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Details

Stereochemistry ACHIRAL
Molecular Formula C23H22FN3O
Molecular Weight 375.4395
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 5-FLUORO-MN-18

SMILES

C(CCF)CCn1c2ccccc2c(C(=O)Nc3cccc4ccccc43)n1

InChI

InChIKey=XBSWUIWDRFCAGZ-UHFFFAOYSA-N
InChI=1S/C23H22FN3O/c24-15-6-1-7-16-27-21-14-5-4-12-19(21)22(26-27)23(28)25-20-13-8-10-17-9-2-3-11-18(17)20/h2-5,8-14H,1,6-7,15-16H2,(H,25,28)

HIDE SMILES / InChI

Molecular Formula C23H22FN3O
Molecular Weight 375.4395
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

5-FLUORO-MN-18 is a synthetic cannabinoid. It is considered to be a constituent of illicit smoking mixtures "spice".

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
1.65 nM [Ki]
2.5 nM [Ki]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice.
2016
Human Hepatocyte Metabolism of Novel Synthetic Cannabinoids MN-18 and Its 5-Fluoro Analog 5F-MN-18.
2017 Nov

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Jun 26 00:20:55 UTC 2021
Edited
by admin
on Sat Jun 26 00:20:55 UTC 2021
Record UNII
522ZC95042
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
5-FLUORO-MN-18
Common Name English
1H-INDAZOLE-3-CARBOXAMIDE, 1-(5-FLUOROPENTYL)-N-1-NAPHTHALENYL-
Systematic Name English
J3.314.548I
Code English
N-(1-NAPHTHYL)-1-(5-FLUOROPENTYL)-1H-INDAZOLE-3-CARBOXAMIDE
Systematic Name English
5-FLUORO-NNEI INDAZOLE ANALOG
Common Name English
5F-MN-18
Common Name English
Code System Code Type Description
FDA UNII
522ZC95042
Created by admin on Sat Jun 26 00:20:55 UTC 2021 , Edited by admin on Sat Jun 26 00:20:55 UTC 2021
PRIMARY
MANUFACTURER PRODUCT INFORMATION
5-FLUORO-MN-18
Created by admin on Sat Jun 26 00:20:55 UTC 2021 , Edited by admin on Sat Jun 26 00:20:55 UTC 2021
PRIMARY Formal Name 1-(5-fluoropentyl)-N-1-naphthalenyl-1H-indazole-3-carboxamide; CAS Number 1445581-91-8 (cayman); Molecular Formula (via cayman) C23H22FN3O
CAS
1445581-91-8
Created by admin on Sat Jun 26 00:20:55 UTC 2021 , Edited by admin on Sat Jun 26 00:20:55 UTC 2021
PRIMARY
MANUFACTURER PRODUCT INFORMATION
5-FLUORO-MN-18
Created by admin on Sat Jun 26 00:20:55 UTC 2021 , Edited by admin on Sat Jun 26 00:20:55 UTC 2021
PRIMARY SMILES O=C(NC1=C(C=CC=C2)C2=CC=C1)C3=NN(CCCCCF)C4=C3C=CC=C4; InChI Code 1S/C23H22FN3O/c24-15-6-1-7-16-27-21-14-5-4-12-19(21)22(26-27)23(28)25-20-13-8-10-17-9-2-3-11-18(17)20/h2-5,8-14H,1,6-7,15-16H2,(H,25,28); InChI Key XBSWUIWDRFCAGZ-UHFFFAOYSA-N
PUBCHEM
91936859
Created by admin on Sat Jun 26 00:20:55 UTC 2021 , Edited by admin on Sat Jun 26 00:20:55 UTC 2021
PRIMARY
Related Record Type Details
TARGET -> AGONIST
Ki
TARGET -> AGONIST
Ki
Related Record Type Details
ACTIVE MOIETY