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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H26FN3O2
Molecular Weight 395.4707
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PX-1

SMILES

c1ccc(cc1)C[C@@]([H])(C(=N)O)N=C(c2cn(CCCCCF)c3ccccc23)O

InChI

InChIKey=DDVANTXQCRMRFF-FQEVSTJZSA-N
InChI=1S/C23H26FN3O2/c24-13-7-2-8-14-27-16-19(18-11-5-6-12-21(18)27)23(29)26-20(22(25)28)15-17-9-3-1-4-10-17/h1,3-6,9-12,16,20H,2,7-8,13-15H2,(H2,25,28)(H,26,29)/t20-/m0/s1

HIDE SMILES / InChI

Molecular Formula C23H26FN3O2
Molecular Weight 395.4707
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
83.2 nM [EC50]
PubMed

PubMed

TitleDatePubMed
Comprehensive investigation on synthetic cannabinoids: Metabolic behavior and potency testing, using 5F-APP-PICA and AMB-FUBINACA as model compounds.
2019 Sep
Substance Class Chemical
Created
by admin
on Sat Jun 26 14:24:00 UTC 2021
Edited
by admin
on Sat Jun 26 14:24:00 UTC 2021
Record UNII
BJ7SBQ2H5I
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PX-1
Code English
SRF-30
Code English
(S)-N-(1-AMINO-1-OXO-3-PHENYLPROPAN-2-YL)-1-(5-FLUOROPENTYL)-1H-INDOLE-3-CARBOXAMIDE
Systematic Name English
1H-INDOLE-3-CARBOXAMIDE, N-((1S)-2-AMINO-2-OXO-1-(PHENYLMETHYL)ETHYL)-1-(5-FLUOROPENTYL)-
Systematic Name English
5-FLUORO APP-PICA
Common Name English
N-((1S)-2-AMINO-1-BENZYL-2-OXO-ETHYL)-1-(5-FLUOROPENTYL)INDOLE-3-CARBOXAMIDE
Systematic Name English
5F-APP-PICA
Common Name English
Code System Code Type Description
WIKIPEDIA
PX-1
Created by admin on Sat Jun 26 14:24:00 UTC 2021 , Edited by admin on Sat Jun 26 14:24:00 UTC 2021
PRIMARY PX-1 (also known as 5F-APP-PICA and SRF-30) is an indole-based synthetic cannabinoid that has been sold online as a designer drug. Sweden's public health agency suggested classifying PX-1 as hazardous substance on November 10, 2014. PX-1 is listed in the Fifth Schedule of the Misuse of Drugs Act (MDA) and therefore illegal in Singapore as of May 2015.
CAS
2221100-71-4
Created by admin on Sat Jun 26 14:24:00 UTC 2021 , Edited by admin on Sat Jun 26 14:24:00 UTC 2021
PRIMARY
MANUFACTURER PRODUCT INFORMATION
5F-APP-PICA
Created by admin on Sat Jun 26 14:24:00 UTC 2021 , Edited by admin on Sat Jun 26 14:24:00 UTC 2021
PRIMARY AM2201 (Item No. 10707) is a potent synthetic cannabinoid (CB) with Ki values of 1.0 and 2.6 nM for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, respectively.1 PX 1 is a derivative of AM2201 with a PINACA-like upper chain where the isopropyl group has been replaced with a benzyl group. The physiological and toxicological properties of this compound have not been determined.
PUBCHEM
125181260
Created by admin on Sat Jun 26 14:24:00 UTC 2021 , Edited by admin on Sat Jun 26 14:24:00 UTC 2021
PRIMARY
WEB RESOURCE
5F-APP-PICA
Created by admin on Sat Jun 26 14:24:00 UTC 2021 , Edited by admin on Sat Jun 26 14:24:00 UTC 2021
PRIMARY PX-1 is also known as 5F-APP-PICA, PX-2 as 5F-APP-PINACA.
FDA UNII
BJ7SBQ2H5I
Created by admin on Sat Jun 26 14:24:00 UTC 2021 , Edited by admin on Sat Jun 26 14:24:00 UTC 2021
PRIMARY
Related Record Type Details
ACTIVE MOIETY