FERROUS SULFATE ANHYDROUS

First marketed in 1921

Details

Stereochemistry	ACHIRAL
Molecular Formula	Fe.O4S
Molecular Weight	151.908
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Fe++].[O-]S([O-])(=O)=O

InChI

InChIKey=BAUYGSIQEAFULO-UHFFFAOYSA-L

InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2

HIDE SMILES / InChI

Molecular Formula	O4S
Molecular Weight	96.063
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Fe
Molecular Weight	55.845
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14116934http://www.foodchemadditives.com/products/Ferrous-Lactatehttp://nj.gov/health/eoh/rtkweb/documents/fs/0928.pdfDOI: 10.1021/ja00949a016 Retrived from http://pubs.acs.org/doi/abs/10.1021/ja00949a016https://www.drugs.com/inactive/ferrous-oxide-389.htmlhttp://www.druglead.com/cds/ferrous-iodide.htmlhttp://www.drugfuture.com/chemdata/ferroglycine-sulfate.htmlhttps://www.ncbi.nlm.nih.gov/pubmed/16694502
Curator's Comment: description was created based on several sources, including http://www.minapharm.com/Public/ProductDetails.aspx?ProductCode=FERRO_SANO&langParam=en

Iron(II) gluconate (also known as a ferrous gluconate) is used in the treatment of hypochromic anemia. The real problem of iron therapy is not the theoretical utilization of iron, or the reticulocyte response, or even the daily increase of hemoglobin. These are important only as they indicate the return of the patients' blood to normal in a reasonably short time without undue inconvenience. Most patients suffering from hypochromic anemia respond well to most forms of iron when administered in adequate dosage. For the patients who cannot tolerate the usual iron compounds, it is important to have a medication which is effective and which causes minimum disturbance. Ferrous gluconate is such a medicament.

Originator

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2578
Anemia 68 Sources: http://www.medicatione.com/?c=ing&s=ferrous%20aspartate	Palliative	Not Provided 504	Unknown Approved Use Unknown
Unknown 2578
Hypochromic anemia 36 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16694502	Palliative	Not Provided 504	Unknown Approved Use Unknown
Unknown 2578
Unknown 2578
Unknown 2578
Iron deficiency 80 Sources: http://www.minapharm.com/Public/ProductDetails.aspx?ProductCode=FERRO_SANO&langParam=en	Primary	Approved 8429	Ferro Sanol Duodenal Approved Use Ferro Sanol is an iron substitute in case of latent or manifest iron deficiency with and without development of anaemia.
Unknown 2578

PubMed

Title	Date	PubMed
FERROUS IODIDE AS A SUBSTITUTE FOR VITAMIN A IN RATS.	1932 Jul 1	17815234
FERROUS IODIDE AND LINOLEIC ACID IN VITAMIN A DEFICIENCY. A REPLY TO CERTAIN CRITICISMS.	1932 Nov 11	17744342
[Ferrous lactate as an oral iron preparation for therapeutic use].	1954 Nov 27	14348915
Clinical appraisal of drugs with special reference to a new chelate hematinic.	1957 Jul 11	13452048
[FERROUS ASPARTATE IN THERAPY].	1964 Jan 1	14116934
[Historical notes on the therapy of depression].	1986 Nov 22	3541174
Determination of water in ferrous lactate by near infrared reflectance spectroscopy with a fibre-optic probe.	1997 Oct	9408841
Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice.	2009	19421372
The effect of iron treatment on adhesion molecules in patients with iron deficiency anemia.	2010 Dec	20039148
Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis.	2011 Jun 10	21439359
Tolerability of different oral iron supplements: a systematic review.	2013 Apr	23252877
Effect of abomasal ferrous lactate infusion on phosphorus absorption in lactating dairy cows.	2013 Jul	23660146
Reactivity enhancement of iron sulfide nanoparticles stabilized by sodium alginate: Taking Cr (VI) removal as an example.	2017 Jul 5	28371713
Atomic Layer Deposition of Iron Sulfide and Its Application as a Catalyst in the Hydrogenation of Azobenzenes.	2017 Mar 13	28170144
Continuous sulfidogenic wastewater treatment with iron sulfide sludge oxidation and recycle.	2017 May 1	28249212

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:28:17 UTC 2023` Edited by `admin` on `Fri Dec 15 15:28:17 UTC 2023`
Record UNII	2IDP3X9OUD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FERROUS SULFATE ANHYDROUS

Common Name

English

NSC-57631

Code

English

IRON SULFATE

Systematic Name

English

IRON(II) SULPHATE (1:1)

Systematic Name

English

FERROUS SULFATE,DRIED [VANDF]

Common Name

English

FERROUS SULFATE (1:1)

Common Name

English

FERROUS SULFATE [HSDB]

Common Name

English

IRON(II) SULFATE

Systematic Name

English

FERROUS SULFATE [MI]

Common Name

English

IRON (AS SULPHATE)

Common Name

English

FERROUS SULFATE [ISO]

Common Name

English

FERROUS SULFATE, ANHYDROUS

Common Name

English

FERROUS SULPHATE (1:1)

Common Name

English

IRON SULPHATE (FESO4)

Common Name

English

FERROUS SULPHATE ANHYDROUS

Common Name

English

SULFURIC ACID, IRON(2+) SALT (1:1)

Common Name

English

FERROUS SULPHATE, ANHYDROUS

Common Name

English

IRON SULFATE (FESO4)

Common Name

English

NSC-146177

Code

English

FERROUS SULFATE,DRIED

Common Name

English

Ferrous sulfate [WHO-DD]

Common Name

English

IRON(II) SULFATE (1:1)

Systematic Name

English

Code System Code Type Description

CHEBI

75832