U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula H2S
Molecular Weight 34.081
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HYDROGEN SULFIDE

SMILES

S

InChI

InChIKey=RWSOTUBLDIXVET-UHFFFAOYSA-N
InChI=1S/H2S/h1H2

HIDE SMILES / InChI
Molecular Formula H2S
Molecular Weight 34.081
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

A sulfide ion is composed of a lone sulfur atom. Its charge is negative two, giving sulfides this formula: S^2-. Sulfide is a strong base, so solutions of sulfide in water are basic, due to hydrolysis. One well-known ionic compound with a sulfide ion is H_2S. The infamous rotten-egg smell often associated with sulfur originates from this compound. Sodium sulfide nonahydrate is used in the formation of surface functionalized cadmium sulfide quantum dots.

Approval Year

2018
400
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Approved
8307
DR. SCHOLLS INGROWN TOENAIL PAIN RELIEVER

Approved Use

Use: - For temporary relief of pain and discomfort from ingrown toenails.

Launch Date

1.05217917E12
PubMed

PubMed

TitleDatePubMed
Investigations into black extrinsic tooth stain.
1977 Aug
Convulsions following application of gamma benzene hexachloride.
1981 Jul
Clinical comparison of two radiocolloids for internal mammary lymphoscintigraphy.
1985 Dec
Widespread occurrence of bacterial thiol methyltransferases and the biogenic emission of methylated sulfur gases.
1987 Jul
Activity of polymorphonuclear leukocytes in the presence of sulfide.
1989 Sep
Lung dysfunction in animal confinement workers--chairman's report to the Scientific Committee of the Third International Symposium: issues in health, safety and agriculture, held in Saskatoon, Saskatchewan, Canada, May 10-15, 1992.
1992
Chemosensory event-related potentials in the investigation of interactions between the olfactory and the somatosensory (trigeminal) systems.
1992 Sep
The usefulness of thiosulfate as an indicator of hydrogen sulfide poisoning: three cases.
1997
A fatal case of hydrogen sulfide poisoning in a geothermal power plant.
1998 Jul
Hydrogen sulfide and colonic epithelial metabolism: implications for ulcerative colitis.
2001 Aug
Gas production by feces of infants.
2001 May
HG/LT-GC/ICP-MS coupling for identification of metal(loid) species in human urine after fish consumption.
2001 Nov
Fatal and nonfatal poisoning by hydrogen sulfide at an industrial waste site.
2002 May
Novel neural modulators.
2003
Production of the neuromodulator H2S by cystathionine beta-synthase via the condensation of cysteine and homocysteine.
2004 Dec 10
Biochemical differentiation and comparison of Desulfovibrio species and other phenotypically similar genera.
2005 Aug
The third gas: H2S regulates perfusion pressure in both the isolated and perfused normal rat liver and in cirrhosis.
2005 Sep
Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder.
2008 Feb
Contractile and vasorelaxant effects of hydrogen sulfide and its biosynthesis in the human internal mammary artery.
2008 Feb
Disulfides as cyanide antidotes: evidence for a new in vivo oxidative pathway for cyanide detoxification.
2009 Dec
S-Propargyl-cysteine (SPRC) attenuated lipopolysaccharide-induced inflammatory response in H9c2 cells involved in a hydrogen sulfide-dependent mechanism.
2011 Jun
Indoor air pollutants and health in the United Arab Emirates.
2012 May
Sulfide induces apoptosis and Rho kinase-dependent cell blebbing in Jurkat cells.
2013 Jul
Downregulation of cystathionine β-synthase/hydrogen sulfide contributes to rotenone-induced microglia polarization toward M1 type.
2014 Aug 22
H2S inhibition of chemical hypoxia-induced proliferation of HPASMCs is mediated by the upregulation of COX-2/PGI2.
2014 Feb
Patents

Patents

03968062
5
04011225
6
04013678
7
04013769
12
04020170
5
04045520
5
04057647
16
04059433
6
Substance Class Chemical
Created
by admin
on Fri Dec 16 22:31:20 UTC 2022
Edited
by admin
on Fri Dec 16 22:31:20 UTC 2022
Record UNII
YY9FVM7NSN
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HYDROGEN SULFIDE
FHFI   HSDB   MART.   MI  
Systematic Name English
SULPHUR HYDROGENISATUM
HPUS  
Common Name English
HYDROGEN SULFIDE [MI]
Common Name English
HYDROGEN SULFIDE [HSDB]
Common Name English
DIHYDROGEN MONOSULFIDE
Common Name English
UN 1053
Code English
SULPHUR HYDROGENISATUM [HPUS]
Common Name English
FEMA NO. 3779
Code English
HYDROGEN SULFIDE [FHFI]
Common Name English
DIHYDROGEN MONOSULPHIDE
Common Name English
HYDROGEN SULPHIDE
Systematic Name English
HYDROGEN SULFIDE [MART.]
Common Name English
Classification Tree Code System Code
LOINC 2438-0
Created by admin on Fri Dec 16 22:31:21 UTC 2022 , Edited by admin on Fri Dec 16 22:31:21 UTC 2022
Code System Code Type Description
EVMPD
SUB33127
Created by admin on Fri Dec 16 22:31:21 UTC 2022 , Edited by admin on Fri Dec 16 22:31:21 UTC 2022
PRIMARY
HSDB
576
Created by admin on Fri Dec 16 22:31:21 UTC 2022 , Edited by admin on Fri Dec 16 22:31:21 UTC 2022
PRIMARY
CHEBI
29919
Created by admin on Fri Dec 16 22:31:21 UTC 2022 , Edited by admin on Fri Dec 16 22:31:21 UTC 2022
PRIMARY
WIKIPEDIA
HYDROGEN SULFIDE
Created by admin on Fri Dec 16 22:31:21 UTC 2022 , Edited by admin on Fri Dec 16 22:31:21 UTC 2022
PRIMARY
MESH
D006862
Created by admin on Fri Dec 16 22:31:21 UTC 2022 , Edited by admin on Fri Dec 16 22:31:21 UTC 2022
PRIMARY
EPA CompTox
DTXSID4024149
Created by admin on Fri Dec 16 22:31:21 UTC 2022 , Edited by admin on Fri Dec 16 22:31:21 UTC 2022
PRIMARY
CAS
7783-06-4
Created by admin on Fri Dec 16 22:31:21 UTC 2022 , Edited by admin on Fri Dec 16 22:31:21 UTC 2022
PRIMARY
PUBCHEM
402
Created by admin on Fri Dec 16 22:31:21 UTC 2022 , Edited by admin on Fri Dec 16 22:31:21 UTC 2022
PRIMARY
MERCK INDEX
M6107
Created by admin on Fri Dec 16 22:31:21 UTC 2022 , Edited by admin on Fri Dec 16 22:31:21 UTC 2022
PRIMARY Merck Index
CHEBI
16136
Created by admin on Fri Dec 16 22:31:21 UTC 2022 , Edited by admin on Fri Dec 16 22:31:21 UTC 2022
PRIMARY
FDA UNII
YY9FVM7NSN
Created by admin on Fri Dec 16 22:31:21 UTC 2022 , Edited by admin on Fri Dec 16 22:31:21 UTC 2022
PRIMARY
ECHA (EC/EINECS)
231-977-3
Created by admin on Fri Dec 16 22:31:21 UTC 2022 , Edited by admin on Fri Dec 16 22:31:21 UTC 2022
PRIMARY
Related Record Type Details
Structure of AMMONIUM SULFIDE
SALT/SOLVATE -> PARENT
Structure of ZINC SULFIDE
SALT/SOLVATE -> PARENT
Structure of LITHIUM SULFIDE
SALT/SOLVATE -> PARENT
Structure of TECHNETIUM SULFIDE TC-99M
SALT/SOLVATE -> PARENT
Structure of MERCURIC SULFIDE
SALT/SOLVATE -> PARENT
Structure of POTASSIUM SULFIDE PENTAHYDRATE
SALT/SOLVATE -> PARENT
Structure of SODIUM SULFIDE NONAHYDRATE
SALT/SOLVATE -> PARENT
Structure of CADMIUM SULFIDE
SALT/SOLVATE -> PARENT
Structure of BISMUTH SULFIDE
SALT/SOLVATE -> PARENT
Structure of STRONTIUM SULFIDE
SALT/SOLVATE -> PARENT
Structure of INDIUM SULFIDE
SALT/SOLVATE -> PARENT
Structure of COBALTOUS SULFIDE
SALT/SOLVATE -> PARENT
Structure of LEAD SULFIDE
SALT/SOLVATE -> PARENT
Structure of POTASSIUM BISULFIDE
SALT/SOLVATE -> PARENT
Structure of AMMONIUM BISULFIDE
SALT/SOLVATE -> PARENT
Structure of STANNOUS SULFIDE
SALT/SOLVATE -> PARENT
Structure of ANTIMONY TRISULFIDE
SALT/SOLVATE -> PARENT
Structure of SILVER SULFIDE
SALT/SOLVATE -> PARENT
Structure of SODIUM BISULFIDE
SALT/SOLVATE -> PARENT
Structure of CALCIUM SULFIDE
SALT/SOLVATE -> PARENT
Structure of FERROUS SULFIDE
SALT/SOLVATE -> PARENT
Structure of GOLD MONOSULFIDE
SALT/SOLVATE -> PARENT
Structure of SODIUM SULFIDE ANHYDROUS
SALT/SOLVATE -> PARENT
Structure of SODIUM SULFIDE PENTAHYDRATE
SALT/SOLVATE -> PARENT
Structure of BARIUM SULFIDE
SALT/SOLVATE -> PARENT
Structure of ANTIMONY PENTASULFIDE
SALT/SOLVATE -> PARENT
Structure of POTASSIUM SULFIDE
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of HYDROGEN SULFIDE
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966