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Details

Stereochemistry ACHIRAL
Molecular Formula C24H23FN2O
Molecular Weight 374.4515
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 5-FLUORO-MN-24

SMILES

C(CCF)CCn1cc(c2ccccc21)C(=Nc3cccc4ccccc43)O

InChI

InChIKey=DJKVOBZLMBHFKX-UHFFFAOYSA-N
InChI=1S/C24H23FN2O/c25-15-6-1-7-16-27-17-21(20-12-4-5-14-23(20)27)24(28)26-22-13-8-10-18-9-2-3-11-19(18)22/h2-5,8-14,17H,1,6-7,15-16H2,(H,26,28)

HIDE SMILES / InChI

Molecular Formula C24H23FN2O
Molecular Weight 374.4515
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: P21554|||Q5UB37
Gene ID: 1268.0
Gene Symbol: CNR1
Target Organism: Homo sapiens (Human)
3.69 nM [Ki]
Target ID: P34972
Gene ID: 1269.0
Gene Symbol: CNR2
Target Organism: Homo sapiens (Human)
13.4 nM [Ki]
Substance Class Chemical
Created
by admin
on Sat Jun 26 14:15:39 UTC 2021
Edited
by admin
on Sat Jun 26 14:15:39 UTC 2021
Record UNII
3T22QDP4D9
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
5-FLUORO-MN-24
Common Name English
5F-NNE1
Common Name English
5F-MN-24
Common Name English
CBM-2201
Common Name English
1H-INDOLE-3-CARBOXAMIDE, 1-(5-FLUOROPENTYL)-N-1-NAPHTHALENYL-
Systematic Name English
5F-NNEI
Common Name English
1-(5-FLUOROPENTYL)-N-(1-NAPHTHYL)INDOLE-3-CARBOXAMIDE
Systematic Name English
Code System Code Type Description
WIKIPEDIA
5F-NNE1
Created by admin on Sat Jun 26 14:15:39 UTC 2021 , Edited by admin on Sat Jun 26 14:15:39 UTC 2021
PRIMARY 5F-NNE1 (also known as 5F-NNEI and 5F-MN-24) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug.(1)(2) Given the known metabolic liberation (and presence as an impurity) of amantadine in the related compound APINACA, it is suspected that metabolic hydrolysis of the amide group of 5F-NNE1 may release 1-naphthylamine, a known carcinogen.
PUBCHEM
118796566
Created by admin on Sat Jun 26 14:15:39 UTC 2021 , Edited by admin on Sat Jun 26 14:15:39 UTC 2021
PRIMARY
CAS
1445580-60-8
Created by admin on Sat Jun 26 14:15:39 UTC 2021 , Edited by admin on Sat Jun 26 14:15:39 UTC 2021
PRIMARY
FDA UNII
3T22QDP4D9
Created by admin on Sat Jun 26 14:15:39 UTC 2021 , Edited by admin on Sat Jun 26 14:15:39 UTC 2021
PRIMARY
MANUFACTURER PRODUCT INFORMATION
5-FLUORO-MN-24
Created by admin on Sat Jun 26 14:15:39 UTC 2021 , Edited by admin on Sat Jun 26 14:15:39 UTC 2021
PRIMARY 5F-MN-24 is a new chemical research compound that is an analogue to MN-24 often referred to as NNEi. The chemical formula for 5F-MN-24 is C24H23FN2O. The IUPAC name is 1-?(5-?fluoropentyl)-?N-?(naphthalen-?1-?yl)-?1H-?indole-?3-?carboxamide and the molecular mass is 374.500. Research on NNEi was conducted by ACD/Labs and ChemAxon. Properties that were predicted by ACD/Labs showed 3 #H bond acceptors, 6 #Freely rotating bonds, index of refraction at 1.616 with a surface tension of 43.6+/-7.0 dyne/cm, a flash point of 252.7.0+/-21.2 C and a boiling point of 494.3+/-18.0 C at 760 mmHg.
Related Record Type Details
TARGET -> AGONIST
Ki
TARGET -> AGONIST
Related Record Type Details
ACTIVE MOIETY