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Details

Stereochemistry ACHIRAL
Molecular Formula C6H6O7.Fe
Molecular Weight 245.953
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FERROUS CITRATE

SMILES

[Fe++].OC(=O)C(O)(CC([O-])=O)CC([O-])=O

InChI

InChIKey=APVZWAOKZPNDNR-UHFFFAOYSA-L
InChI=1S/C6H8O7.Fe/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+2/p-2

HIDE SMILES / InChI
Molecular Formula C6H6O7
Molecular Weight 190.1076
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Fe
Molecular Weight 55.845
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/3541174 | https://books.google.ru/books?id=7mxyBgAAQBAJ&pg=PA13&lpg=PA13&dq=%22ferrous+iodide%22+anemia&source=bl&ots=ZGyFhUiJZ4&sig=IZOhRVaGmlwX7GcqgoE6rnCsCa4&hl=ru&sa=X&ved=0ahUKEwjYu7PCyYHUAhWiQpoKHR6cCfcQ6AEIUjAJ#v=onepage&q=%22ferrous%20iodide%22&f=false

There is no information about biological and pharmacological application of Iron(II) fluoride (also known as ferrous fluoride). It is known, that this substance is used to catalyze some organic reactions.

Originator

Approval Year

1921
1468
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Not Provided
511
Unknown

Approved Use

Unknown
Palliative
Not Provided
511
Unknown

Approved Use

Unknown
Primary
Approved
8583
Ferro Sanol Duodenal

Approved Use

Ferro Sanol is an iron substitute in case of latent or manifest iron deficiency with and without development of anaemia.
Curative
Approved
8583
RADIOGARDASE

Approved Use

Insoluble Prussian blue is indicated for treatment of patients with known or suspected internal contamination with radioactive cesium and/or radioactive or non-radioactive thallium to increase their rates of elimination.

Launch Date

2003
PubMed

PubMed

TitleDatePubMed
Reactivity enhancement of iron sulfide nanoparticles stabilized by sodium alginate: Taking Cr (VI) removal as an example.
2017-07-05
Continuous sulfidogenic wastewater treatment with iron sulfide sludge oxidation and recycle.
2017-05-01
Atomic Layer Deposition of Iron Sulfide and Its Application as a Catalyst in the Hydrogenation of Azobenzenes.
2017-03-13
Synthesis of phosphabenzenes by an iron-catalyzed [2+2+2] cycloaddition reaction of diynes with phosphaalkynes.
2015-06-22
A practical and successful desensitization protocol for immediate hypersensitivity reactions to iron salts.
2014
Effect of abomasal ferrous lactate infusion on phosphorus absorption in lactating dairy cows.
2013-07
Tolerability of different oral iron supplements: a systematic review.
2013-04
Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis.
2011-06-10
The effect of iron treatment on adhesion molecules in patients with iron deficiency anemia.
2010-12
Bioleaching of heavy metals from sewage sludge by indigenous iron-oxidizing microorganisms using ammonium ferrous sulfate and ferrous sulfate as energy sources: a comparative study.
2009-11-15
Reversal of multidrug resistance by magnetic Fe3O4 nanoparticle copolymerizating daunorubicin and 5-bromotetrandrine in xenograft nude-mice.
2009
Decreased treatment failure rates following duodenal release ferrous glycine sulfate in iron deficiency anemia associated with autoimmune gastritis and Helicobacter pylori gastritis.
2007
Determination of water in ferrous lactate by near infrared reflectance spectroscopy with a fibre-optic probe.
1997-10
[Historical notes on the therapy of depression].
1986-11-22
[FERROUS ASPARTATE IN THERAPY].
1964-01-01
Clinical appraisal of drugs with special reference to a new chelate hematinic.
1957-07-11
[Ferrous lactate as an oral iron preparation for therapeutic use].
1954-11-27
THE USE OF FERROUS GLUCONATE IN THE TREATMENT OF HYPOCHROMIC ANEMIA.
1937-07
FERROUS IODIDE AND LINOLEIC ACID IN VITAMIN A DEFICIENCY. A REPLY TO CERTAIN CRITICISMS.
1932-11-11
THE ADMINISTRATION OF FERROUS IODIDE AND LINOLEIC ACID TO RATS DEPRIVED OF VITAMIN A.
1932-09-30
FERROUS IODIDE AS A SUBSTITUTE FOR VITAMIN A IN RATS.
1932-07-01
Patents

Patents

CN105565963
37
US20020127665
37
US2009028810
37
US20150202224
37
US2877253
37
US3091626
37
US5534268
37
US6407138
37
US8080520
37
US8802114
37

Sample Use Guides

In Vivo Use Guide
Adults should usually take one capsule a day. In cases of pronounced iron deficiency, adults can be given a dosage 2 to 3 times higher at the beginning of therapy. A daily dose of more than 5 mg Fe2+/kg body weight should in-well founded exceptional cases not be exceeded.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:49:45 GMT 2025
Edited
by admin
on Mon Mar 31 17:49:45 GMT 2025
Record UNII
33KM3X4QQW
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CITRIC ACID, IRON(2+) SALT
Preferred Name English
FERROUS CITRATE
FCC   HSDB   MI   WHO-DD  
Common Name English
IRON(II) CITRATE
Systematic Name English
FERROUS CITRATE [MI]
Common Name English
FERROUS CITRATE [HSDB]
Common Name English
Ferrous citrate [WHO-DD]
Common Name English
FERROUS CITRATE [FCC]
Common Name English
Classification Tree Code System Code
CFR 21 CFR 184.1307C
Created by admin on Mon Mar 31 17:49:45 GMT 2025 , Edited by admin on Mon Mar 31 17:49:45 GMT 2025
Code System Code Type Description
EVMPD
SUB13864MIG
Created by admin on Mon Mar 31 17:49:45 GMT 2025 , Edited by admin on Mon Mar 31 17:49:45 GMT 2025
PRIMARY
EPA CompTox
DTXSID701018441
Created by admin on Mon Mar 31 17:49:45 GMT 2025 , Edited by admin on Mon Mar 31 17:49:45 GMT 2025
PRIMARY
CAS
23383-11-1
Created by admin on Mon Mar 31 17:49:45 GMT 2025 , Edited by admin on Mon Mar 31 17:49:45 GMT 2025
PRIMARY
PUBCHEM
11064683
Created by admin on Mon Mar 31 17:49:45 GMT 2025 , Edited by admin on Mon Mar 31 17:49:45 GMT 2025
PRIMARY
HSDB
460
Created by admin on Mon Mar 31 17:49:45 GMT 2025 , Edited by admin on Mon Mar 31 17:49:45 GMT 2025
PRIMARY
MESH
C016600
Created by admin on Mon Mar 31 17:49:45 GMT 2025 , Edited by admin on Mon Mar 31 17:49:45 GMT 2025
PRIMARY
MERCK INDEX
m5341
Created by admin on Mon Mar 31 17:49:45 GMT 2025 , Edited by admin on Mon Mar 31 17:49:45 GMT 2025
PRIMARY Merck Index
ECHA (EC/EINECS)
245-625-1
Created by admin on Mon Mar 31 17:49:45 GMT 2025 , Edited by admin on Mon Mar 31 17:49:45 GMT 2025
PRIMARY
FDA UNII
33KM3X4QQW
Created by admin on Mon Mar 31 17:49:45 GMT 2025 , Edited by admin on Mon Mar 31 17:49:45 GMT 2025
PRIMARY
SMS_ID
100000078449
Created by admin on Mon Mar 31 17:49:45 GMT 2025 , Edited by admin on Mon Mar 31 17:49:45 GMT 2025
PRIMARY
WIKIPEDIA
IRON(II) CITRATE
Created by admin on Mon Mar 31 17:49:45 GMT 2025 , Edited by admin on Mon Mar 31 17:49:45 GMT 2025
PRIMARY
Related Record Type Details
Structure of Anhydrous citric acid
PARENT -> SALT/SOLVATE
Structure of FERROUS CATION
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of FERROUS CATION
ACTIVE MOIETY
NIH
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