Details
Stereochemistry | ACHIRAL |
Molecular Formula | C24H23NO |
Molecular Weight | 341.4455 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCN1C=C(C(=O)C2=CC=CC3=C2C=CC=C3)C4=C1C=CC=C4
InChI
InChIKey=JDNLPKCAXICMBW-UHFFFAOYSA-N
InChI=1S/C24H23NO/c1-2-3-8-16-25-17-22(20-13-6-7-15-23(20)25)24(26)21-14-9-11-18-10-4-5-12-19(18)21/h4-7,9-15,17H,2-3,8,16H2,1H3
Molecular Formula | C24H23NO |
Molecular Weight | 341.4455 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
DescriptionCurator's Comment: description was created based on several sources, including:
https://psychonautwiki.org/wiki/JWH-018 | https://en.wikipedia.org/wiki/JWH-018
Curator's Comment: description was created based on several sources, including:
https://psychonautwiki.org/wiki/JWH-018 | https://en.wikipedia.org/wiki/JWH-018
JWH-018 is a full agonist synthetic cannabinoid with a high binding affinity to CB1 and CB2 cannabinoid receptors. JWH-018 has not been used in therapy. Many of the risks linked to cannabis use are also present in the case of JWH-018, among them complications in patients suffering from cardiovascular diseases and triggering of acute psychosis. JWH-018 has not been used in therapy. Studies in mice showed anti-inflammatory and cancer chemopreventive properties of JWH-018.
CNS Activity
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL218 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10940540 |
9.0 nM [Ki] | ||
Target ID: CHEMBL253 Sources: https://www.ncbi.nlm.nih.gov/pubmed/10940540 |
2.94 nM [Ki] |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Primary | Unknown Approved UseUnknown |
|||
Preventing | Unknown Approved UseUnknown |
Sample Use Guides
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 17 19:34:59 UTC 2022
by
admin
on
Sat Dec 17 19:34:59 UTC 2022
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Record UNII |
G391998J57
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Record Status |
Validated (UNII)
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Record Version |
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-
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Classification Tree | Code System | Code | ||
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WIKIPEDIA |
Designer-drugs-JWH-018
Created by
admin on Sat Dec 17 19:34:59 UTC 2022 , Edited by admin on Sat Dec 17 19:34:59 UTC 2022
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DEA NO. |
7118
Created by
admin on Sat Dec 17 19:34:59 UTC 2022 , Edited by admin on Sat Dec 17 19:34:59 UTC 2022
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Code System | Code | Type | Description | ||
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DTXSID10175117
Created by
admin on Sat Dec 17 19:34:59 UTC 2022 , Edited by admin on Sat Dec 17 19:34:59 UTC 2022
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PRIMARY | |||
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G391998J57
Created by
admin on Sat Dec 17 19:34:59 UTC 2022 , Edited by admin on Sat Dec 17 19:34:59 UTC 2022
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PRIMARY | |||
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C552597
Created by
admin on Sat Dec 17 19:34:59 UTC 2022 , Edited by admin on Sat Dec 17 19:34:59 UTC 2022
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PRIMARY | |||
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JWH-018
Created by
admin on Sat Dec 17 19:34:59 UTC 2022 , Edited by admin on Sat Dec 17 19:34:59 UTC 2022
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PRIMARY | |||
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209414-07-3
Created by
admin on Sat Dec 17 19:34:59 UTC 2022 , Edited by admin on Sat Dec 17 19:34:59 UTC 2022
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PRIMARY | |||
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7998
Created by
admin on Sat Dec 17 19:34:59 UTC 2022 , Edited by admin on Sat Dec 17 19:34:59 UTC 2022
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PRIMARY | |||
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10382701
Created by
admin on Sat Dec 17 19:34:59 UTC 2022 , Edited by admin on Sat Dec 17 19:34:59 UTC 2022
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PRIMARY |
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TARGET -> AGONIST |
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