Details
Stereochemistry | ACHIRAL |
Molecular Formula | C23H21FN2O |
Molecular Weight | 360.4249 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
C(CCF)CCn1c2ccccc2nc1C(=O)c3cccc4ccccc43
InChI
InChIKey=KUESSZMROAFKQJ-UHFFFAOYSA-N
InChI=1S/C23H21FN2O/c24-15-6-1-7-16-26-21-14-5-4-13-20(21)25-23(26)22(27)19-12-8-10-17-9-2-3-11-18(17)19/h2-5,8-14H,1,6-7,15-16H2
Molecular Formula | C23H21FN2O |
Molecular Weight | 360.4249 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL218 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26105953 |
296.1 nM [Ki] | ||
Target ID: CHEMBL253 Sources: https://www.ncbi.nlm.nih.gov/pubmed/26105953 |
23.45 nM [Ki] |
PubMed
Title | Date | PubMed |
---|---|---|
AB-CHMINACA, AB-PINACA, and FUBIMINA: Affinity and Potency of Novel Synthetic Cannabinoids in Producing Δ9-Tetrahydrocannabinol-Like Effects in Mice. | 2015 Sep |
|
Strategies to distinguish new synthetic cannabinoid FUBIMINA (BIM-2201) intake from its isomer THJ-2201: metabolism of FUBIMINA in human hepatocytes. | 2016 |
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Jun 26 09:21:06 UTC 2021
by
admin
on
Sat Jun 26 09:21:06 UTC 2021
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Record UNII |
U96GD9R3UZ
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Record Status |
Validated (UNII)
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Record Version |
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-
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Code | English | ||
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Code | English |
Code System | Code | Type | Description | ||
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124519316
Created by
admin on Sat Jun 26 09:21:06 UTC 2021 , Edited by admin on Sat Jun 26 09:21:06 UTC 2021
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U96GD9R3UZ
Created by
admin on Sat Jun 26 09:21:06 UTC 2021 , Edited by admin on Sat Jun 26 09:21:06 UTC 2021
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1984789-90-3
Created by
admin on Sat Jun 26 09:21:06 UTC 2021 , Edited by admin on Sat Jun 26 09:21:06 UTC 2021
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FUBIMINA
Created by
admin on Sat Jun 26 09:21:06 UTC 2021 , Edited by admin on Sat Jun 26 09:21:06 UTC 2021
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PRIMARY | FUBIMINA (also known as BIM-2201, BZ-2201 and FTHJ) is a synthetic cannabinoid that is the benzimidazole analog of AM-2201 and has been used as an active ingredient in synthetic cannabis products. It was first identified in Japan in 2013, alongside MEPIRAPIM. FUBIMINA acts as a reasonably potent agonist for the CB2 receptor (Ki = 23.45 nM), with 12x selectivity over CB1 (Ki = 296.1 nM), and does not fully substitute for .DELTA.9-THC in rat discrimination studies. Related benzimidazole derivatives have been reported to be highly selective agonists for the CB2 receptor. | ||
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FUBIMINA
Created by
admin on Sat Jun 26 09:21:06 UTC 2021 , Edited by admin on Sat Jun 26 09:21:06 UTC 2021
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PRIMARY |
Related Record | Type | Details | ||
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TARGET -> AGONIST |
Ki
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TARGET -> AGONIST |
Ki
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Related Record | Type | Details | ||
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ACTIVE MOIETY |