TARGET
EC50
AGONIST -> TARGET
EC50
AGONIST -> TARGET
Ki
AGONIST -> TARGET
ACTIVATOR -> TARGET
AGONIST -> TARGET
RADIOLIGAND->TARGET
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
EC50
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
EC50
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
EC50
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
EC50
AGONIST -> TARGET
EC50
AGONIST -> TARGET
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
INHIBITOR -> TARGET
Rimonabant was the first CB1r antagonist to be approved for the treatment of obesity in Europe (Van Gaal et al., 2005; Henness et al., 2006). It was withdrawn from the market in 2008 because it was found to cause a significant drug-related risk of serious psychiatric disorders including anxiety and depression (Christensen et al., 2007).
Ki
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
INVERSE AGONIST->TARGET
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
EC50
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
INVERSE AGONIST->TARGET
AGONIST -> TARGET
EC50
AGONIST -> TARGET
A potent agonist
AGONIST -> TARGET
EC50
AGONIST -> TARGET
EC50
AGONIST -> TARGET
EC50
AGONIST -> TARGET
EC50
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
INHIBITOR -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
5F-CUMYL-PEGACLONE acts as a potent full agonist of the CB1 receptor.
AGONIST -> TARGET
Ki
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
ASSUMED ACTIVITY FROM ANALOGS
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
Mouse AtT-20 neuroblastoma cells stably transfected with human CB1
EC50
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL