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Details

Stereochemistry ACHIRAL
Molecular Formula C23H21FN2O
Molecular Weight 360.4249
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FUBIMINA

SMILES

C(CCF)CCn1c2ccccc2nc1C(=O)c3cccc4ccccc43

InChI

InChIKey=KUESSZMROAFKQJ-UHFFFAOYSA-N
InChI=1S/C23H21FN2O/c24-15-6-1-7-16-26-21-14-5-4-13-20(21)25-23(26)22(27)19-12-8-10-17-9-2-3-11-18(17)19/h2-5,8-14H,1,6-7,15-16H2

HIDE SMILES / InChI

Molecular Formula C23H21FN2O
Molecular Weight 360.4249
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
296.1 nM [Ki]
23.45 nM [Ki]
PubMed

PubMed

TitleDatePubMed
AB-CHMINACA, AB-PINACA, and FUBIMINA: Affinity and Potency of Novel Synthetic Cannabinoids in Producing Δ9-Tetrahydrocannabinol-Like Effects in Mice.
2015 Sep
Strategies to distinguish new synthetic cannabinoid FUBIMINA (BIM-2201) intake from its isomer THJ-2201: metabolism of FUBIMINA in human hepatocytes.
2016
Substance Class Chemical
Created
by admin
on Sat Jun 26 09:21:06 UTC 2021
Edited
by admin
on Sat Jun 26 09:21:06 UTC 2021
Record UNII
U96GD9R3UZ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FUBIMINA
Common Name English
BZ-2201
Code English
FTHJ
Common Name English
(1-(5-FLUOROPENTYL)BENZIMIDAZOL-2-YL)-(1-NAPHTHYL)METHANONE
Systematic Name English
(1-(5-FLUOROPENTYL)-1H-BENZO(D)IMIDAZOL-2-YL)(NAPHTHALEN-1-YL)METHANONE
Systematic Name English
BIM-2201
Code English
Code System Code Type Description
PUBCHEM
124519316
Created by admin on Sat Jun 26 09:21:06 UTC 2021 , Edited by admin on Sat Jun 26 09:21:06 UTC 2021
PRIMARY
FDA UNII
U96GD9R3UZ
Created by admin on Sat Jun 26 09:21:06 UTC 2021 , Edited by admin on Sat Jun 26 09:21:06 UTC 2021
PRIMARY
CAS
1984789-90-3
Created by admin on Sat Jun 26 09:21:06 UTC 2021 , Edited by admin on Sat Jun 26 09:21:06 UTC 2021
PRIMARY
WIKIPEDIA
FUBIMINA
Created by admin on Sat Jun 26 09:21:06 UTC 2021 , Edited by admin on Sat Jun 26 09:21:06 UTC 2021
PRIMARY FUBIMINA (also known as BIM-2201, BZ-2201 and FTHJ) is a synthetic cannabinoid that is the benzimidazole analog of AM-2201 and has been used as an active ingredient in synthetic cannabis products. It was first identified in Japan in 2013, alongside MEPIRAPIM. FUBIMINA acts as a reasonably potent agonist for the CB2 receptor (Ki = 23.45 nM), with 12x selectivity over CB1 (Ki = 296.1 nM), and does not fully substitute for .DELTA.9-THC in rat discrimination studies. Related benzimidazole derivatives have been reported to be highly selective agonists for the CB2 receptor.
MANUFACTURER PRODUCT INFORMATION
FUBIMINA
Created by admin on Sat Jun 26 09:21:06 UTC 2021 , Edited by admin on Sat Jun 26 09:21:06 UTC 2021
PRIMARY
Related Record Type Details
TARGET -> AGONIST
Ki
TARGET -> AGONIST
Ki
Related Record Type Details
ACTIVE MOIETY