U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula Fe
Molecular Weight 55.845
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 2

SHOW SMILES / InChI
Structure of FERROUS CATION

SMILES

[Fe++]

InChI

InChIKey=CWYNVVGOOAEACU-UHFFFAOYSA-N
InChI=1S/Fe/q+2

HIDE SMILES / InChI

Molecular Formula Fe
Molecular Weight 55.845
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Iron(II) gluconate (also known as a ferrous gluconate) is used in the treatment of hypochromic anemia. The real problem of iron therapy is not the theoretical utilization of iron, or the reticulocyte response, or even the daily increase of hemoglobin. These are important only as they indicate the return of the patients' blood to normal in a reasonably short time without undue inconvenience. Most patients suffering from hypochromic anemia respond well to most forms of iron when administered in adequate dosage. For the patients who cannot tolerate the usual iron compounds, it is important to have a medication which is effective and which causes minimum disturbance. Ferrous gluconate is such a medicament.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Unknown

Approved Use

Unknown
Palliative
Unknown

Approved Use

Unknown
Primary
Ferro Sanol Duodenal

Approved Use

Ferro Sanol is an iron substitute in case of latent or manifest iron deficiency with and without development of anaemia.
PubMed

PubMed

TitleDatePubMed
THE USE OF FERROUS GLUCONATE IN THE TREATMENT OF HYPOCHROMIC ANEMIA.
1937 Jul
[Ferrous lactate as an oral iron preparation for therapeutic use].
1954 Nov 27
Clinical appraisal of drugs with special reference to a new chelate hematinic.
1957 Jul 11
Decreased treatment failure rates following duodenal release ferrous glycine sulfate in iron deficiency anemia associated with autoimmune gastritis and Helicobacter pylori gastritis.
2007
The effect of iron treatment on adhesion molecules in patients with iron deficiency anemia.
2010 Dec
Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis.
2011 Jun 10
Effect of abomasal ferrous lactate infusion on phosphorus absorption in lactating dairy cows.
2013 Jul
Atomic Layer Deposition of Iron Sulfide and Its Application as a Catalyst in the Hydrogenation of Azobenzenes.
2017 Mar 13
Patents

Sample Use Guides

Unknown
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 19:47:09 GMT 2023
Edited
by admin
on Fri Dec 15 19:47:09 GMT 2023
Record UNII
GW89581OWR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERROUS CATION
Common Name English
FE2+
Common Name English
IRON(2+) ION
Common Name English
IRON, ION (FE2+)
Common Name English
IRON(II) ION
Common Name English
FERROUS ION
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID4042672
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
RXCUI
1541238
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY RxNorm
EVMPD
SUB21940
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
SMS_ID
100000085229
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
CHEBI
29033
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
PUBCHEM
27284
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
DAILYMED
GW89581OWR
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
CAS
15438-31-0
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
FDA UNII
GW89581OWR
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
DRUG BANK
DB14510
Created by admin on Fri Dec 15 19:47:13 GMT 2023 , Edited by admin on Fri Dec 15 19:47:13 GMT 2023
PRIMARY
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