U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula Fe.O4S.7H2O
Molecular Weight 278.015
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERROUS SULFATE

SMILES

O.O.O.O.O.O.O.[Fe++].[O-]S([O-])(=O)=O

InChI

InChIKey=SURQXAFEQWPFPV-UHFFFAOYSA-L
InChI=1S/Fe.H2O4S.7H2O/c;1-5(2,3)4;;;;;;;/h;(H2,1,2,3,4);7*1H2/q+2;;;;;;;;/p-2

HIDE SMILES / InChI
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula H2O4S
Molecular Weight 98.078
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Fe
Molecular Weight 55.845
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/3541174 | https://books.google.ru/books?id=7mxyBgAAQBAJ&pg=PA13&lpg=PA13&dq=%22ferrous+iodide%22+anemia&source=bl&ots=ZGyFhUiJZ4&sig=IZOhRVaGmlwX7GcqgoE6rnCsCa4&hl=ru&sa=X&ved=0ahUKEwjYu7PCyYHUAhWiQpoKHR6cCfcQ6AEIUjAJ#v=onepage&q=%22ferrous%20iodide%22&f=false

There is no information about biological and pharmacological application of Iron(II) fluoride (also known as ferrous fluoride). It is known, that this substance is used to catalyze some organic reactions.

Originator

Approval Year

1921
1468
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Not Provided
511
Unknown

Approved Use

Unknown
Palliative
Not Provided
511
Unknown

Approved Use

Unknown
Primary
Approved
8583
Ferro Sanol Duodenal

Approved Use

Ferro Sanol is an iron substitute in case of latent or manifest iron deficiency with and without development of anaemia.
Curative
Approved
8583
RADIOGARDASE

Approved Use

Insoluble Prussian blue is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination.

Launch Date

2003
PubMed

PubMed

TitleDatePubMed
Reactivity enhancement of iron sulfide nanoparticles stabilized by sodium alginate: Taking Cr (VI) removal as an example.
2017-07-05
Continuous sulfidogenic wastewater treatment with iron sulfide sludge oxidation and recycle.
2017-05-01
Atomic Layer Deposition of Iron Sulfide and Its Application as a Catalyst in the Hydrogenation of Azobenzenes.
2017-03-13
Synthesis of phosphabenzenes by an iron-catalyzed [2+2+2] cycloaddition reaction of diynes with phosphaalkynes.
2015-06-22
A practical and successful desensitization protocol for immediate hypersensitivity reactions to iron salts.
2014
Effect of abomasal ferrous lactate infusion on phosphorus absorption in lactating dairy cows.
2013-07
Tolerability of different oral iron supplements: a systematic review.
2013-04
Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis.
2011-06-10
The effect of iron treatment on adhesion molecules in patients with iron deficiency anemia.
2010-12
Bioleaching of heavy metals from sewage sludge by indigenous iron-oxidizing microorganisms using ammonium ferrous sulfate and ferrous sulfate as energy sources: a comparative study.
2009-11-15
Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice.
2009
Decreased treatment failure rates following duodenal release ferrous glycine sulfate in iron deficiency anemia associated with autoimmune gastritis and Helicobacter pylori gastritis.
2007
Determination of water in ferrous lactate by near infrared reflectance spectroscopy with a fibre-optic probe.
1997-10
[Historical notes on the therapy of depression].
1986-11-22
[FERROUS ASPARTATE IN THERAPY].
1964-01-01
Clinical appraisal of drugs with special reference to a new chelate hematinic.
1957-07-11
[Ferrous lactate as an oral iron preparation for therapeutic use].
1954-11-27
THE USE OF FERROUS GLUCONATE IN THE TREATMENT OF HYPOCHROMIC ANEMIA.
1937-07
FERROUS IODIDE AND LINOLEIC ACID IN VITAMIN A DEFICIENCY. A REPLY TO CERTAIN CRITICISMS.
1932-11-11
THE ADMINISTRATION OF FERROUS IODIDE AND LINOLEIC ACID TO RATS DEPRIVED OF VITAMIN A.
1932-09-30
FERROUS IODIDE AS A SUBSTITUTE FOR VITAMIN A IN RATS.
1932-07-01
Patents

Patents

CN105565963
37
US20020127665
37
US2009028810
37
US20150202224
37
US2877253
37
US3091626
37
US5534268
37
US6407138
37
US8080520
37
US8802114
37

Sample Use Guides

In Vivo Use Guide
Adults should usually take one capsule a day. In cases of pronounced iron deficiency, adults can be given a dosage 2 to 3 times higher at the beginning of therapy. A daily dose of more than 5 mg Fe2+/kg body weight should in-well founded exceptional cases not be exceeded.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:58:12 GMT 2025
Edited
by admin
on Mon Mar 31 17:58:12 GMT 2025
Record UNII
39R4TAN1VT
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERROUS SULFATE HEPTAHYDRATE
EP   MI   WHO-DD   WHO-IP  
Preferred Name English
FERROUS SULFATE
FCC   INCI   MART.   ORANGE BOOK   USP   USP-RS   VANDF   WHO-IP  
INCI  
Official Name English
IRON(II) SULPHATE (1:1), HEPTAHYDRATE
Common Name English
FERRUM SULPHURICUM
HPUS  
Common Name English
FEOSOL
Brand Name English
HAEMOFORT
Brand Name English
FERROUS SULFATE HEPTAHYDRATE [WHO-IP]
Common Name English
FERRUM SULPHURICUM [HPUS]
Common Name English
FERROUS SULFATE HEPTAHYDRATE [MI]
Common Name English
FERROUS SULFATE, EXSICCATED [WHO-IP]
Common Name English
FERROUS SULFATE [MART.]
Common Name English
IRON (AS FERROUS SULFATE) [VANDF]
Common Name English
SULFURIC ACID, IRON(2+) SALT (1:1), HEPTAHYDRATE
Common Name English
FERROUS SULFATE [USP MONOGRAPH]
Common Name English
FERROUS SULFATE [ORANGE BOOK]
Common Name English
Iron(2+) sulfate (1:1) heptahydrate
Common Name English
FESOFOR
Brand Name English
FERROUS SULFATE HYDRATE
JAN  
Common Name English
FERO-GRADUMET
Brand Name English
FERROUS SULFATE [VANDF]
Common Name English
FERROUS SULFATE HEPTAHYDRATE [EP MONOGRAPH]
Common Name English
MOL-IRON
Brand Name English
SULFERROUS
Brand Name English
FERROUS SULPHATE HEPTAHYDRATE
Common Name English
FERROUS SULFATE [USP-RS]
Common Name English
FER-IN-SOL
Brand Name English
Ferrous sulfate heptahydrate [WHO-DD]
Common Name English
PRESFERSUL
Brand Name English
FOLVRON COMPONENT FERROUS SULFATE
Common Name English
IRONATE
Brand Name English
COPPERAS
Brand Name English
FERROUS SULPHATE
Common Name English
GREEN VITRIOL
Common Name English
FERROUS SULFATE [FCC]
Common Name English
IRON(II) SULPHATE HEPTAHYDRATE
Systematic Name English
FERROUS SULFATE HYDRATE [JAN]
Common Name English
IRON(2+) SULPHATE (1:1) HEPTAHYDRATE
Common Name English
IRON VITRIOL
Common Name English
FERROUS SULFATE [WHO-IP]
Common Name English
FEOSPAN
Brand Name English
FERROSI SULFAS [WHO-IP LATIN]
Common Name English
IRON(II) SULFATE (1:1), HEPTAHYDRATE
Common Name English
IRON(II) SULFATE HEPTAHYDRATE
Systematic Name English
FERROUS II SULFATE HEPTAHYDRATE
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 50502
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
WHO-ATC B03AD03
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
CFR 21 CFR 184.1315
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
LIVERTOX 407
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
WHO-VATC QB03AA07
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
WHO-ATC B03AA07
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
WHO-VATC QB03AD03
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
Code System Code Type Description
RS_ITEM_NUM
1270355
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
EPA CompTox
DTXSID9040344
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
EVMPD
SUB126949
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
CHEBI
75832
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
CAS
7782-63-0
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
PUBCHEM
62662
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
FERROUS SULFATE
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY Description: Exsiccated Ferrous sulfate is a greyish white powder; Ferrous sulfate heptahydrate has pale blue-green prisms or isa pale green, crystalline powder; both forms are odourless.Solubility: Exsiccated Ferrous sulfate is slowly but almost completely soluble in carbon-dioxide-free water R; practically insolublein ethanol (~750 g/l) TS. Ferrous sulfate heptahydrate is freely soluble in water; very soluble in boiling water; practically insolublein ethanol (~750 g/l) TS.Category. Haemopoietic (iron-deficiency anaemia).Storage: Ferrous sulfate should be kept in a well-closed container.Labelling: The designation on the container of Ferrous sulfate should state whether the substance is in the exsiccated form or isthe heptahydrate.
NCI_THESAURUS
C29049
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
DRUG CENTRAL
4528
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
EVMPD
SUB21826
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
SMS_ID
100000087595
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
MESH
C020748
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
DAILYMED
39R4TAN1VT
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
ChEMBL
CHEMBL1200830
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
CHEBI
75836
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
FDA UNII
39R4TAN1VT
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
RXCUI
24947
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY RxNorm
WIKIPEDIA
Ferrous sulfate
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
EVMPD
SUB13877MIG
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
MERCK INDEX
m5354
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY Merck Index
DRUG BANK
DBSALT002666
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
PRIMARY
NCI_THESAURUS
C1505
Created by admin on Mon Mar 31 17:58:12 GMT 2025 , Edited by admin on Mon Mar 31 17:58:12 GMT 2025
CONCEPT Dietary Supplement
Related Record Type Details
Structure of FERROUS SULFATE ANHYDROUS
ANHYDROUS->SOLVATE
Structure of FERROUS CATION
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of FERROUS CATION
ACTIVE MOIETY
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966