FERROUS FUMARATE

First marketed in 1921

Details

Stereochemistry	ACHIRAL
Molecular Formula	C4H2O4.Fe
Molecular Weight	169.901
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Fe++].[O-]C(=O)\C=C\C([O-])=O

InChI

InChIKey=PMVSDNDAUGGCCE-TYYBGVCCSA-L

InChI=1S/C4H4O4.Fe/c5-3(6)1-2-4(7)8;/h1-2H,(H,5,6)(H,7,8);/q;+2/p-2/b2-1+;

HIDE SMILES / InChI

Molecular Formula	Fe
Molecular Weight	55.845
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C4H2O4
Molecular Weight	114.0563
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: http://www.drugfuture.com/chemdata/ferroglycine-sulfate.htmlhttp://nj.gov/health/eoh/rtkweb/documents/fs/0928.pdfhttps://www.drugs.com/inactive/ferrous-oxide-389.htmlhttp://www.druglead.com/cds/ferrous-iodide.htmlhttps://www.ncbi.nlm.nih.gov/pubmed/16694502http://www.foodchemadditives.com/products/Ferrous-Lactatehttps://www.ncbi.nlm.nih.gov/pubmed/14116934DOI: 10.1021/ja00949a016 Retrived from http://pubs.acs.org/doi/abs/10.1021/ja00949a016
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/3541174 | https://books.google.ru/books?id=7mxyBgAAQBAJ&pg=PA13&lpg=PA13&dq=%22ferrous+iodide%22+anemia&source=bl&ots=ZGyFhUiJZ4&sig=IZOhRVaGmlwX7GcqgoE6rnCsCa4&hl=ru&sa=X&ved=0ahUKEwjYu7PCyYHUAhWiQpoKHR6cCfcQ6AEIUjAJ#v=onepage&q=%22ferrous%20iodide%22&f=false

There is no information about biological and pharmacological application of Iron(II) fluoride (also known as ferrous fluoride). It is known, that this substance is used to catalyze some organic reactions.

Originator

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2596
Anemia 70 Sources: http://www.medicatione.com/?c=ing&s=ferrous%20aspartate	Palliative	Not Provided 511	Unknown Approved Use Unknown
Unknown 2596
Hypochromic anemia 37 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16694502	Palliative	Not Provided 511	Unknown Approved Use Unknown
Unknown 2596
Unknown 2596
Unknown 2596
Iron deficiency 41 Sources: http://www.minapharm.com/Public/ProductDetails.aspx?ProductCode=FERRO_SANO&langParam=en	Primary	Approved 8583	Ferro Sanol Duodenal Approved Use Ferro Sanol is an iron substitute in case of latent or manifest iron deficiency with and without development of anaemia.
Radioactive cesium and/or radioactive or non-radioactive thallium internal contamination 37 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/021626lbl.pdf	Curative	Approved 8583	RADIOGARDASE Approved Use Insoluble Prussian blue is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination. Launch Date 2003
Unknown 2596

PubMed

Title	Date	PubMed
[FERROUS ASPARTATE IN THERAPY].	1964 Jan 1	14116934
Decreased treatment failure rates following duodenal release ferrous glycine sulfate in iron deficiency anemia associated with autoimmune gastritis and Helicobacter pylori gastritis.	2007	17426393
The effect of iron treatment on adhesion molecules in patients with iron deficiency anemia.	2010 Dec	20039148
Tolerability of different oral iron supplements: a systematic review.	2013 Apr	23252877
A practical and successful desensitization protocol for immediate hypersensitivity reactions to iron salts.	2014	25402762

Patents

Sample Use Guides

In Vivo Use Guide

Adults should usually take one capsule a day. In cases of pronounced iron deficiency, adults can be given a dosage 2 to 3 times higher at the beginning of therapy. A daily dose of more than 5 mg Fe2+/kg body weight should in-well founded exceptional cases not be exceeded.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:56:02 GMT 2025` Edited by `admin` on `Mon Mar 31 17:56:02 GMT 2025`
Record UNII	R5L488RY0Q
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IRON (AS FERROUS FUMARATE)

Preferred Name

English

FERROUS FUMARATE

Official Name

English

GALFER

Common Name

English

NORQUEST FE COMPONENT FERROUS FUMARATE

Common Name

English

IRCON

Common Name

English

HEFEROL

Common Name

English

IRON FUMARATE

Systematic Name

English

FUMARIC ACID, IRON(2+) SALT (1:1)

Common Name

English

CPIRON

Common Name

English

TOLERON

Common Name

English

LO MINASTRIN FE COMPONENT FERROUS FUMARATE

Brand Name

English

2-BUTENEDIOIC ACID (E)-, IRON(2+) SALT (1:1)

Common Name

English

TOLFERAIN

Common Name

English

ORGASAL

Common Name

English

METERFER

Common Name

English

FERROUS FUMARATE [USP MONOGRAPH]

Common Name

English

FERROUS FUMARATE [II]

Common Name

English

TOLIFER

Common Name

English

IRON(II) FUMARATE

Systematic Name

English

MINASTRIN 24 FE COMPONENT FERROUS FUMARATE

Brand Name

English

FERROUS FUMARATE [VANDF]

Common Name

English

FERROUS FUMARATE [EP MONOGRAPH]

Common Name

English

HEMOTON

Common Name

English

FERROUS FUMARATE [MART.]

Common Name

English

FERROUS FUMARATE [WHO-IP]

Common Name

English

2-BUTENEDIOIC ACID (2E)-, IRON(2+) SALT (1:1)

Common Name

English

FERROSI FUMARAS [WHO-IP LATIN]

Common Name

English

ERCOFERRO

Common Name

English

FERROUS FUMARATE [JAN]

Common Name

English

FERROUS FUMARATE [MI]

Common Name

English

2-BUTENEDIOIC ACID, (E)-, IRON(2+) SALT

Common Name

English

FERROUS FUMARATE [ORANGE BOOK]

Common Name

English

IRON (AS FUMARATE)

Common Name

English

FEOSTAT

Common Name

English

IRON (AS FERROUS FUMARATE) [VANDF]

Common Name

English

ERCO-FER

Common Name

English

PALAFER

Common Name

English

Ferrous fumarate [WHO-DD]

Common Name

English

FERROFUME

Common Name

English

FERROUS FUMARATE [FCC]

Common Name

English

Classification Tree Code System Code

WHO-ATC

B03AD02