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Details

Stereochemistry ACHIRAL
Molecular Formula Fe.O4S.H2O
Molecular Weight 169.923
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERROUS SULFATE MONOHYDRATE

SMILES

O.[Fe++].[O-]S([O-])(=O)=O

InChI

InChIKey=XBDUTCVQJHJTQZ-UHFFFAOYSA-L
InChI=1S/Fe.H2O4S.H2O/c;1-5(2,3)4;/h;(H2,1,2,3,4);1H2/q+2;;/p-2

HIDE SMILES / InChI
Molecular Formula Fe
Molecular Weight 55.845
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula HO4S
Molecular Weight 97.071
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including http://www.minapharm.com/Public/ProductDetails.aspx?ProductCode=FERRO_SANO&langParam=en

Iron(II) gluconate (also known as a ferrous gluconate) is used in the treatment of hypochromic anemia. The real problem of iron therapy is not the theoretical utilization of iron, or the reticulocyte response, or even the daily increase of hemoglobin. These are important only as they indicate the return of the patients' blood to normal in a reasonably short time without undue inconvenience. Most patients suffering from hypochromic anemia respond well to most forms of iron when administered in adequate dosage. For the patients who cannot tolerate the usual iron compounds, it is important to have a medication which is effective and which causes minimum disturbance. Ferrous gluconate is such a medicament.

Originator

Approval Year

1921
1467
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Palliative
Not Provided
504
Unknown

Approved Use

Unknown
Primary
Approved
8429
Ferro Sanol Duodenal

Approved Use

Ferro Sanol is an iron substitute in case of latent or manifest iron deficiency with and without development of anaemia.
PubMed

PubMed

TitleDatePubMed
FERROUS IODIDE AS A SUBSTITUTE FOR VITAMIN A IN RATS.
1932 Jul 1
FERROUS IODIDE AND LINOLEIC ACID IN VITAMIN A DEFICIENCY. A REPLY TO CERTAIN CRITICISMS.
1932 Nov 11
THE ADMINISTRATION OF FERROUS IODIDE AND LINOLEIC ACID TO RATS DEPRIVED OF VITAMIN A.
1932 Sep 30
THE USE OF FERROUS GLUCONATE IN THE TREATMENT OF HYPOCHROMIC ANEMIA.
1937 Jul
[Ferrous lactate as an oral iron preparation for therapeutic use].
1954 Nov 27
Clinical appraisal of drugs with special reference to a new chelate hematinic.
1957 Jul 11
[FERROUS ASPARTATE IN THERAPY].
1964 Jan 1
[Historical notes on the therapy of depression].
1986 Nov 22
Determination of water in ferrous lactate by near infrared reflectance spectroscopy with a fibre-optic probe.
1997 Oct
Decreased treatment failure rates following duodenal release ferrous glycine sulfate in iron deficiency anemia associated with autoimmune gastritis and Helicobacter pylori gastritis.
2007
Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice.
2009
Bioleaching of heavy metals from sewage sludge by indigenous iron-oxidizing microorganisms using ammonium ferrous sulfate and ferrous sulfate as energy sources: a comparative study.
2009 Nov 15
Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis.
2011 Jun 10
Tolerability of different oral iron supplements: a systematic review.
2013 Apr
Effect of abomasal ferrous lactate infusion on phosphorus absorption in lactating dairy cows.
2013 Jul
A practical and successful desensitization protocol for immediate hypersensitivity reactions to iron salts.
2014
Synthesis of phosphabenzenes by an iron-catalyzed [2+2+2] cycloaddition reaction of diynes with phosphaalkynes.
2015 Jun 22
Reactivity enhancement of iron sulfide nanoparticles stabilized by sodium alginate: Taking Cr (VI) removal as an example.
2017 Jul 5
Atomic Layer Deposition of Iron Sulfide and Its Application as a Catalyst in the Hydrogenation of Azobenzenes.
2017 Mar 13
Continuous sulfidogenic wastewater treatment with iron sulfide sludge oxidation and recycle.
2017 May 1
Patents

Patents

CN105565963
36
US20020127665
36
US2009028810
36
US20150202224
36
US2877253
36
US3091626
36
US5534268
36
US6407138
36
US8080520
36
US8802114
36

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:36:31 GMT 2023
Edited
by admin
on Fri Dec 15 15:36:31 GMT 2023
Record UNII
RIB00980VW
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FERROUS SULFATE MONOHYDRATE
Common Name English
SULFURIC ACID, IRON(2+) SALT (1:1), HYDRATE
Common Name English
FERROUS SULFATE, DRIED [EP IMPURITY]
Common Name English
FERROUS SULFATE, DRIED
EP   FCC   USP  
Common Name English
IRON(II) SULFATE MONOHYDRATE
Systematic Name English
IRON(2+) SULFATE (1:1) HYDRATE
Common Name English
FERROUS SULFATE EXSICCATED
WHO-DD  
Common Name English
DRIED FERROUS SULFATE
Common Name English
FERROUS SULFATE, DRIED [USP IMPURITY]
Common Name English
FERROUS SULFATE MONOHYDRATE [MI]
Common Name English
Ferrous sulfate exsiccated [WHO-DD]
Common Name English
FESPAN
Brand Name English
FERRO-GRADUMET
Brand Name English
FERROUS SULFATE, DRIED [EP MONOGRAPH]
Common Name English
IRON(2+) SULPHATE (1:1) HYDRATE
Common Name English
FERROUS SULPHATE, DRIED
Common Name English
FERORITARD
Brand Name English
FEROMAX
Brand Name English
DRIED FERROUS SULPHATE
Common Name English
EXSICCATED FERROUS SULFATE
Common Name English
FERROUS SULFATE, DRIED [FCC]
Common Name English
DRIED FERROUS SULFATE [USP MONOGRAPH]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 50507
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
Code System Code Type Description
SMS_ID
100000091646
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
PRIMARY
NCI_THESAURUS
C1505
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
CONCEPT Dietary Supplement
NCI_THESAURUS
C65678
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
PRIMARY
EPA CompTox
DTXSID9034608
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
PRIMARY
CAS
17375-41-6
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
PRIMARY
PUBCHEM
62712
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
PRIMARY
DRUG BANK
DBSALT002667
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
PRIMARY
MERCK INDEX
m5354
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
PRIMARY Merck Index
FDA UNII
RIB00980VW
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
PRIMARY
DAILYMED
RIB00980VW
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
PRIMARY
CHEBI
75834
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
PRIMARY
EVMPD
SUB13878MIG
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
PRIMARY
CAS
13463-43-9
Created by admin on Fri Dec 15 15:36:31 GMT 2023 , Edited by admin on Fri Dec 15 15:36:31 GMT 2023
NON-SPECIFIC STOICHIOMETRY
Related Record Type Details
Structure of FERROUS CATION
PARENT -> SALT/SOLVATE
Structure of FERROUS SULFATE ANHYDROUS
ANHYDROUS->SOLVATE
Related Record Type Details
Structure of FERROUS CATION
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