SDB-005

CCCCCN1C=C(C(=O)NC2=CC=CC=C2)C3=C1C=CC=C3

InChIKey=SPUQBSMPSCYQLS-UHFFFAOYSA-N

InChI=1S/C20H22N2O/c1-2-3-9-14-22-15-18(17-12-7-8-13-19(17)22)20(23)21-16-10-5-4-6-11-16/h4-8,10-13,15H,2-3,9,14H2,1H3,(H,21,23)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

SDB-005 is a synthetic cannabinoid. It is considered to be a constituent of illicit smoking mixtures "spice".

Targets

Primary Target	Pharmacology	Condition	Potency
Cannabinoid CB1 receptor 85 Target ID: CHEMBL218 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23551277 \| https://www.ncbi.nlm.nih.gov/pubmed/27429655	Agonist 2752		3.59 nM [Ki]
Cannabinoid CB2 receptor 71 Target ID: CHEMBL253 Sources: https://www.ncbi.nlm.nih.gov/pubmed/23551277 \| https://www.ncbi.nlm.nih.gov/pubmed/27429655	Agonist 2752		2.61 nM [Ki]

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
The synthesis and pharmacological evaluation of adamantane-derived indoles: cannabimimetic drugs of abuse.	2013 Jul 17	23551277
Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice.	2016	27429655

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:49:49 GMT 2025` Edited by `admin` on `Mon Mar 31 22:49:49 GMT 2025`
Record UNII	Z6XWV5U765
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

1H-INDOLE-3-CARBOXAMIDE, 1-PENTYL-N-PHENYL-

Preferred Name

English

SDB-005

Common Name

English

N-PHENYL-1-PENTYL-1H-INDOLE-3-CARBOXAMIDE

Systematic Name

English

Classification Tree Code System Code

WIKIPEDIA