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Details

Stereochemistry ACHIRAL
Molecular Formula 2Cl.Fe
Molecular Weight 126.751
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERROUS CHLORIDE

SMILES

[Cl-].[Cl-].[Fe++]

InChI

InChIKey=NMCUIPGRVMDVDB-UHFFFAOYSA-L
InChI=1S/2ClH.Fe/h2*1H;/q;;+2/p-2

HIDE SMILES / InChI
Molecular Formula Fe
Molecular Weight 55.845
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including http://www.minapharm.com/Public/ProductDetails.aspx?ProductCode=FERRO_SANO&langParam=en

Iron(II) gluconate (also known as a ferrous gluconate) is used in the treatment of hypochromic anemia. The real problem of iron therapy is not the theoretical utilization of iron, or the reticulocyte response, or even the daily increase of hemoglobin. These are important only as they indicate the return of the patients' blood to normal in a reasonably short time without undue inconvenience. Most patients suffering from hypochromic anemia respond well to most forms of iron when administered in adequate dosage. For the patients who cannot tolerate the usual iron compounds, it is important to have a medication which is effective and which causes minimum disturbance. Ferrous gluconate is such a medicament.

Originator

Approval Year

1921
1467
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Primary
Approved
8429
Ferro Sanol Duodenal

Approved Use

Ferro Sanol is an iron substitute in case of latent or manifest iron deficiency with and without development of anaemia.
PubMed

PubMed

TitleDatePubMed
THE USE OF FERROUS GLUCONATE IN THE TREATMENT OF HYPOCHROMIC ANEMIA.
1937 Jul
[Ferrous lactate as an oral iron preparation for therapeutic use].
1954 Nov 27
[FERROUS ASPARTATE IN THERAPY].
1964 Jan 1
Determination of water in ferrous lactate by near infrared reflectance spectroscopy with a fibre-optic probe.
1997 Oct
Decreased treatment failure rates following duodenal release ferrous glycine sulfate in iron deficiency anemia associated with autoimmune gastritis and Helicobacter pylori gastritis.
2007
Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice.
2009
The effect of iron treatment on adhesion molecules in patients with iron deficiency anemia.
2010 Dec
Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis.
2011 Jun 10
Tolerability of different oral iron supplements: a systematic review.
2013 Apr
Reactivity enhancement of iron sulfide nanoparticles stabilized by sodium alginate: Taking Cr (VI) removal as an example.
2017 Jul 5
Continuous sulfidogenic wastewater treatment with iron sulfide sludge oxidation and recycle.
2017 May 1
Patents

Patents

CN105565963
36
US20020127665
36
US2009028810
36
US20150202224
36
US2877253
36
US3091626
36
US5534268
36
US6407138
36
US8080520
36
US8802114
36

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:30:58 UTC 2023
Edited
by admin
on Fri Dec 15 15:30:58 UTC 2023
Record UNII
S3Y25PHP1W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERROUS CHLORIDE
HSDB   MART.   MI   WHO-DD  
Common Name English
FERROUS CHLORIDE [HSDB]
Common Name English
FERROUS CHLORIDE [MART.]
Common Name English
FERROUS CHLORIDE [MI]
Common Name English
IRON(II) CHLORIDE
Systematic Name English
Ferrous chloride [WHO-DD]
Common Name English
Classification Tree Code System Code
WHO-VATC QB03AA05
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
WHO-ATC B03AA05
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
Code System Code Type Description
NCI_THESAURUS
C45678
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
CONCEPT Industrial Aid
PUBCHEM
24458
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
HSDB
459
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
MESH
C029451
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
RXCUI
24940
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY RxNorm
SMS_ID
100000091052
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
DRUG BANK
DB13569
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
EVMPD
SUB13863MIG
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
ECHA (EC/EINECS)
231-843-4
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
EPA CompTox
DTXSID9029695
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
CAS
7758-94-3
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
WIKIPEDIA
Ferrous chloride
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
DRUG CENTRAL
4543
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
CAS
12040-57-2
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
NON-SPECIFIC STOICHIOMETRY
FDA UNII
S3Y25PHP1W
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
NCI_THESAURUS
C83715
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
MERCK INDEX
m5340
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY Merck Index
ChEMBL
CHEMBL3183704
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
CHEBI
30812
Created by admin on Fri Dec 15 15:30:58 UTC 2023 , Edited by admin on Fri Dec 15 15:30:58 UTC 2023
PRIMARY
Related Record Type Details
Structure of FERROUS CATION
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of FERROUS CATION
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
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DISCLAIMER
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