Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C27H27Cl2N5O3S |
| Molecular Weight | 572.506 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)[C@H](N\C(=N/S(=O)(=O)C1=CC=C(Cl)C=C1)N2C[C@@H](C(=N2)C3=CC=C(Cl)C=C3)C4=CC=CC=C4)C(N)=O
InChI
InChIKey=GTCSIQFTNPTSLO-RPWUZVMVSA-N
InChI=1S/C27H27Cl2N5O3S/c1-17(2)24(26(30)35)31-27(33-38(36,37)22-14-12-21(29)13-15-22)34-16-23(18-6-4-3-5-7-18)25(32-34)19-8-10-20(28)11-9-19/h3-15,17,23-24H,16H2,1-2H3,(H2,30,35)(H,31,33)/t23-,24+/m1/s1
| Molecular Formula | C27H27Cl2N5O3S |
| Molecular Weight | 572.506 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 1 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Amplitude-selective filtering for remote-PPG. | 2017 Mar 1 |
|
| Cannabinoid-1 Receptor Antagonism Improves Glycemic Control and Increases Energy Expenditure Through Sirtuin-1/Mechanistic Target of Rapamycin Complex 2 and 5'Adenosine Monophosphate-Activated Protein Kinase Signaling. | 2019 Apr |
|
| Preclinical toxicity evaluation of JD5037, a peripherally restricted CB(1) receptor inverse agonist, in rats and dogs for treatment of nonalcoholic steatohepatitis. | 2019 Dec |
|
| Dual inhibition of cannabinoid CB(1) receptor and inducible NOS attenuates obesity-induced chronic kidney disease. | 2020 Jan |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sun Dec 18 13:58:19 UTC 2022
by
admin
on
Sun Dec 18 13:58:19 UTC 2022
|
| Record UNII |
ENZ75DG2Z6
|
| Record Status |
Validated (UNII)
|
| Record Version |
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-
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ENZ75DG2Z6
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1392116-14-1
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admin on Sun Dec 18 13:58:19 UTC 2022 , Edited by admin on Sun Dec 18 13:58:19 UTC 2022
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66553204
Created by
admin on Sun Dec 18 13:58:19 UTC 2022 , Edited by admin on Sun Dec 18 13:58:19 UTC 2022
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DTXSID301030409
Created by
admin on Sun Dec 18 13:58:19 UTC 2022 , Edited by admin on Sun Dec 18 13:58:19 UTC 2022
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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TARGET->INVERSE AGONIST | |||
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METABOLIC ENZYME -> INHIBITOR |
at 10 ?M 80% inhibition
IC50
|
