U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula 2Fe.2O4S.3H2O
Molecular Weight 357.861
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERROUS SULFATE SESQUIHYDRATE

SMILES

O.O.O.[Fe++].[Fe++].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O

InChI

InChIKey=JJUUPAANEJLKEY-UHFFFAOYSA-J
InChI=1S/2Fe.2H2O4S.3H2O/c;;2*1-5(2,3)4;;;/h;;2*(H2,1,2,3,4);3*1H2/q2*+2;;;;;/p-4

HIDE SMILES / InChI

Molecular Formula O4S
Molecular Weight 96.063
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Fe
Molecular Weight 55.845
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Iron(II) gluconate (also known as a ferrous gluconate) is used in the treatment of hypochromic anemia. The real problem of iron therapy is not the theoretical utilization of iron, or the reticulocyte response, or even the daily increase of hemoglobin. These are important only as they indicate the return of the patients' blood to normal in a reasonably short time without undue inconvenience. Most patients suffering from hypochromic anemia respond well to most forms of iron when administered in adequate dosage. For the patients who cannot tolerate the usual iron compounds, it is important to have a medication which is effective and which causes minimum disturbance. Ferrous gluconate is such a medicament.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Unknown

Approved Use

Unknown
Palliative
Unknown

Approved Use

Unknown
Primary
Ferro Sanol Duodenal

Approved Use

Ferro Sanol is an iron substitute in case of latent or manifest iron deficiency with and without development of anaemia.
PubMed

PubMed

TitleDatePubMed
THE USE OF FERROUS GLUCONATE IN THE TREATMENT OF HYPOCHROMIC ANEMIA.
1937 Jul
[Ferrous lactate as an oral iron preparation for therapeutic use].
1954 Nov 27
Clinical appraisal of drugs with special reference to a new chelate hematinic.
1957 Jul 11
[FERROUS ASPARTATE IN THERAPY].
1964 Jan 1
Determination of water in ferrous lactate by near infrared reflectance spectroscopy with a fibre-optic probe.
1997 Oct
Decreased treatment failure rates following duodenal release ferrous glycine sulfate in iron deficiency anemia associated with autoimmune gastritis and Helicobacter pylori gastritis.
2007
The effect of iron treatment on adhesion molecules in patients with iron deficiency anemia.
2010 Dec
Tolerability of different oral iron supplements: a systematic review.
2013 Apr
Effect of abomasal ferrous lactate infusion on phosphorus absorption in lactating dairy cows.
2013 Jul
A practical and successful desensitization protocol for immediate hypersensitivity reactions to iron salts.
2014
Synthesis of phosphabenzenes by an iron-catalyzed [2+2+2] cycloaddition reaction of diynes with phosphaalkynes.
2015 Jun 22
Reactivity enhancement of iron sulfide nanoparticles stabilized by sodium alginate: Taking Cr (VI) removal as an example.
2017 Jul 5
Atomic Layer Deposition of Iron Sulfide and Its Application as a Catalyst in the Hydrogenation of Azobenzenes.
2017 Mar 13
Continuous sulfidogenic wastewater treatment with iron sulfide sludge oxidation and recycle.
2017 May 1
Patents

Sample Use Guides

Unknown
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:10:34 UTC 2023
Edited
by admin
on Sat Dec 16 08:10:34 UTC 2023
Record UNII
1OA214846O
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERROUS SULFATE SESQUIHYDRATE
Common Name English
FERROUS SULPHATE SESQUIHYDRATE
Common Name English
FERROHEMATOGEN
Brand Name English
TARDYFERON
Brand Name English
Code System Code Type Description
PUBCHEM
90478523
Created by admin on Sat Dec 16 08:10:34 UTC 2023 , Edited by admin on Sat Dec 16 08:10:34 UTC 2023
PRIMARY
CAS
13463-43-9
Created by admin on Sat Dec 16 08:10:34 UTC 2023 , Edited by admin on Sat Dec 16 08:10:34 UTC 2023
NON-SPECIFIC STOICHIOMETRY
EVMPD
SUB30109
Created by admin on Sat Dec 16 08:10:34 UTC 2023 , Edited by admin on Sat Dec 16 08:10:34 UTC 2023
PRIMARY
FDA UNII
1OA214846O
Created by admin on Sat Dec 16 08:10:34 UTC 2023 , Edited by admin on Sat Dec 16 08:10:34 UTC 2023
PRIMARY
DRUG BANK
DBSALT002668
Created by admin on Sat Dec 16 08:10:34 UTC 2023 , Edited by admin on Sat Dec 16 08:10:34 UTC 2023
PRIMARY
SMS_ID
100000092908
Created by admin on Sat Dec 16 08:10:34 UTC 2023 , Edited by admin on Sat Dec 16 08:10:34 UTC 2023
PRIMARY
Related Record Type Details
ANHYDROUS->SOLVATE
Related Record Type Details
ACTIVE MOIETY