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Details

Stereochemistry ACHIRAL
Molecular Formula Fe
Molecular Weight 55.845
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 2

SHOW SMILES / InChI
Structure of FERROUS CATION

SMILES

[Fe++]

InChI

InChIKey=CWYNVVGOOAEACU-UHFFFAOYSA-N
InChI=1S/Fe/q+2

HIDE SMILES / InChI

Description
Curator's Comment: description was created based on several sources, including http://www.minapharm.com/Public/ProductDetails.aspx?ProductCode=FERRO_SANO&langParam=en

Iron(II) gluconate (also known as a ferrous gluconate) is used in the treatment of hypochromic anemia. The real problem of iron therapy is not the theoretical utilization of iron, or the reticulocyte response, or even the daily increase of hemoglobin. These are important only as they indicate the return of the patients' blood to normal in a reasonably short time without undue inconvenience. Most patients suffering from hypochromic anemia respond well to most forms of iron when administered in adequate dosage. For the patients who cannot tolerate the usual iron compounds, it is important to have a medication which is effective and which causes minimum disturbance. Ferrous gluconate is such a medicament.

Originator

Approval Year

1921
1467
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Primary
Approved
8429
Ferro Sanol Duodenal

Approved Use

Ferro Sanol is an iron substitute in case of latent or manifest iron deficiency with and without development of anaemia.
PubMed

PubMed

TitleDatePubMed
FERROUS IODIDE AND LINOLEIC ACID IN VITAMIN A DEFICIENCY. A REPLY TO CERTAIN CRITICISMS.
1932 Nov 11
THE USE OF FERROUS GLUCONATE IN THE TREATMENT OF HYPOCHROMIC ANEMIA.
1937 Jul
[Ferrous lactate as an oral iron preparation for therapeutic use].
1954 Nov 27
Clinical appraisal of drugs with special reference to a new chelate hematinic.
1957 Jul 11
[FERROUS ASPARTATE IN THERAPY].
1964 Jan 1
[Historical notes on the therapy of depression].
1986 Nov 22
Determination of water in ferrous lactate by near infrared reflectance spectroscopy with a fibre-optic probe.
1997 Oct
Decreased treatment failure rates following duodenal release ferrous glycine sulfate in iron deficiency anemia associated with autoimmune gastritis and Helicobacter pylori gastritis.
2007
Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice.
2009
Bioleaching of heavy metals from sewage sludge by indigenous iron-oxidizing microorganisms using ammonium ferrous sulfate and ferrous sulfate as energy sources: a comparative study.
2009 Nov 15
The effect of iron treatment on adhesion molecules in patients with iron deficiency anemia.
2010 Dec
Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis.
2011 Jun 10
Tolerability of different oral iron supplements: a systematic review.
2013 Apr
Effect of abomasal ferrous lactate infusion on phosphorus absorption in lactating dairy cows.
2013 Jul
A practical and successful desensitization protocol for immediate hypersensitivity reactions to iron salts.
2014
Synthesis of phosphabenzenes by an iron-catalyzed [2+2+2] cycloaddition reaction of diynes with phosphaalkynes.
2015 Jun 22
Reactivity enhancement of iron sulfide nanoparticles stabilized by sodium alginate: Taking Cr (VI) removal as an example.
2017 Jul 5
Atomic Layer Deposition of Iron Sulfide and Its Application as a Catalyst in the Hydrogenation of Azobenzenes.
2017 Mar 13
Continuous sulfidogenic wastewater treatment with iron sulfide sludge oxidation and recycle.
2017 May 1
Patents

Patents

CN105565963
36
US20020127665
36
US2009028810
36
US20150202224
36
US2877253
36
US3091626
36
US5534268
36
US6407138
36
US8080520
36
US8802114
36

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Oral
In Vitro Use Guide
Unknown
Name Type Language
FERROUS CATION
Common Name English
FE2+
Common Name English
IRON(2+) ION
Common Name English
IRON, ION (FE2+)
Common Name English
IRON(II) ION
Common Name English
FERROUS ION
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID4042672
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
RXCUI
1541238
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY RxNorm
EVMPD
SUB21940
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
SMS_ID
100000085229
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
CHEBI
29033
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
PUBCHEM
27284
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
DAILYMED
GW89581OWR
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
CAS
15438-31-0
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
FDA UNII
GW89581OWR
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
DRUG BANK
DB14510
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
ACTIVE MOIETY
Structure of FERROUS CATION
SALT/SOLVATE (PARENT)
Structure of FERROUS NITRATE HEXAHYDRATE
SALT/SOLVATE (PARENT)
Structure of FERROUS CHLORIDE
SALT/SOLVATE (PARENT)
Structure of FERROTRENINE
SALT/SOLVATE (PARENT)
Structure of FERROUS GLUCONATE
SALT/SOLVATE (PARENT)
Structure of FERROUS SULFIDE
SALT/SOLVATE (PARENT)
Structure of OLIVINE
SALT/SOLVATE (PARENT)
Structure of FERROUS OXALATE DIHYDRATE
SALT/SOLVATE (PARENT)
Structure of FERROUS HYDROXIDE
SALT/SOLVATE (PARENT)
Structure of FERROUS NICOTINATE
SALT/SOLVATE (PARENT)
Structure of FERROHEME
SALT/SOLVATE (PARENT)
Structure of FERROUS BISGLYCINATE
SALT/SOLVATE (PARENT)
Structure of SODIUM NITROPRUSSIDE
SALT/SOLVATE (PARENT)
Structure of FERROUS BROMIDE
SALT/SOLVATE (PARENT)
Structure of FERROUS OXIDE
SALT/SOLVATE (PARENT)
Structure of HEKLA LAVA
SALT/SOLVATE (PARENT)
Structure of FERROUS GLUCONATE ANHYDROUS
SALT/SOLVATE (PARENT)
Structure of FERROUS CITRATE
SALT/SOLVATE (PARENT)
Structure of FERROUS GLUTAMATE
SALT/SOLVATE (PARENT)
Structure of HEME L
SALT/SOLVATE (PARENT)
Structure of FERROUS SULFATE
SALT/SOLVATE (PARENT)
Structure of FERROUS ARSENATE
SALT/SOLVATE (PARENT)
Structure of FERROUS CARBONATE
SALT/SOLVATE (PARENT)
Structure of FERRIC FERROCYANIDE
SALT/SOLVATE (PARENT)
Structure of FERROUS FUMARATE
SALT/SOLVATE (PARENT)
Structure of FERROUS GLUCEPTATE
SALT/SOLVATE (PARENT)
Structure of FERROUS OXALATE
SALT/SOLVATE (PARENT)
Structure of FERROUS SELENIDE
SALT/SOLVATE (PARENT)
Structure of FERROUS ASPARTATE
SALT/SOLVATE (PARENT)
Structure of HEME ARGINATE
SALT/SOLVATE (PARENT)
Structure of FERROUS THIOCYANATE
SALT/SOLVATE (PARENT)
FERRUM PHOSPHORICUM
SALT/SOLVATE (PARENT)
Structure of FERROUS SULFATE MONOHYDRATE
SALT/SOLVATE (PARENT)
Structure of FERROUS DIASPARTATE
SALT/SOLVATE (PARENT)
Structure of FERROUS HYPOPHOSPHITE
SALT/SOLVATE (PARENT)
Structure of FERROUS FLUORIDE
SALT/SOLVATE (PARENT)
Structure of FERRIC SODIUM FERROCYANIDE
SALT/SOLVATE (PARENT)
Structure of FERROUS TARTRATE
SALT/SOLVATE (PARENT)
Structure of SODIUM FERROCYANIDE
SALT/SOLVATE (PARENT)
Structure of FERROUS IODIDE
SALT/SOLVATE (PARENT)
Structure of FERROCENE
SALT/SOLVATE (PARENT)
Structure of FERROUS CALCIUM CITRATE
SALT/SOLVATE (PARENT)
Structure of FERROGLYCINE SULFATE
SALT/SOLVATE (PARENT)
Structure of FERROUS SULFATE ANHYDROUS
SALT/SOLVATE (PARENT)
Structure of FERROSOFERRIC OXIDE
SALT/SOLVATE (PARENT)
Structure of FERROUS SUCCINATE
SALT/SOLVATE (PARENT)
Structure of POTASSIUM FERROCYANIDE
SALT/SOLVATE (PARENT)
Structure of FERROSOFERRIC PHOSPHATE
SALT/SOLVATE (PARENT)
Structure of FERROTRENINE ANHYDROUS
SALT/SOLVATE (PARENT)
Structure of FERROQUINE
SALT/SOLVATE (PARENT)
Structure of FERROUS ASPARTO GLYCINATE
NIH
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