U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula Fe
Molecular Weight 55.845
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 2

SHOW SMILES / InChI
Structure of FERROUS CATION

SMILES

[Fe++]

InChI

InChIKey=CWYNVVGOOAEACU-UHFFFAOYSA-N
InChI=1S/Fe/q+2

HIDE SMILES / InChI

Molecular Formula Fe
Molecular Weight 55.845
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Iron(II) gluconate (also known as a ferrous gluconate) is used in the treatment of hypochromic anemia. The real problem of iron therapy is not the theoretical utilization of iron, or the reticulocyte response, or even the daily increase of hemoglobin. These are important only as they indicate the return of the patients' blood to normal in a reasonably short time without undue inconvenience. Most patients suffering from hypochromic anemia respond well to most forms of iron when administered in adequate dosage. For the patients who cannot tolerate the usual iron compounds, it is important to have a medication which is effective and which causes minimum disturbance. Ferrous gluconate is such a medicament.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Unknown

Approved Use

Unknown
Palliative
Unknown

Approved Use

Unknown
Primary
Ferro Sanol Duodenal

Approved Use

Ferro Sanol is an iron substitute in case of latent or manifest iron deficiency with and without development of anaemia.
PubMed

PubMed

TitleDatePubMed
FERROUS IODIDE AS A SUBSTITUTE FOR VITAMIN A IN RATS.
1932 Jul 1
FERROUS IODIDE AND LINOLEIC ACID IN VITAMIN A DEFICIENCY. A REPLY TO CERTAIN CRITICISMS.
1932 Nov 11
THE ADMINISTRATION OF FERROUS IODIDE AND LINOLEIC ACID TO RATS DEPRIVED OF VITAMIN A.
1932 Sep 30
Clinical appraisal of drugs with special reference to a new chelate hematinic.
1957 Jul 11
[FERROUS ASPARTATE IN THERAPY].
1964 Jan 1
Decreased treatment failure rates following duodenal release ferrous glycine sulfate in iron deficiency anemia associated with autoimmune gastritis and Helicobacter pylori gastritis.
2007
Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice.
2009
Bioleaching of heavy metals from sewage sludge by indigenous iron-oxidizing microorganisms using ammonium ferrous sulfate and ferrous sulfate as energy sources: a comparative study.
2009 Nov 15
The effect of iron treatment on adhesion molecules in patients with iron deficiency anemia.
2010 Dec
Tolerability of different oral iron supplements: a systematic review.
2013 Apr
A practical and successful desensitization protocol for immediate hypersensitivity reactions to iron salts.
2014
Synthesis of phosphabenzenes by an iron-catalyzed [2+2+2] cycloaddition reaction of diynes with phosphaalkynes.
2015 Jun 22
Reactivity enhancement of iron sulfide nanoparticles stabilized by sodium alginate: Taking Cr (VI) removal as an example.
2017 Jul 5
Continuous sulfidogenic wastewater treatment with iron sulfide sludge oxidation and recycle.
2017 May 1
Patents

Sample Use Guides

Unknown
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 19:47:09 GMT 2023
Edited
by admin
on Fri Dec 15 19:47:09 GMT 2023
Record UNII
GW89581OWR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERROUS CATION
Common Name English
FE2+
Common Name English
IRON(2+) ION
Common Name English
IRON, ION (FE2+)
Common Name English
IRON(II) ION
Common Name English
FERROUS ION
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID4042672
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
RXCUI
1541238
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY RxNorm
EVMPD
SUB21940
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
SMS_ID
100000085229
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
CHEBI
29033
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
PUBCHEM
27284
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
DAILYMED
GW89581OWR
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
CAS
15438-31-0
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
FDA UNII
GW89581OWR
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
DRUG BANK
DB14510
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
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