5F-SDB-006

FCCCCCN1C=C(C(=O)NCC2=CC=CC=C2)C3=CC=CC=C13

InChIKey=VFLXAWVAWXHMFB-UHFFFAOYSA-N

InChI=1S/C21H23FN2O/c22-13-7-2-8-14-24-16-19(18-11-5-6-12-20(18)24)21(25)23-15-17-9-3-1-4-10-17/h1,3-6,9-12,16H,2,7-8,13-15H2,(H,23,25)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

5F-SDB-006 is a synthetic cannabinoid. It is considered to be a constituent of illicit smoking mixtures "spice".

Targets

Primary Target	Pharmacology	Condition	Potency
Cannabinoid CB1 receptor 85 Target ID: CHEMBL218 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23551277 \| https://www.ncbi.nlm.nih.gov/pubmed/27429655	Agonist 2678		71.9 nM [Ki]
Cannabinoid CB2 receptor 71 Target ID: CHEMBL253 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23551277 \| https://www.ncbi.nlm.nih.gov/pubmed/27429655	Agonist 2678		430.0 nM [Ki]

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
The synthesis and pharmacological evaluation of adamantane-derived indoles: cannabimimetic drugs of abuse.	2013 Jul 17	23551277
Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice.	2016	27429655

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:45:00 GMT 2023` Edited by `admin` on `Sat Dec 16 09:45:00 GMT 2023`
Record UNII	4UP4SXX8BW
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

5F-SDB-006

Common Name

English

1H-INDOLE-3-CARBOXAMIDE, 1-(5-FLUOROPENTYL)-N-(PHENYLMETHYL)-

Systematic Name

English

N-BENZYL-1-(5-FLUOROPENTYL)-1H-INDOLE-3-CARBOXAMIDE

Systematic Name

English

Classification Tree Code System Code

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