5F-SDB-006

FCCCCCN1C=C(C(=O)NCC2=CC=CC=C2)C3=C1C=CC=C3

InChIKey=VFLXAWVAWXHMFB-UHFFFAOYSA-N

InChI=1S/C21H23FN2O/c22-13-7-2-8-14-24-16-19(18-11-5-6-12-20(18)24)21(25)23-15-17-9-3-1-4-10-17/h1,3-6,9-12,16H,2,7-8,13-15H2,(H,23,25)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

5F-SDB-006 is a synthetic cannabinoid. It is considered to be a constituent of illicit smoking mixtures "spice".

Targets

Primary Target	Pharmacology	Condition	Potency
Cannabinoid CB1 receptor 85 Target ID: CHEMBL218 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23551277 \| https://www.ncbi.nlm.nih.gov/pubmed/27429655	Agonist 2752		71.9 nM [Ki]
Cannabinoid CB2 receptor 71 Target ID: CHEMBL253 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23551277 \| https://www.ncbi.nlm.nih.gov/pubmed/27429655	Agonist 2752		430.0 nM [Ki]

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice.	2016	27429655
The synthesis and pharmacological evaluation of adamantane-derived indoles: cannabimimetic drugs of abuse.	2013-07-17	23551277

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:49:49 GMT 2025` Edited by `admin` on `Mon Mar 31 22:49:49 GMT 2025`
Record UNII	4UP4SXX8BW
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

1H-INDOLE-3-CARBOXAMIDE, 1-(5-FLUOROPENTYL)-N-(PHENYLMETHYL)-

Preferred Name

English

5F-SDB-006

Common Name

English

N-BENZYL-1-(5-FLUOROPENTYL)-1H-INDOLE-3-CARBOXAMIDE

Systematic Name

English

Classification Tree Code System Code

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