FERROGLYCINE SULFATE

First marketed in 1921

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H5NO2.Fe.O4S
Molecular Weight	226.974
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Fe++].NCC(O)=O.[O-]S([O-])(=O)=O

InChI

InChIKey=ZITFTYGHYGPDAV-UHFFFAOYSA-L

InChI=1S/C2H5NO2.Fe.H2O4S/c3-1-2(4)5;;1-5(2,3)4/h1,3H2,(H,4,5);;(H2,1,2,3,4)/q;+2;/p-2

HIDE SMILES / InChI

Molecular Formula	Fe
Molecular Weight	55.845
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C2H4NO2
Molecular Weight	74.0587
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	HO4S
Molecular Weight	97.071
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.drugfuture.com/chemdata/ferroglycine-sulfate.htmlhttp://nj.gov/health/eoh/rtkweb/documents/fs/0928.pdfhttps://www.drugs.com/inactive/ferrous-oxide-389.htmlhttp://www.druglead.com/cds/ferrous-iodide.htmlhttps://www.ncbi.nlm.nih.gov/pubmed/16694502http://www.foodchemadditives.com/products/Ferrous-Lactatehttps://www.ncbi.nlm.nih.gov/pubmed/14116934DOI: 10.1021/ja00949a016 Retrived from http://pubs.acs.org/doi/abs/10.1021/ja00949a016
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/3541174 | https://books.google.ru/books?id=7mxyBgAAQBAJ&pg=PA13&lpg=PA13&dq=%22ferrous+iodide%22+anemia&source=bl&ots=ZGyFhUiJZ4&sig=IZOhRVaGmlwX7GcqgoE6rnCsCa4&hl=ru&sa=X&ved=0ahUKEwjYu7PCyYHUAhWiQpoKHR6cCfcQ6AEIUjAJ#v=onepage&q=%22ferrous%20iodide%22&f=false

There is no information about biological and pharmacological application of Iron(II) fluoride (also known as ferrous fluoride). It is known, that this substance is used to catalyze some organic reactions.

Originator

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2596
Anemia 70 Sources: http://www.medicatione.com/?c=ing&s=ferrous%20aspartate	Palliative	Not Provided 511	Unknown Approved Use Unknown
Unknown 2596
Hypochromic anemia 37 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16694502	Palliative	Not Provided 511	Unknown Approved Use Unknown
Unknown 2596
Unknown 2596
Unknown 2596
Iron deficiency 41 Sources: http://www.minapharm.com/Public/ProductDetails.aspx?ProductCode=FERRO_SANO&langParam=en	Primary	Approved 8583	Ferro Sanol Duodenal Approved Use Ferro Sanol is an iron substitute in case of latent or manifest iron deficiency with and without development of anaemia.
Radioactive cesium and/or radioactive or non-radioactive thallium internal contamination 37 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/021626lbl.pdf	Curative	Approved 8583	RADIOGARDASE Approved Use Insoluble Prussian blue is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination. Launch Date 2003
Unknown 2596

PubMed

Title	Date	PubMed
THE USE OF FERROUS GLUCONATE IN THE TREATMENT OF HYPOCHROMIC ANEMIA.	1937 Jul	16694502
[Ferrous lactate as an oral iron preparation for therapeutic use].	1954 Nov 27	14348915
Determination of water in ferrous lactate by near infrared reflectance spectroscopy with a fibre-optic probe.	1997 Oct	9408841
Tolerability of different oral iron supplements: a systematic review.	2013 Apr	23252877
Effect of abomasal ferrous lactate infusion on phosphorus absorption in lactating dairy cows.	2013 Jul	23660146
A practical and successful desensitization protocol for immediate hypersensitivity reactions to iron salts.	2014	25402762
Synthesis of phosphabenzenes by an iron-catalyzed [2+2+2] cycloaddition reaction of diynes with phosphaalkynes.	2015 Jun 22	25981197
Reactivity enhancement of iron sulfide nanoparticles stabilized by sodium alginate: Taking Cr (VI) removal as an example.	2017 Jul 5	28371713
Atomic Layer Deposition of Iron Sulfide and Its Application as a Catalyst in the Hydrogenation of Azobenzenes.	2017 Mar 13	28170144
Continuous sulfidogenic wastewater treatment with iron sulfide sludge oxidation and recycle.	2017 May 1	28249212

Patents

Sample Use Guides

In Vivo Use Guide

Adults should usually take one capsule a day. In cases of pronounced iron deficiency, adults can be given a dosage 2 to 3 times higher at the beginning of therapy. A daily dose of more than 5 mg Fe2+/kg body weight should in-well founded exceptional cases not be exceeded.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:07:14 GMT 2025` Edited by `admin` on `Mon Mar 31 18:07:14 GMT 2025`
Record UNII	JGK960078D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FERROGLYCINE SULFATE

Common Name

English

FERROGLYCINE SULFATE COMPLEX

Preferred Name

English

(T-4)-(GLYCINATO-.KAPPA.N,.KAPPA.O) (SULFATO(2-)-.KAPPA.O,.KAPPA.O')FERRATE(1-) HYDROGEN (1:1)

Common Name

English

FERROCONTIN

Brand Name

English

FERROGLYCINE SULPHATE

Common Name

English

Ferroglycine sulfate complex [WHO-DD]

Common Name

English

FERROGLYCINE SULFATE [MI]

Common Name

English

FERRATE(1-), (GLYCINATO-.KAPPA.N,.KAPPA.O)(SULFATO(2-)-.KAPPA.O,.KAPPA.O')-, HYDROGEN (1:1), (T-4)-

Systematic Name

English

FERROSANOL

Brand Name

English

FERROUS AMINOACETOSULFATE

Common Name

English

IRON SULFATE-GLYCINE COMPLEX

Common Name

English

PLESMET

Brand Name

English

Code System Code Type Description

PUBCHEM

28366