AM-2201

FCCCCCN1C=C(C(=O)C2=CC=CC3=CC=CC=C23)C4=C1C=CC=C4

InChIKey=ALQFAGFPQCBPED-UHFFFAOYSA-N

InChI=1S/C24H22FNO/c25-15-6-1-7-16-26-17-22(20-12-4-5-14-23(20)26)24(27)21-13-8-10-18-9-2-3-11-19(18)21/h2-5,8-14,17H,1,6-7,15-16H2

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Cannabinoid CB1 receptor 85 Target ID: CHEMBL218 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25921407 \| https://legal-high-inhaltsstoffe.de/sites/default/files/uploads/am-2201.pdf \| https://www.ncbi.nlm.nih.gov/pubmed/30280499	Agonist 2752		38.0 nM [EC50]
Cannabinoid CB2 receptor 71 Target ID: CHEMBL253 Sources: https://www.ncbi.nlm.nih.gov/pubmed/25921407	Agonist 2752		2.6 nM [Ki]

PubMed

Title	Date	PubMed
Cytotoxicity of synthetic cannabinoids on primary neuronal cells of the forebrain: the involvement of cannabinoid CB1 receptors and apoptotic cell death.	2014 Jan 1	24211273
Genotoxic properties of representatives of alkylindazoles and aminoalkyl-indoles which are consumed as synthetic cannabinoids.	2015 Jun	25792264

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:41:13 GMT 2025` Edited by `admin` on `Mon Mar 31 21:41:13 GMT 2025`
Record UNII	TBJ0966F1O
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

AM-2201

Common Name

English

AM2201

Preferred Name

English

1-(5-FLUOROPENTYL)-3-(1-NAPHTHOYL)INDOLE

Systematic Name

English

JWH-2201

Code

English

METHANONE, (1-(5-FLUOROPENTYL)-1H-INDOL-3-YL)-1-NAPHTHALENYL-

Systematic Name

English

DEA NO. 7201

Code

English

J2.973.653G

Code

English

Classification Tree Code System Code

DEA NO.

7201